Efek Rebusan Daun Tapak Dara pada Dosis dan Frekuensi yang Berbeda terhadap Kerusakan dan Akumulasi Glikogen pada Hepar Mencit (Mus musculus)

Abstract

The aim of this research was to investigate the effect of boiled -Vinca rosea leaf for hepar and glycogen
accumulation in Mus musculus hepatocyts on several dosages, frequencies and the interaction of dosagesfrequencies.
The research used factorial experiment with Complete Randomize Design and continued with Duncan test at
5% level. The result of this experiment indicated that there was significant by different of dosage treatment. The
higher dosage boiled- Vinca rosea leaf that given into Mus musculus, the more hepatocyts damage. Hepatocyt injury
was indicated by swollen until atrophy cell with glycogen accumulation in the cytoplasm of hepatocyt.