GROWTH INHIBITION OF CLINICALLY RESISTANT BACTERIA BY MARINE BACTERIA ASSOCIATED WITH SPONGE Aaptos sp.
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1. | Title | Title of document | GROWTH INHIBITION OF CLINICALLY RESISTANT BACTERIA BY MARINE BACTERIA ASSOCIATED WITH SPONGE Aaptos sp. |
2. | Creator | Author's name, affiliation, country | Duhita S Kencana; Indonesia |
2. | Creator | Author's name, affiliation, country | Rory A Hutagalung; Indonesia |
3. | Subject | Discipline(s) | |
3. | Subject | Keyword(s) | growth inhibition, marine bacteria, sponge Aaptos sp., resistant bacteria |
4. | Description | Abstract | The improper and uncontrolled uses of antibiotics against pathogenic bacteria have resulted in the occurrence of Multi Drugs Resistant (MDR) strains. There is now an urgency to find alternative antibiotics to combat the MDR strains. Sponge associated microorganisms are among of the most interesting and promising marine natural product sources, which produce polyketide and non ribosomal peptide products with various biological activities. In this study, marine bacteria were isolated from sponge Aaptos sp. collected from North Java Sea, and were screened for antibacterial activity against MDR strains. Three out of 64 bacterial isolates were successfully screened and were found to be active against MDR strains, in which 2 isolates (SPA1 and SPA5) were active against resistant strain Escherichia coli and 1 isolate (SPA21) against resistant strain Proteus sp., respectively. These active isolates were also capable of amplifying NRPS gene fragments necessary for the biosynthesis of non ribosomal peptides. The identification results revealed that the active isolates are Halomonas aquamarina, Alpha proteobacterium, and Pseudoalteromonas luteviolacea |
5. | Publisher | Organizing agency, location | |
6. | Contributor | Sponsor(s) | |
7. | Date | (YYYY-MM-DD) | 19-05-2011 |
8. | Type | Status & genre | Peer-reviewed Article |
8. | Type | Type | |
9. | Format | File format | |
10. | Identifier | Uniform Resource Identifier | https://ejournal.undip.ac.id/index.php/coastdev/article/view/907 |
11. | Source | Title; vol., no. (year) | JOURNAL OF COASTAL DEVELOPMENT; Vol 11, No 2 (2008): Volume 11, Number 2, Year 2008 |
12. | Language | English=en | en |
13. | Relation | Supp. Files | |
14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
15. | Rights | Copyright and permissions |
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