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Simulasi Blood Type Inheritance dengan Pemrograman Software Wolfram

*Asep Komara Walkis Hayadri  -  Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro, Indonesia
Hermin Pancasakti Kusumaningrum  -  Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro, Indonesia
Anto Budiharjo  -  Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro, Indonesia

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Abstract

 Bioinformatics as an interdisciplinary science, combine biology, computer science, information technology, mathematics, and statistics in order to analyze and interprete biological data. Bioinformatics has been used for in silico analysis of biological questions using mathematical and statistical techniques. In silico analysis allows indirect simulation through a series of instructions put into a device, usually a computer. Nowadays, the simulation of biological aspects, especially genetics, with in silico method has been widely applied for several fields. The ABO blood type inheritance system in humans has rules that its mechanism can be applied into the Wolfram software programming, for example showing the possibility of blood groups being inherited from blood type O pairs with AB. The latest statistical data regarding the number of Indonesians who have reported their blood type has not yet reached 25% of the total population of Indonesia. Wolfram software is expected to be an accurate and fast blood type detector to record the entire population of Indonesia. The purpose of this study was to simulate Blood Type Inheritance with Wolfram Software Programming on ABO blood type inheritance data and see the suitability of the simulation results with real blood type inheritance data. The method used to simulate blood type inheritance is a survey of 12 families for the data of blood group, the next step is to enter the data one by one into the simulation model to observe the output results then matched with real data to determine the results of ABO blood type inheritance. Simulation of blood type inheritance can be done by programming the Wolfram Mathematica software and blood type data from 12 families can be simulated through the ABO blood inheritance system on Wolfram Mathematica, with details of the simulation predicting the blood groups of 2 families, simulation of 9 families according to real data, and simulation of 1 family does not match the real data.

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Keywords: Bioinformatics, Simulation, Blood Type Inheritance, Wolfram Mathematica.

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Last update: 2024-03-19 14:16:07

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