Brebes district is one of areas that got impact of development “Trans Jawa” highway route. Network route is often become a trigger of changing the land use arrangement. However, base on common knowledge, the highway network route will bring up new region and kill the old region. The development of the new region has started in the knot area of the exit highway, the region is dominated with restaurants and Brebes Distric’s souvenir shops. The main purpose of this research is understanding the influence of exit highway on the land use in Brebes District. The research’s data has been analized by one of qualitative method, analysis descriptive qualitative technique. The conclusion of the reseach is the three knot areas of exit highway have their own characteristic. The Pejagan and East Brebes have their impact on land use around the knot corridor. However, the West Brebes’s impact is the changing of utilization around the corridor and it didn’t impact the land use around it. The changing has its own impact to the space structure in Brebes District as there is new region’s development in the knot of exit highway. On the opposite, this new development has its own negative impact on the old corridor that has developed before, especially to the north route. The business around north corridor experienced the degression of the sales as the outcome of the road user’s new route (Trans Jawa highway route), just like Bulakamba and Diponegoro Corridors.
exit toll; land use; road users