Pengaruh suplementasi glisin terhadap kadar serum transferrin receptor (stfr) dan kadar hemoglobin (hb)
Article Metrics: (Click on the Metric tab below to see the detail)
Background: Iron deficiency anemia ( IDA) is still become a health problem in female adolescents. Iron supplementation only as a treatment for IDA still can not reach an optimum results. With that result, there was necessary to developing a strategy for iron supplementation, once treatment with glicyne .
Objective: to describe the effect of glycine supplementation on serum transferrin receptor (sTfR) levels and Hemoglobin (Hb) levels in female teenagers with IDA.
Methods: This study was quasi experimental, pre post test control group design. The population was female teenagers age 12 – 18 years, Hb < 12 mg/dl, sTfR > 18,4 nmol/L, involving 50 subjects, devided into two groups. The first group was experiment group that given the supplement of 60 mg iron and 1 gr glycine a day for 4 weeks. The second group was control group that given the supplement of only 60 mg iron a day for 4 weeks. The data were analyzed with bivariate test, paired t test, independent t test.
Results: There was significantly lower decreased of sTfR levels in treatment group 6,923±10,13 nmol/L than control group 0.809,65±9,076 nmol/L with p=0,008, and significant increased of Hb levels in both treatment group 0,79±1,15 mg/dl and control group 0,22±0,48 mg/dl with p=0,03.
Conclusion: Glycine supplementation for 4 weeks decreased sTfR levels in female teenagers with IDA before controlled by vitamin c intake (p=0,04) and after controlled by vitamin c intake variable (p=0,002) and increased Hb levels before controlled by vitamin c intake (p=0,02) and after controlled by vitamin c intake variable (p=0,04).
The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Indonesian Journal of Nutrition and Department of Nutrition, Faculty of Medicine, Diponegoro University as publisher of the journal.
Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc., will be allowed only with a written permission from Indonesian Journal of Nutrition and Department of Nutrition, Faculty of Medicine, Diponegoro University.
Indonesian Journal of Nutrition and Department of Nutrition, Faculty of Medicine, Diponegoro University, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Indonesian Journal of Nutrition are sole and exclusive responsibility of their respective authors and advertisers.