DOI: https://doi.org/10.14710/jgi.7.1.37-42

Hubungan antara jenis asupan karbohidrat dan lemak dengan kadar small dense low density lipoprotein pada pasien penyakit jantung koroner

1Departemen Kardiologi dan Kedokteran Vaskular, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

2Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

Received: 3 Oct 2018; Published: 30 Dec 2018.

Citation Format:
Abstract

Background: small dense Low Density Lipoprotein (sdLDL) was the most atherogenic lipoprotein. Its influenced by internal and external factors including food consumption. Indonesian people mostly take a diet of high carbohydrate (CH) and fried food that believed to correlate with higher sdLDL level and predisposed to Coronary Heart Disease (CHD). There were 2 types of CH based on the processing ways, refined and non-refined CH.
Objectives: The study’s purpose was to prove the correlation between different types of CH and fat intake with the sdlDL level in CHD patients.
Methods: cross sectional in CHD patients hospitalized at Dr Kariadi hospital. The sdLDL and others lipid profile examined. The type and amount of CH and fat intakes per-day were collect from an interview using semi-quantitative food frequency questionnaire (SQFFQ) and food models. Pearson and Spearman test used for bivariate analysis. Confounding factors age, gender, physical activity, diabetes mellitus and smoking were analyzed. Variables with p<0,25 was included in multivariate analysis using linear regression test.
Results: There were 30 samples with CHD came with acute coronary syndrome (ACS). Mean of total CH intake per day was 267.75 gram. Mean of percentage of CH from total calories per day was 55.93%. This number was higher than advised which is 30-130 gram or <45% of total calorie per day. Mean of refined and non-refined CH intake was 161.80 and 57.81 gr/day. The total CH mostly from refined CH (76%) rather than non-refined. Mean of fat intake was 68 gr/day (32.76% of total energy per day), and the mean of sdLDL level was 26,54 mg/dl. Correlation between refined CH vs non-refined CH with the sdLDL levels (r=0.328; p=0.077 vs r=-0.184;p=0.331). Correlation between fat intake and sdLDL levels (r=0.44;p=0.15). Multivariate analysis was analyzing refined CH fat intake and age with sdLDL level (r=0,28;p=0,13 vs r=0.45;p=0.01 vs r=-0.15;p=0.44). There is significant correlation between fat intake and sdLDL levels with r=0.45
Conclusion: There was a significant correlation between fat intake and sdLDL levels in CHD patients. There is no significant correlation between refined and non-refined carbohydrates with sdLDL levels in CHD patients.

Fulltext View|Download
Keywords: refined carbohydrate; fat intake; sdLDL; coronary heart disease

Article Metrics:

Article Info
Section: Articles
Language : EN
Recent articles
Lingkar lengan atas dan panjang ulna sebagai parameter antropometri untuk memperkirakan berat badan dan tinggi badan orang dewasa Kadar seng dan kadar malondialdehyde pada penderita multi drug resistant tuberculosis dan tuberkulosis sensitif Hubungan antara jenis asupan karbohidrat dan lemak dengan kadar small dense low density lipoprotein pada pasien penyakit jantung koroner More recent articles
Most cited articles
Front Matter Karakteristik makanan pendamping ASI balita yang disubstitusi dengan tepung ikan lele dan labu kuning Determinan kejadian stunting pada bayi usia 6 bulan di Kota Semarang Front Matter Front-Matter More cited articles
  1. Supriyantoro, Primadi O, Vensya S, Budijanto D, Hardhana B, F S, dkk. Profil kesehatan indonesia tahun 2013. Jakarta: Kementrian Kesehatan RI; 2014
  2. Global health observatory map gallery. 2011
  3. Sharma SB, Garg S. Small dense ldl: Risk factor for coronary artery disease (cad) and its therapeutic modulation. Indian J Biochem Biophys. 2012;49:77-85
  4. Stone NJ, Robinson J, Lichtenstein AH, Merz CN, Blum CB, Eckel RH, et al. Acc/aha guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the american college of cardiology/american heart association task force on practice guidelines. Circulation. 2013;129:S1-45
  5. Lamarche B, Tchernof A, Moorjani S, Cantin B, Dagenais GR, Lupien PJ, et al. Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the que´bec cardiovascular study. Circulation. 1997;95:69-75
  6. Yazdandoust S, Parizadeh SM, Moohebati M, Yaghmaei P, Rahsepar AA, Tavallaie S, et al. Serum small dense low-density lipoprotein concentrations are elevated in patients with significant coronary artery stenosis and are related to features of the metabolic syndrome. Lipids. 2012;47:963-972
  7. Yulissa F. Pengaruh pemberian daging buah durian (Durio zibethinus L.) terhadap kadar profil lipid darah sukarelawan sehat [skripsi]. Medan (Indonesia): Universitas Sumatra Utara; 2013: 8-20
  8. Kementrian Kesehatan Republik Indonesia. Studi diet total : potret pola makan penduduk indonesia saat ini [internet]. 2015 [cited 2016 Jan 3]. Available from: www.depkes.go.id
  9. McManus DD, Gore J, Goldberg RJ. Recent trends in the incidence, treatment, and outcomes of patients with ST and Non-ST segment acute myocardial infarction. Am J Med. 2011 Jan; 124(1): 40-7
  10. Almatsier S. Prinsip dasar ilmu gizi.Jakarta: PT. Gramedia Pustaka Utama;2001:28-47
  11. Adar SE, Sinai T, Yosefy C, Henkin Y. Nutritional recommendationsfor cardiovascular disease prevention. Nutrients. 2013; 5:3646-83
  12. Sacks FM, Lichtenstein AH, WU JHY, Appel LJ, Creager MA, Etherton PM, et al. Dietary fats and cardiovascular disease: a presidential advisory from the american heart association. Circulation. 2017; 135:00
  13. Mozzafarian D. Dietary and policy priorities for cardiovascular disease, diabetes, and obesity: a comprehensive review. Circulation. 2016; 133: 187-225
  14. Hu FB. Are refined carbohydrates worse than saturated fat?. Am J Clin Nutr. 2010; 91: 1541-2
  15. Sugiri. High refined carbohydrate intake play role as important coronary artery disease risk factor.How can it be?. Unpublished.Asmiha.2013
  16. Parks EJ, Hellerstein MK. Carbohydrate-induced hypertriacylglycerolemia:hystorical perspective and review of biological mechanisms. Am J Clin Nutr. 2000;71:412-33
  17. Kasim-Karakas S, Lane E, Almario R, Mueller W, Walzem R. Effects of dietary fat restriction on particle size of plasma lipoproteins in postmenopausal women. PubMed [internet]. 1997 [cited 2016 Jan 7]; 46(4): 431–6. Available from: Pubmed

Last update:

  1. The study of rice bran cookies for diabetic diet and dyslipidemic diet

    Rizqie Auliana, Fitri Rahmawati, Wara Kushartanti, Cerika Rismayanthi, Kukuh Wahyudin Pratama, Manil Kara Kauki, Reza Adityas Trisnadi, Ardi Riyana, Danarstuti Utami, Desi Yunita Utami, Amran Amran, Ari Tri Astuti, Deni Hardianto, Muhammad Nazim Razali, Aida Mustapha, Syed Kamaruzaman Syed Ali. Fizjoterapia Polska, 24 (1), 2024. doi: 10.56984/8ZG2EF8m5D

Last update: 2024-04-25 05:39:06

No citation recorded.