DOI: https://doi.org/10.14710/jgi.13.1.25-34

Malnutrition inflammation in chronic kidney disease undergoing hemodialysis in Cipto Mangunkusumo Hospital

1Nutrition Installation, RSUPN Dr. Cipto Mangunkusumo, Jakarta Pusat, DKI Jakarta, Indonesia

2Department of Nutrition Science, Faculty of Public Health, Universitas Indonesia, Depok, Jawa Barat, Indonesia

Received: 3 Jan 2024; Revised: 19 Sep 2024; Accepted: 25 Sep 2024; Available online: 30 Dec 2024; Published: 30 Dec 2024.

Citation Format:
Abstract

Background: Malnutrition was a nutritional problem in hemodialysis with prevalence 50-70% and 2018 study at Cipto Mangunkusumo Hospital showed the prevalence was 39%.

Objectives: This study was team study of Renal and Hypertension Unit RSCM, using cross sectional design, primary data collected in February and May 2018.

Materials and Methods: The sample size used a hypothesis test with total sample of 120 patients. Data obtained through interviews and laboratory data obtained through medical records. Univariate, bivariate and multivariate analysis were carried out to see the determinant factors that influence the Malnutrition Inflammation Score (MIS).

Results: The results showed that there were relationship between sex (p<0.022), age (p<0.031), etiology chronic kidney disease (p<0.037), duration hemodialysis (p<0.025), protein intake (p<0.030) and grip strength (p<0.010). The determinant factors significantly associated with MIS were sex p<0.0001, age p<0.014, protein intake p<0.018, and grip strength p<0.017.

Conclusion: The conclusions of this study were the prevalence of inflammatory malnutrition in hemodialysis patients was 55.8%, male had risk of 4.1 malnutrition, age ≥40 years had risk of 3.1, inadequate protein intake had risk 2.8 times malnutrition and less grip strength as a protective variable had a 0.23 times lower risk.

Keywords : Chronic kidney disease; hemodialysis; malnutrition inflammation; nutritional status


Fulltext View|Download
Keywords: Chronic kidney disease; hemodialysis; malnutrition inflammation; nutritional status

Article Metrics:

Article Info
Section: Articles
Language : EN
Recent articles
Differences in non-high density lipoprotein levels, blood pressure and waist circumference between normal-weight obesity, lean, and obese women Effect of vitamin D3 supplementation on serum 25 (OH)D Levels, hand grip strength, blood sugar levels, and cognitive function in the elderly Nutrition transition and the risk of over-nutrition among female adolescents in Indonesia: analysis of Indonesian family life survey data 2007 and 2014 More recent articles
Most cited articles
Keragaman pangan, pola asuh makan dan kejadian stunting pada balita usia 24-59 bulan Front-Matter Pengaruh pemberian jus mangga terhadap profil lipid dan malondialdehyde pada tikus yang diberi minyak jelantah Determinan kejadian stunting pada bayi usia 6 bulan di Kota Semarang Sitotoksisitas in vitro ekstrak etanolik buah parijoto (Medinilla speciosa, reinw.ex bl.) terhadap sel kanker payudara T47D More cited articles
  1. PERNEFRI. PERNEFRI - KONSENSUS NUTRISI CKD.pdf. Jakarta: PT.Kalbe Farma Tbk; 2011. 58 p
  2. Yusra K, Malhi T, Sarriff A, Khan A. Prevalence of Chronic Kidney Disease in Asia: A Systematic Review of Population-Based Studies. Int J Nephrol Renovasc Dis. 2018;11:165–72
  3. Sahathevan S, Khor BH, Ng HM, Gafor AHA, Daud ZAM, Mafra D, et al. Understanding development of malnutrition in hemodialysis patients: A narrative review. Nutrients. 2020;12:1–30
  4. Carrero JJ, Thomas F, Nagy K, Arogundade F, Avesani CM, Chan M, et al. Global Prevalence of Protein-Energy Wasting in Kidney Disease: A Meta-analysis of Contemporary Observational Studies From the International Society of Renal Nutrition and Metabolism. J Ren Nutr. 2018;28:380–92
  5. Behrooz E, Ata-Mohammad D, Abdol-Hamed Yapan-Gharavi. Malnutrition-Inflammation Score in Hemodialysis Patients. Zahedan J Res Med Sci. 2014;16:25–8
  6. Hamuktiono RP, Supriyadi R, Suraya N. Malnutrition – Inflammation Score ( MIS ) and Physical Activity among Hemodialysis Patients. Althea Med J. 2015;4:601–7
  7. As’habi A, Tabibi H, Nozary-Heshmati B, Mahdavi-Mazdeh M, Hedayati M. Comparison of various scoring methods for the diagnosis of protein-energy wasting in hemodialysis patients. Int Urol Nephrol. 2014;46:999–1004
  8. Hecking M, Bieber BA, Ethier J, Kautzky-Willer A, Sunder-Plassmann G, Säemann MD, et al. Sex-Specific Differences in Hemodialysis Prevalence and Practices and the Male-to-Female Mortality Rate: The Dialysis Outcomes and Practice Patterns Study (DOPPS). PLoS Med. 2014;11
  9. Nagai K, Matsuura M, Tsuchida K, Kanayama HO, Doi T, Minakuchi J. Prognostic factors for mortality in middle-aged and older hemodialysis patients: A 5-year observational study. J Artif Organs [Internet]. 2018 [cited 2021 Jun 18];21:94–101. Available from: https://pubmed.ncbi.nlm.nih.gov/28918555/
  10. Gomez AT, Kiberd BA, Royston JP, Alfaadhel T, Soroka SD, Hemmelgarn BR, et al. Comorbidity burden at dialysis initiation and mortality: A cohort study. Can J Kidney Heal Dis. 2015;2
  11. Leal VO, Stockler-Pinto MB, Farage NE, Aranha LN, Fouque D, Anjos LA, et al. Handgrip strength and its dialysis determinants in hemodialysis patients. 2011;
  12. Hecking M, Bieber BA, Ethier J, Kautzky-Willer A, Sunder-Plassmann G, Säemann MD, et al. Sex-Specific Differences in Hemodialysis Prevalence and Practices and the Male-to-Female Mortality Rate: The Dialysis Outcomes and Practice Patterns Study (DOPPS). PLoS Med [Internet]. 2014 [cited 2021 Jun 4];11. Available from: /pmc/articles/PMC4211675/
  13. 13. Ma HY, Chen S, Du Y. Estrogen and estrogen receptors in kidney diseases. Vol. 43, Renal Failure. 2021. p. 619–42
  14. Gluhovschi G, Gluhovschi A, Anastasiu D, Petrica L, Gluhovschi C, Velciov S. Chronic kidney disease and the involvement of estrogen hormones in its pathogenesis and progression. Rom J Intern Med. 2012;50:135–44
  15. Al Majarfi A, Al Salmi I, Metry AM, Al Ismaili F, Hola A, Hannawi S. Epidemiology of Patients at Initial Treatment with Hemodialysis. www.arcjournals.org ARC J Nephrol [Internet]. 2018;3:6–12. Available from: www.arcjournals.org
  16. Ikizler TA, Cano NJ, Franch H, Fouque D, Himmelfarb J, Kalantar-Zadeh K, et al. Prevention and treatment of protein energy wasting in chronic kidney disease patients: A consensus statement by the International Society of Renal Nutrition and Metabolism. Vol. 84, Kidney International. Nature Publishing Group; 2013. p. 1096–107
  17. Moreau-Gaudry X, Jean G, Genet L, Lataillade D, Legrand E, Kuentz F, et al. A simple protein-energy wasting score predicts survival in maintenance hemodialysis patients. J Ren Nutr. 2014;24:395–400
  18. Sood MM, Rigatto C, Komenda P, Mojica J, Tangri N. Mortality risk for women on chronic hemodialysis differs by age. Can J Kidney Heal Dis [Internet]. 2014 [cited 2021 Jun 18];1. Available from: /pmc/articles/PMC4349662/
  19. Ong-Ajyooth L, Vareesangthip K, Khonputsa P, Aekplakorn W. Prevalence of chronic kidney disease in Thai adults: A national health survey. BMC Nephrol [Internet]. 2009 [cited 2021 Feb 23];10:35. Available from: /pmc/articles/PMC2781792/
  20. Gorsane I, Mahfoudhi M, Younsi F, Helal I, Abdallah T Ben. Prevalence and Risk Factors of Hypertension in Hemodialysis. Open J Nephrol. 2015;05:54–60
  21. Hong W pyo, Lee YJ. The association of dialysis adequacy, body mass index, and mortality among hemodialysis patients. BMC Nephrol. 2019;20:1–8
  22. Prabhu R, Saraf K, Parkala B, Shenoy S, Nagaraju SP, Rangaswamy D, et al. HAND GRIP STRENGTH. IS IT A MARKER OF MALNUTRITION, OXIDATION STRESS, INFLAMMATION IN END STAGE KIDNEY DISEASE ON HEMODIALYSIS? Kidney Int Reports. 2019;4:S352
  23. Tian M, Zha Y, Li Q, Yuan J. Handgrip Strength and Mortality in Maintenance Hemodialysis Patients. Iran Red Crescent Med J. 2019;21
  24. Maigoda TC, Maisyorah E, Krisnasary A, Ardiansyah S. Energy, protein, and potassium intake with nutritional status among chronic renal failure patients undergoing hemodialysis in hospital Dr. M.Yunus, Bengkulu, Indonesia. Ann Trop Med Public Heal. 2020;23:1292–300
  25. Reiss J, Iglseder B, Kreutzer M, Weilbuchner I, Treschnitzer W, Kässmann H, et al. Case finding for sarcopenia in geriatric inpatients: Performance of bioimpedance analysis in comparison to dual X-ray absorptiometry. BMC Geriatr [Internet]. 2016 [cited 2020 May 11];16:52. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26928275
  26. Lok CE, Huber TS, Lee T, Shenoy S, Yevzlin AS, Abreo K, et al. KDOQI CLINICAL PRACTICE GUIDELINE FOR VASCULAR ACCESS: 2019 UPDATE. Am J Kidney Dis. 2020;75:S1–164

Last update:

No citation recorded.

Last update: 2025-01-06 20:12:08

No citation recorded.