DOI: https://doi.org/10.14710/gt.v21i1.32287

EKSTRAKSI SENYAWA BIOAKTIF THEAFLAVIN TEH OOLONG (CAMELLIA SINESIS) DENGAN AIR SEBAGAI GREEN SOLVENT

*Rizka Amalia orcid scopus  -  Program Studi Sarjana Terapan Teknologi Rekayasa Kimia Industri, Sekolah Vokasi, Universitas Diponegoro, Indonesia
Mohamad Endy Yulianto scopus  -  Program Studi Sarjana Terapan Teknologi Rekayasa Kimia Industri, Sekolah Vokasi, Universitas Diponegoro, Indonesia
Susiana Purwantisari  -  Program Studi Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro, Indonesia
Yusuf Arya Yudanto  -  Program Studi Sarjana Terapan Teknologi Rekayasa Kimia Industri, Sekolah Vokasi, Universitas Diponegoro, Indonesia
Ilyas Teguh Pangestu  -  Program Studi D-III Teknologi Kimia, Sekolah Vokasi, Universitas Diponegoro, Indonesia

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Abstract

Theaflavin, a polyphenolic compounds found  in oolong tea and black tea, thought to have medicinal potency. Theaflavins and their derivatives such as theaflavin gallate have shown a broad spectrum of antiviral activity against several viruses, including influenza A, B and hepatitis C viruses. Previous research show that theaflavins could inhibit RdRp activity through blocking the active site in the catalytic pocket of RdRp in SARS‐CoV‐2, SARS‐CoV and MERS‐CoV.. This research aims to extract theaflavins in oolong tea with water solvent at a temperature of 100oC, pressure > 1 atm and varied extraction times (10-60 minutes). The effect of oolong tea extraction time towards the  theaflavin content was observed. The results showed that with the longer extraction time, the theaflavin levels were reduced due to the degradation of thermal theaflavins into thearubigins. The model exponential equation obtained is  y=14,91488 e-0,2631x + 0,11865, with the R2=0.99161. The best operating conditions was obtained at 10 minutes of extraction time, resulted in 1.19% of the total theaflavin content of oolong tea.

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Keywords: teh oolong; theaflavin; ekstraksi; green solvent; SARS-CoV-2
Funding: universitas diponegoro

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  1. Optimization of process parameter for theaflavin extraction from black tea (Camellia sinensis) as an inhibitor potential of rdrp SARS-CoV-2 using response surface methodology

    Rizka Amalia, Mohamad Endy Yulianto, Susiana Purwantisari, Nabil Uzzul Islam, Yusuf Arya Yudanto. THE 6TH INTERNATIONAL CONFERENCE ON ENERGY, ENVIRONMENT, EPIDEMIOLOGY AND INFORMATION SYSTEM (ICENIS) 2021: Topic of Energy, Environment, Epidemiology, and Information System, 2683 , 2023. doi: 10.1063/5.0125296

Last update: 2024-11-20 03:17:52

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