1Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro/ RSUP Dr. Kariadi, Indonesia
2Semarang, Indonesia
BibTex Citation Data :
@article{JAI6458, author = {Rezka Trisnanto and Uripno Budiono and Widya Nurcahyo}, title = {Lama Analgesia Lidokain 2% 80 mg Dibandingkan Kombinasi Lidokain 2% dan Epinefrin pada Blok Subarakhnoid}, journal = {JAI (Jurnal Anestesiologi Indonesia)}, volume = {2}, number = {3}, year = {2010}, keywords = {blok subarakhnoid; lidokain 2% 80 mg; epinefrin 0,02 mg}, abstract = { Background: Subarachnoid block using isobaric lidocaine, has been applied on many variable clinic surgeries. In the country, lidocaine 2% 80 mg is preferable because of its cost The disadvantage of using lidocaine 2% 80 cc is short duration, 45 - 60 minutes, despite many surgeries take more than 1 hour, despite many surgeries take more than 1 hour. Objective: to prove whether addition of epinephrine 0.02 mg on subarachnoiod block with lidocaine 2% 80 cc able to make longer time of analgesia. Methods: It is a experimental study with quota sampling design on the 52 patients, which are undergoing surgery. In the room, blood pressure (BP), heart rate (HR), respiratory rate (RR) were measured. All of the patients were fasting 6 hour and no premedications. In the Central Operating Room/ COT (\"Instalasi Bedah Sentral / IBS\") vein access 18 G was inserted and colloid 7.5 cc/KgBW given as preload. The patients were divided randomly into 2 groups, lidocaine group and lidocaine - epinephrine group. Motoric block evaluation was performed on the same time with level of analgesia evaluation by using Bromage's criteria. Blood pressure, MAP, heart rate, respiratory rate were measured before and after subarachnoid block, in the first 10 minutes of surgery, measurement every minute, 20 th minute and every 10 minute, 20 th minute and then every 10 minute until there was no motoric block. Uncooperative patient and who need additional analgesia during surgery, was excluded. Using Mann - Whitney and p < 0.05. Data were gathered in tables. Results: There was no difference for patients characteristics and surgery distribution among 2 groups. Regression time of 2 segments on the lidocaine -epinephrine group was longer significantly than iidocaine group (p = 0.000). The onset of sensoric block on lidocaine was shorter significantly than lidocaine -epinephrine group (p = 0.025). Duration of motoric block on lidocaine -epinephrine group was longer significantly than lidocaine group (p = 0.000). There was no significant difference on maximal level in two groups. There was no difference significantly on BP, MAP, HR after preload. There was difference significantly on HR at 1 st and 2 nd during subarachnoid block given between two group. Side effect distribution had difference significantly. Conclusion: Regression time of 2 segments on iidocaine - epinephrine group was longer significantly than lidocaine group. Keywords : subarachnoid block, lidocaine 2% 80 mg, epinephrine 0.02 mg ABSTRAK Latar belakang: Blok subarakhnoid menggunakan lidokain isobarik, banyak digunakan pada operas! untuk pasien dengan berbagai kondisi klinik. Di daerah banyak digunakan lidokain 2% 80 mg dikarenakan harganya yang relatif murah. Kerugian dari penggunaan lidokain 2% 80 mg adalah durasi yang singkat, yaitu antara 45 - 60 menit, padahal banyak tindakan pembedahan yang durasinya lebih dari 1 jam. Tujuan: Membuktikan apakah penambahan epinefrin 0,02 mg pada blok subarakhnoid dengan lidokain 2% 80 mg dapat memperpanjang lama analgesia. Metode : Merupakan penelitian eksperimental dengan desain quota sampling pada 52 pasien yang menjalani operasi di daerah region abdominal dengan blok subarakhnoid. Saat di ruangan dilakukan pengukuran tekanan darah, laju jantung, dan laju nafas. Semua penderita dipuasakan 6 jam dan tidak diberikan obat premedikasi. Penilaian blok motorik dilakukan pada saat yang sama dengan penilaian level analgesi dengan menggunakan criteria dari Bromage. Penilaian tekanan darah, TAR, laju jantung dan laju nafas dilakukan sebelum dan sesudah blok subarakhnoid selama 10 menit pertama pembedahan dilakukan tiap menit, menit ke 15,20 selanjutnya setiap 10 menit sampai hilangnya blok motorik. Pasien tidak kooperatif dan membutuhkan analgetik tambahan selama pembedahan dikeluarkan dari penelitian. Uji statistik menggunakan Mann - Whitney dan derajat kemaknaan p < 0,05. Penyajian data dalam bentuk tabel. Hasil: Karakteristik penderita dan distribusi operasi antara kedua kelompok tidak berbeda. Waktu regresi dua segmen kelompok lidokain - epinefrin lebih lama dibandingkan kelompok lidokain (p=0,000). Mula kerja blok sensorik kelompok lidokain lebih cepat dibandingkan dengan kelompok lidokain - epinefrin (pK),002). Mula kerja blok motorik kelompok lidokain lebih cepat dibandingkan dengan kelompok lidokain - epinefrin (/7= : 0,025). Lama kerja blok motorik kelompok lidokain - epinefrin lebih panjang dibandingkan dengan kelompok lidokain (p=0,000). Level maksimal blok sensorik tidak terdapat perbedaan bermakna pada kedua kelompok. TDS, TDD, TAR, laju nafas pada keadaan hemodinamik setelah preload tidak terdapat perbedaan bermakna pada kedua kelompok. Pada laju jantung terdapat perbedaan bermakna antara kedua kelompok (p=0,013). TDS, TDD, TAR, laju nafas selama blok subarakhnoid tidak terdapat perbedaan bermakna pada kedua kelompok. Laju jantung terdapat perbedaan bermakna pada menit pertama dan menit kedua selama blok subarakhnoid pada kedua kelompok. Distribusi efek samping terdapat perbedaan bermakna antara Kesimpulan: Waktu regresi 2 segmen kelompok lidokain - epinefrin lebih lama secara bermakna dibandingkan kelompok lidokain. Kata kunci : Blok subarakhnoid, lidokain 2% 80 mg, epinefrin 0,02 mg. }, issn = {2089-970X}, doi = {10.14710/jai.v2i3.6458}, url = {https://ejournal.undip.ac.id/index.php/janesti/article/view/6458} }
Refworks Citation Data :
Background: Subarachnoid block using isobaric lidocaine, has been applied on many variable clinic surgeries. In the country, lidocaine 2% 80 mg is preferable because of its cost The disadvantage of using lidocaine 2% 80 cc is short duration, 45 - 60 minutes, despite many surgeries take more than 1 hour, despite many surgeries take more than 1 hour.
Objective: to prove whether addition of epinephrine 0.02 mg on subarachnoiod block with lidocaine 2% 80 cc able to make longer time of analgesia.
Methods: It is a experimental study with quota sampling design on the 52 patients, which are undergoing surgery. In the room, blood pressure (BP), heart rate (HR), respiratory rate (RR) were measured. All of the patients were fasting 6 hour and no premedications. In the Central Operating Room/ COT ("Instalasi Bedah Sentral / IBS") vein access 18 G was inserted and colloid 7.5 cc/KgBW given as preload. The patients were divided randomly into 2 groups, lidocaine group and lidocaine - epinephrine group. Motoric block evaluation was performed on the same time with level of analgesia evaluation by using Bromage's criteria. Blood pressure, MAP, heart rate, respiratory rate were measured before and after subarachnoid block, in the first 10 minutes of surgery, measurement every minute, 20 th minute and every 10 minute, 20 th minute and then every 10 minute until there was no motoric block. Uncooperative patient and who need additional analgesia during surgery, was excluded. Using Mann - Whitney and p < 0.05. Data were gathered in tables.
Results: There was no difference for patients characteristics and surgery distribution among 2 groups. Regression time of 2 segments on the lidocaine -epinephrine group was longer significantly than iidocaine group (p = 0.000). The onset of sensoric block on lidocaine was shorter significantly than lidocaine -epinephrine group (p = 0.025). Duration of motoric block on lidocaine -epinephrine group was longer significantly than lidocaine group (p = 0.000). There was no significant difference on maximal level in two groups. There was no difference significantly on BP, MAP, HR after preload. There was difference significantly on HR at 1 st and 2 nd during subarachnoid block given between two group. Side effect distribution had difference significantly.
Conclusion: Regression time of 2 segments on iidocaine - epinephrine group was longer significantly than lidocaine group.
Keywords : subarachnoid block, lidocaine 2% 80 mg, epinephrine 0.02 mg
ABSTRAK
Latar belakang: Blok subarakhnoid menggunakan lidokain isobarik, banyak digunakan pada operas! untuk pasien dengan berbagai kondisi klinik. Di daerah banyak digunakan lidokain 2% 80 mg dikarenakan harganya yang relatif murah. Kerugian dari penggunaan lidokain 2% 80 mg adalah durasi yang singkat, yaitu antara 45 - 60 menit, padahal banyak tindakan pembedahan yang durasinya lebih dari 1 jam.
Tujuan: Membuktikan apakah penambahan epinefrin 0,02 mg pada blok subarakhnoid dengan lidokain 2% 80 mg dapat memperpanjang lama analgesia.
Metode : Merupakan penelitian eksperimental dengan desain quota sampling pada 52 pasien yang menjalani operasi di daerah region abdominal dengan blok subarakhnoid. Saat di ruangan dilakukan pengukuran tekanan darah, laju jantung, dan laju nafas. Semua penderita dipuasakan 6 jam dan tidak diberikan obat premedikasi. Penilaian blok motorik dilakukan pada saat yang sama dengan penilaian level analgesi dengan menggunakan criteria dari Bromage. Penilaian tekanan darah, TAR, laju jantung dan laju nafas dilakukan sebelum dan sesudah blok subarakhnoid selama 10 menit pertama pembedahan dilakukan tiap menit, menit ke 15,20 selanjutnya setiap 10 menit sampai hilangnya blok motorik. Pasien tidak kooperatif dan membutuhkan analgetik tambahan selama pembedahan dikeluarkan dari penelitian. Uji statistik menggunakan Mann - Whitney dan derajat kemaknaan p < 0,05. Penyajian data dalam bentuk tabel.
Hasil: Karakteristik penderita dan distribusi operasi antara kedua kelompok tidak berbeda. Waktu regresi dua segmen kelompok lidokain - epinefrin lebih lama dibandingkan kelompok lidokain (p=0,000). Mula kerja blok sensorik kelompok lidokain lebih cepat dibandingkan dengan kelompok lidokain - epinefrin (pK),002). Mula kerja blok motorik kelompok lidokain lebih cepat dibandingkan dengan kelompok lidokain - epinefrin (/7= : 0,025). Lama kerja blok motorik kelompok lidokain - epinefrin lebih panjang dibandingkan dengan kelompok lidokain (p=0,000). Level maksimal blok sensorik tidak terdapat perbedaan bermakna pada kedua kelompok. TDS, TDD, TAR, laju nafas pada keadaan hemodinamik setelah preload tidak terdapat perbedaan bermakna pada kedua kelompok. Pada laju jantung terdapat perbedaan bermakna antara kedua kelompok (p=0,013). TDS, TDD, TAR, laju nafas selama blok subarakhnoid tidak terdapat perbedaan bermakna pada kedua kelompok. Laju jantung terdapat perbedaan bermakna pada menit pertama dan menit kedua selama blok subarakhnoid pada kedua kelompok. Distribusi efek samping terdapat perbedaan bermakna antara
Kesimpulan: Waktu regresi 2 segmen kelompok lidokain - epinefrin lebih lama secara bermakna dibandingkan kelompok lidokain.
Kata kunci : Blok subarakhnoid, lidokain 2% 80 mg, epinefrin 0,02 mg.
Article Metrics:
Last update:
Last update: 2024-12-09 01:22:36
The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to JAI (Jurnal Anestesiologi Indonesia) and Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University as publisher of the journal. Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms, and any other similar reproductions, as well as translations.
JAI (Jurnal Anestesiologi Indonesia) and Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University and the Editors make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in JAI (Jurnal Anestesiologi Indonesia) are the sole and exclusive responsibility of their respective authors and advertisers.
The Copyright Transfer Form can be downloaded here:[Copyright Transfer Form JAI]. The copyright form should be signed originally and send to the Editorial Office in the form of original mail, scanned document:
Mochamat (Editor-in-Chief)
Editorial Office of JAI (Jurnal Anestesiologi Indonesia)
Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/ Dr. Kariadi General Hospital Medical Center (RSUP Dr. Kariadi)
Jl. Dr. Soetomo No. 16 Semarang, Central Java, Indonesia, 50231
Telp. : (024) 8444346
Email : janestesiologi@gmail.com
View My Stats
This work is licensed under a Creative Commons Attribution 4.0 International License