skip to main content


*E. Andreas  -  Faculty of Animal Science, Bogor Agricultural University,, Indonesia
C. Sumantri  -  Faculty of Animal Science, Bogor Agricultural University,, Indonesia
H. Nuraini  -  Faculty of Animal Science, Bogor Agricultural University,, Indonesia
A. Farajallah  -  Faculty of Mathemathics and Natural Science,, Indonesia
A. Anggraeni  -  Indonesian Research Institute for Animal Production ,, Indonesia

Citation Format:
Growth hormone (GH) is an anabolic hormone which sintesized and secreted by somatrotop cell inpituitary anterior lobe. GH exert its effect on growth and metabolism by interacting with a specificreceptor on the surface of the target cells. Growth hormone receptor (GHR) has been suggested ascandidate gene for traits related to meat production in Bovidae. The objectives of this study were toidentify polymorphism of GH and GHR genes in buffalo. The 452 DNA samples buffalo were collectedfrom five populations in Indonesia (Siborong-Borong-Medan (65), Lebak-Banten (29), Pandeglang-Banten (180), Semarang-Central Java, and Mataram-West Nusa Tenggara (103)). A gene fragment of theGH|AluI gene at 432 bp located on exon 3 and GHR|AluI gene at 298 bp on exon 10 were successfullyamplified by using the techniques of a PCR (polymerase chain reaction) and genotyped by PCR-RFLP(restriction fragment length polymorphism) then -SSCP (single strand conformation polymorphism). Theresults showed no polymorphisms were detected in these genes. All buffaloes tested had LL genotype forlocus GH|AluI and AA genotype for locus GHR|AluI.
Fulltext View|Download
Keywords: Buffalo. Growth Hormone. Growth Hormone Receptor. Polymorphism

Article Metrics:

Last update:

  1. Bovine Science - A Key to Sustainable Development

    Henny Nuraini, Edit Lesa Aditia, Bram Brahmantiyo. 2019. doi: 10.5772/intechopen.79904
  2. Polymorphism of GH Exon 2 (c.100A>G) and GH Exon 4 (c.68A>C) in Sapera Goat

    F Saputra, G S Dewi, A Anggraeni, C Sumantri. IOP Conference Series: Earth and Environmental Science, 788 (1), 2021. doi: 10.1088/1755-1315/788/1/012002
  3. Polymorphism detection of <i>DGAT1</i> and <i>Lep</i> genes in Anatolian water buffalo (<i>Bubalus bubalis</i>) populations in Turkey

    Raziye Işık, Emel Özkan Ünal, M. İhsan Soysal. Archives Animal Breeding, 65 (1), 2022. doi: 10.5194/aab-65-1-2022
  4. Identification of novel single nucleotide polymorphisms in the growth hormone ( GH ) gene in Anatolian water buffalo ( Bubalus bubalis ) populations in Turkey

    Emel Özkan Ünal, Raziye Işık, Mehmet İhsan Soysal. Revista Brasileira de Zootecnia, 49 , 2020. doi: 10.37496/rbz4920190260

Last update: 2024-04-19 13:45:49

No citation recorded.