Perbedaan Efek Paparan Pestisida Kimia dan Organik terhadap Kadar Glutation (GSH) Plasma pada Petani Padi

Ain Yuanita Insani; Ancah Caesarina Novi Marchianti; Septa Surya Wahyudi

doi:10.14710/jkli.17.2.63-67

DOI: https://doi.org/10.14710/jkli.17.2.63-67

Perbedaan Efek Paparan Pestisida Kimia dan Organik terhadap Kadar Glutation (GSH) Plasma pada Petani Padi

Ain Yuanita Insani , Ancah Caesarina Novi Marchianti, Septa Surya Wahyudi

University of Jember, Jember, Indonesia

BibTex Citation Data :

@article{JKLI17238,
author = {Ain Insani and Ancah Novi Marchianti and Septa Wahyudi},
title = {Perbedaan Efek Paparan Pestisida Kimia dan Organik terhadap Kadar Glutation (GSH) Plasma pada Petani Padi},
journal = {Jurnal Kesehatan Lingkungan Indonesia},
volume = {17},
number = {2},
year = {2018},
keywords = {chemical pesticides; organic pesticide; plasma glutathione (GSH)},
abstract = { Latar belakang: Serangan hama dan penyakit tanaman semakin meluas, sehingga para petani tidak dapat menghindari penggunaan pestisida kimia. Pestisida kimia bersifat polutan dan mengakibatkan terbentuknya radikal bebas yang dapat menyebabkan kerusakan organ. WHO memperkirakan ada 1,5 juta kasus keracunan pestisida terjadi pada pekerja di sektor pertanian. Tubuh membutuhkan antioksidan untuk menanggulangi radikal bebas akibat pestisida kimia. Salah satu antioksidan yang sering diukur untuk melihat dampak peningkatan radikal bebas adalah glutation(GSH). Penelitian ini bertujuan untuk mengetahui perbedaan efek paparan pestisida kimia dan organik terhadap kadar GSH plasma pada petani padi. Metode: Jenis penelitian yang digunakan adalah analitik observasional dengan rancangan penelitian cross sectional . Penelitian ini menggunakan sampel 30 orang, 15 orang petani organik di Desa Lombok Kulon Kecamatan Wonosari Kabupaten Bondowoso dan 15 orang petani anorganik di Desa Dawuhan Kecamatan Tenggarang Kabupaten Bondowoso. Pengambilan sampel darah dilakukan di vena mediana cubiti, selanjutnya dilakukan pengukuran kadar GSH plasma menggunakan metode Elman. Uji statistika dilakukan dengan menggunakan uji Unpaired T-test . Hasil: Hasil penelitian ini menunjukkan bahwa terdapat perbedaan yang signifikan antara kadar GSH plasma petani anorganik dan organik p<0.05. Petani anorganik memiliki rata-rata kadar GSH plasma lebih rendah dibandingkan dengan rata-rata kadar GSH plasma petani organik. Hal tersebut terjadi karena para petani anorganik mendapatkan paparan polutan berlebih dari zat-zat kimia dalam pestisida kimia sedangkan petani organik menggunakan bahan alami sehingga tidak menimbulkan residu dalam tubuh. Simpulan : Terdapat perbedaan yang signifikan antara kadar GSH plasma pada kelompok petani anorganik dan kelompok petani organik. Kadar GSH plasma petani anorganik lebih rendah dibandingkan dengan kadar GSH plasma petani organik. ABSTRACT Title: The Difference Effect of Chemical and Organic Pesticides Exposure to Plasma Glutathione (GSH) on Rice Farmers Background: Pests and plant diseases are widespread in agriculture so the use of chemical pesticides can not avoid. Pesticides are pollutants which forming free radicals and cause organ damage. WHO estimates that 1.5 million cases of pesticide poisoning occur in agricultural workers. The body needs antioxidant to cope free radicals due to chemical pesticides. GSH is one of antioxidants often measured to see the effects of increased free radicals in the body.This study aims to determine the differences effect of chemical and organic pesticide exposure on plasma glutathione (GSH) levels in rice farmers. Methods: The type of this research is observational analytics with cross sectional design. This study used 30 people as sample, 15 people organic farmers in the Desa Lombok Kulon, Kecamatan Wonosari, Bondowoso and 15 people inorganic farmers in Desa Dawuhan, Kec a matan Tenggarang, Bondowoso. Blood sampling was done in mediana cubiti vein, then measured of plasma GSH using Elman method. The statistical test was done by using Unpaired T-test. Results: The resulf of this research showed that there is a significant difference between plasma GSH level of inorganic farmer and organic farmer p <0.05. The average plasma GSH level of inorganic farmersare lower than average plasma GSH levels of organic farmers. This result is caused by excessive pollutants of chemicals contained in the pesticide exposed inorganic farmers while the group of organic farmers used natural ingredients in the pesticide so it did not makes residues in the body of farmers. Conclusion: Based on this, it is advisable for farmers to be more wise to use chemical pesticides in accordance with established rules and better recommended to replace the use of chemical pesticides with organic pesticides. },
issn = {2502-7085}, pages = {63--67} doi = {10.14710/jkli.17.2.63-67},
url = {https://ejournal.undip.ac.id/index.php/jkli/article/view/17238}
}

Citation Format:

Abstract

Latar belakang:Serangan hama dan penyakit tanaman semakin meluas, sehingga para petani tidak dapat menghindari penggunaan pestisida kimia. Pestisida kimia bersifat polutan dan mengakibatkan terbentuknya radikal bebas yang dapat menyebabkan kerusakan organ. WHO memperkirakan ada 1,5 juta kasus keracunan pestisida terjadi pada pekerja di sektor pertanian. Tubuh membutuhkan antioksidan untuk menanggulangi radikal bebas akibat pestisida kimia. Salah satu antioksidan yang sering diukur untuk melihat dampak peningkatan radikal bebas adalah glutation(GSH). Penelitian ini bertujuan untuk mengetahui perbedaan efek paparan pestisida kimia dan organik terhadap kadar GSH plasma pada petani padi.

Metode:Jenis penelitian yang digunakan adalah analitik observasional dengan rancangan penelitiancross sectional. Penelitian ini menggunakan sampel 30 orang, 15 orang petani organik di Desa Lombok Kulon Kecamatan Wonosari Kabupaten Bondowoso dan 15 orang petani anorganik di Desa Dawuhan Kecamatan Tenggarang Kabupaten Bondowoso. Pengambilan sampel darah dilakukan di vena mediana cubiti, selanjutnya dilakukan pengukuran kadar GSH plasma menggunakan metode Elman. Uji statistika dilakukan dengan menggunakan uji Unpaired T-test.

Hasil:Hasil penelitian ini menunjukkan bahwa terdapat perbedaan yang signifikan antara kadar GSH plasma petani anorganik dan organik p<0.05. Petani anorganik memiliki rata-rata kadar GSH plasma lebih rendah dibandingkan dengan rata-rata kadar GSH plasma petani organik. Hal tersebut terjadi karena para petani anorganik mendapatkan paparan polutan berlebih dari zat-zat kimia dalam pestisida kimia sedangkan petani organik menggunakan bahan alami sehingga tidak menimbulkan residu dalam tubuh.

Simpulan: Terdapat perbedaan yang signifikan antara kadar GSH plasma pada kelompok petani anorganik dan kelompok petani organik. Kadar GSH plasma petani anorganik lebih rendah dibandingkan dengan kadar GSH plasma petani organik.

ABSTRACT

Title: The Difference Effect of Chemical and Organic Pesticides Exposure to Plasma Glutathione (GSH) on Rice Farmers

Background: Pests and plant diseases are widespread in agriculture so the use of chemical pesticides can not avoid. Pesticides are pollutants which forming free radicals and cause organ damage. WHO estimates that 1.5 million cases of pesticide poisoning occur in agricultural workers. The body needs antioxidant to cope free radicals due to chemical pesticides. GSH is one of antioxidants often measured to see the effects of increased free radicals in the body.This study aims to determine the differences effect of chemical and organic pesticide exposure on plasma glutathione (GSH) levels in rice farmers.

Methods: The type of this research is observational analytics with cross sectional design. This study used 30 people as sample, 15 people organic farmers in the Desa Lombok Kulon, Kecamatan Wonosari, Bondowoso and 15 people inorganic farmers in Desa Dawuhan, Kecamatan Tenggarang, Bondowoso. Blood sampling was done in mediana cubiti vein, then measured of plasma GSH using Elman method. The statistical test was done by using Unpaired T-test.

Results: The resulf of this research showed that there is a significant difference between plasma GSH level of inorganic farmer and organic farmer p <0.05. The average plasma GSH level of inorganic farmersare lower than average plasma GSH levels of organic farmers. This result is caused by excessive pollutants of chemicals contained in the pesticide exposed inorganic farmers while the group of organic farmers used natural ingredients in the pesticide so it did not makes residues in the body of farmers.

Conclusion: Based on this, it is advisable for farmers to be more wise to use chemical pesticides in accordance with established rules and better recommended to replace the use of chemical pesticides with organic pesticides.

Fulltext View|Download

Keywords: chemical pesticides; organic pesticide; plasma glutathione (GSH)

Article Metrics:

Article Info

Section: Research Articles

Language : EN

In Vol 17, No 2 (2018): Oktober 2018

Recent articles

Pengaruh Iklim Terhadap Peluang Umur Nyamuk Mansonia spp di Daerah Endemis Filariasis di Kabupaten Kapuas Analisis Paparan Kadmium, Besi, Dan Mangan Pada Air Terhadap Gangguan Kulit Pada Masyarakat Desa Ibul Besar Kecamatan Indralaya Selatan Kabupaten Ogan Ilir Pengaruh Kebisingan Terhadap Tekanan Darah dan Nadi pada Pekerja Pabrik Kayu PT. Muroco Jember Halaman Belakang Halaman Sampul More recent articles

Most cited articles

Analisis Faktor-Faktor Yang Berhubungan Dengan Keracunan Merkuri Pada Penambang Emas Tradisional di Desa Jendi Kecamatan Selogiri Kabupaten Wonogiri Halaman Belakang Analisis Faktor Risiko Keracunan Pestisida Organofosfat Pada Keluarga Petani Hortikultura di Kecamatan Ngablak Kabupaten Magelang Pengaruh Tingkat Pengetahuan dan Sikap Ibu terhadap Penyakit Kecacingan Pada Balita Faktor-Faktor Lingkungan dan Perilaku Yang Berhubungan dengan Kejadian Filariasis di Kabupaten Bangka Barat More cited articles

Kumar LP, Panneerselvam N. Toxic Effects of Pesticides: A Review on Cytogenetic Biomonitoring Studies. Medicine and Biology. 2008, 15(2): 46-50
Surajudeen YA, Sheu RK, Ayokulehin KM, Olatunbosun AG. Oxidative stress indices in Nigerian pesticide applicators and farmers occupationally exposed to organophosphate pesticides. International Journal of Applied and Basic Medical Research. 2014, 4(1):37-41
Main PAE, Angley MT, O’Doherty CE, Thomas P, Fenech M. The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis.Nutrition and Metabolism 2012, 9: 35
Kalpravidh RW, Tangjaidee T, Hatairaktham S, Charoensakdi R, Panichkul N, Siritanaratkul N, and Fucharoen, S. Glutathione Redox System in β-Thalassemia/Hb E Patients. The Scientific World Journal 2013:1-7
Khan H, Khan MF, Khan BA, Wahab A, Jan SU, Mukhtair M, Ullah N, Haque N, Farid A. Oxidation of glutathione (GSH) in blood plasma due to oxidative stressors: A case study of silver. Journal of Pharmacy and Pharmacology 2012, 6(21): 1502-1507
Birben E, Sahiner UM.,Sackesen C,Erzurum S, dan Kalayci, O. Oxidative Stress and Antioxidant Defense.WAO Journal 2012, 5:9-19
Adesanoye, OA, Farombi EO. In Vitro Antioxidant Properties of Methanolic Leaf Extract of Vernonia Amygdalina Del. Niger J Physiol Sci 2014, 29: 91-101
Hinkley GK, Roberts SM. Insecticides and Herbicides. Springer International Publishing Switzerland. 2015
Chen W, Jia Z, Pan MH, Babu PVA. Natural Products for the Prevention of Oxidative Stress-Related Diseases: Mechanisms and Strategies. Oxidative Medicine and Cellular Longevity 2015-2016: 2
Sharma RK, Upadhyay G, Shiddiqi NJ, Sharma B. Pesticides-induced biochemicalalterations in occupational NorthIndian suburban population. Human and Experimental Toxicology 2013: 1-15
Rastogi SK, Satyanarayan PVV, Ravishankar D, Tripathi SA. Study on oxidative stress and antioxidant status of agricultural workers exposed to organophosphorus insecticides during spraying. Indian Journal of Occupational and Environmental Medicine 2009 Desember; 13(3): 131-134

Last update:

Sosialisasi Pestisida Nabati Ramah Lingkungan Di Desa Joho, Kabupaten Kediri
Devina Cinantya Anindita, Tutut Dwi Sutiknjo, Rena Eksa Pawani. JATIMAS : Jurnal Pertanian dan Pengabdian Masyarakat, 3 (2), 2023. doi: 10.30737/jatimas.v3i2.5115

Last update: 2024-11-20 07:31:57

No citation recorded.

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Jurnal Kesehatan Lingkungan Indonesia (JKLI, p-ISSN: 1412-4939, e-ISSN:2502-7085) and Master Program of Environmental Health, Diponegoro University as the publisher of the journal. Copyright encompasses the rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms, and any other similar reproductions, as well as translations.

JKLI journal and Master Program of Environmental Health, Diponegoro University, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the JKLI journal are the sole and exclusive responsibility of their respective authors and advertisers.

The Copyright Transfer Form can be downloaded here: [Copyright Transfer Form JKLI journal]
The copyright form should be signed originally and send to the Editorial Office in the form of original mail or scanned document to jkli@live.undip.ac.id.