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GROWTH INHIBITION OF CLINICALLY RESISTANT BACTERIA BY MARINE BACTERIA ASSOCIATED WITH SPONGE Aaptos sp.


 
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1. Title Title of document GROWTH INHIBITION OF CLINICALLY RESISTANT BACTERIA BY MARINE BACTERIA ASSOCIATED WITH SPONGE Aaptos sp.
 
2. Creator Author's name, affiliation, country Duhita S Kencana; Indonesia
 
2. Creator Author's name, affiliation, country Rory A Hutagalung; Indonesia
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) growth inhibition, marine bacteria, sponge Aaptos sp., resistant bacteria
 
4. Description Abstract The improper and uncontrolled uses of antibiotics against pathogenic bacteria have resulted in
the occurrence of Multi Drugs Resistant (MDR) strains. There is now an urgency to find alternative
antibiotics to combat the MDR strains. Sponge associated microorganisms are among of the most
interesting and promising marine natural product sources, which produce polyketide and non
ribosomal peptide products with various biological activities. In this study, marine bacteria were
isolated from sponge Aaptos sp. collected from North Java Sea, and were screened for antibacterial
activity against MDR strains. Three out of 64 bacterial isolates were successfully screened and were
found to be active against MDR strains, in which 2 isolates (SPA1 and SPA5) were active against
resistant strain Escherichia coli and 1 isolate (SPA21) against resistant strain Proteus sp., respectively.
These active isolates were also capable of amplifying NRPS gene fragments necessary for the
biosynthesis of non ribosomal peptides. The identification results revealed that the active isolates are
Halomonas aquamarina, Alpha proteobacterium, and Pseudoalteromonas luteviolacea

 
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6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 19-05-2011
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://ejournal.undip.ac.id/index.php/coastdev/article/view/907
 
11. Source Title; vol., no. (year) JOURNAL OF COASTAL DEVELOPMENT; Vol 11, No 2 (2008): Volume 11, Number 2, Year 2008
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c)