skip to main content

Ion-exchange Resin Catalyzed Esterification of Lactic Acid with Isopropanol: a Kinetic Study

*Amrit P. Toor  -  University Institute of Chemical Engineering and Technology, Panjab University, Chandigarh-160014, India
Mamta Sharma  -  University Institute of Chemical Engineering and Technology, Panjab University, Chandigarh-160014, India
Sakshi Thakur  -  University Institute of Chemical Engineering and Technology, Panjab University, Chandigarh-160014, India
Ravinder K. Wanchoo  -  University Institute of Chemical Engineering and Technology, Panjab University, Chandigarh-160014, India

Citation Format:

The kinetic behavior of esterification of lactic acid with isopropanol over an acidic cation exchange resin, Amberlyst 15, was studied under isothermal condition. Isopropyl lactate synthesized in this reaction is an important pharmaceutical intermediate. The experiments were carried out in a stirred batch reactor in the temperature range of 323.15 to 353.15 K. The effect of various parameters such as temperature, molar ratio and catalyst loading was studied. Variation in parameters on rate of reaction demonstrated that the reaction was intrinsically controlled. Kinetic modeling was performed using Eley-Rideal model which acceptably fits the experimental data. The activation energy was found to be 22.007 kJ/mol and frequency factor was 0.036809 l2 g-1 mol-1 min-1 for forward reaction. The value of entropy for the forward reaction was found to be 182.317 J K-1 mol-1 . © 2011 BCREC UNDIP. All rights reserved

(Received: 19th January 2011, Revised: 16th March 2011; Accepted: 16th March 2011)

[How to Cite: A.P. Toor, M. Sharma, S. Thakur, and R. K. Wanchoo. (2011). Ion-exchange Resin Catalyzed Esterification of Lactic Acid with Isopropanol: a Kinetic Study. Bulletin of Chemical Reaction Engineering and Catalysis, 6(1): 39-45. doi:10.9767/bcrec.6.1.791.39-45]

[How to Link / DOI: || or local: ]

| View in 


Fulltext View|Download
Keywords: Heterogeneous catalysis; Esterification; Lactic acid: Ion exchange resin; Amberlyst 15;

Article Metrics:

  1. Carey, F., Sundberg. R., 1990., Reaction and synthesis: Advanced Organic Chemistry, 3rd Edition, New York
  2. Phalak, C. A., 2004, Reaction Engineering studies in ion exchange resin catalyzed esterification reactions”, Thesis submitted to National chemical Laboratory, Pune, India
  3. Yadav,G.D., Kulkarni, H.B., 2000, Ion exchange resin catalysis in the synthesis of isopropyl lactate, Reactive Function Polymer, 44:153-165. [" target="_blank">CrossRef]
  4. Alime,I., Hosgun L., 2007, Kinetics of synthesis of isobutyl propionate over amberlyst 15, Turkish Journal of Chemistry, 31: 493-499
  5. Mcketta, J., 2002 Encyclopedia of Chemical Processing and Design”, CRC Press LLC,69:262
  6. Ayyappan,K.R.,Toor.A.P., Gupta R., Bansal A., Wanchoo R.K., 2009, Catalystic hydrolysis of Ethyl Acetate using cation exchange resin (Amberlyst 15) : A kinetic study”, Bulletin of Chemical Reaction Engineering & Catalysis, 4:16-22. [" target="_blank">CrossRef]
  7. Shanmugam, S., Viswanathan, B., Varadarajan, T.K. (2004). Esterification by solid acid catalysts - A comparison. Journal of Molecular Catalysis A: Chemical, 223 (1-2): 143-147. [" target="_blank">CrossRef]
  8. Ma, F.R., Hana, M.A., 1999, Biodiesel production: a review, Bioresource Technology, 70:1-15. [" target="_blank">CrossRef]
  9. Gelbard, G., 2005, Organic Synthesis by Catalysis with Ion-Exchange Resins”, Industrial & Engineering Chemistry Research, 44(23): 8468-8498. [" target="_blank">CrossRef]
  10. Mazzotti, M., Neri, B., Gelosa, D., Kruglov, A., Morbidelli, M., 1997, Kinetics of Liquid-Phase Esterification Catalyzed by Acidic Resins, Industrial & Engineering Chemistry Research, 36(1):3-10. [" target="_blank">CrossRef]
  11. Pöpken,T., Götze, L., Gmehling, J., 2000, Reaction Kinetics and Chemical Equilibrium of Homogeneously and Heterogeneously Catalyzed Acetic Acid Esterification with Methanol and Methyl Acetate Hydrolysis, Industrial & Engineering Chemistry Research, 39(7):2601-2611. [" target="_blank">CrossRef]
  12. Lee, M. -J., Chiu, J.-Y., Lin, H., 2002, Kinetics of Catalytic Esterification of Propionic Acid and n-Butanol over Amberlyst 35, Industrial & Engineering Chemistry Research, 41(12):2882-2887. [" target="_blank">CrossRef]
  13. Lee, M.-J., Wu, H.-T., Lin, H., 2000, Kinetics of Catalytic Esterification of Acetic Acid and Amyl Alcohol over Dowex, Industrial & Engineering Chemistry Research, 39( 11):4094-4099. [" target="_blank">CrossRef]
  14. Alexandratos, S.D., 2009, Ion-Exchange Resins: A Retrospective from Industrial & Engineering Chemistry Research, Industrial & Engineering Chemistry Research, 48(1): 388-398. [" target="_blank">CrossRef]
  15. Teresa, W., Miroslaw, G., Jerzy S., Mariusz,W., 2010, Liquid –phase esterification of methacrylic acid with methanol catalyzed by heteropolyacids, International Journal of Chemical Reactor Engineering, 8: A68
  16. Altiokka, M.R., Çitak, A. (2003). Kinetics study of esterification of acetic acid with isobutanol in the presence of amberlite catalyst. Applied Catalysis A: General, 239 (1-2): 141-148. [" target="_blank">CrossRef]
  17. Sanz, M.T, Murga, R, Beltran, S., 2002, Recovery of lactic acid by batch reactive distillation, Industrial & Engineering Chemistry Research, 41:512-517. [" target="_blank">CrossRef]
  18. Delgado, P., Sanz, M.T., Beltrán, S., 2007, Kinetic study for esterification of lactic acid with ethanol and hydrolysis of ethyl lactate using an ion-exchange resin catalyst, Chemical Engineering Journal, 126:111-118. [" target="_blank">CrossRef]
  19. Zhang, Y., Yang, Ma L., 2004, Kinetics of Esterification of lactic acid with Ethanol catalyzed by cation-exchange resins, Reactive Functional Polymer, 61:101-114. [" target="_blank">CrossRef]
  20. Darge, O., Thyrion, F.C., 1993, Kinetics of the liquid phase synthesis and hydrolysis of butyl lactate catalysed by cation exchange resin, Journal of Chemical Technology and Biotechnology, 58:351-357 . [" target="_blank">CrossRef]
  21. Liu, W.T., Tan, C.S., 2001, Liquid-phase esterification of propionic acid with n-butanol, Industrial & Engineering Chemistry Research, 44:3281–3286. [" target="_blank">CrossRef]
  22. Choi, J.I., Hong, W.H., Chang, H.N., 1996, Reactions Kinetics of Lactic Acid with Methanol Catalyzed by Acid Resins”, International Journal of Chemical Kinetics, 28:37-41. [;2-N" target="_blank">CrossRef]
  23. Yadav, G.D., Thathagar, M.B., 2002, Esterification of Maleic acid with Ethanol over cation exchange resin catalysts, Reactive Functional Polymer, 52:99-100 [" target="_blank">CrossRef]

Last update:

No citation recorded.

Last update:

No citation recorded.