Perbandingan Efektivitas Premedikasi MgSO4 40 mg/Kgbb dengan Klonidin 1 mcg/Kgbb Intravena sebagai Ajuvan untuk Teknik Hipotensi Kendali pada Bedah Sinus Endoskopik Fungsional
Tujuan: Membandingkan efektivitas premedikasi MgSO4 40 mg/kgBB dengan Klonidin 1 mcg/kgBB intravena sebagai ajuvan teknik hipotensi kendali pada bedah sinus endoskopik fungsional pada anestesi umum.
Metode: Penelitian eksperimental secara acak tersamar tunggal. Total sampel 48 orang yang menjalani bedah sinus endoskopik fungsional. Sampel dibagi dalam dua kelompok perlakuan, kelompok pertama diberikan premedikasi MgSO4 40 mg/kgBB (n=24) dan kelompok kedua diberikan Klonidin 1 mcg/kgBB (n=24). Selama periode hipotensi kendali, setiap 15 menit ahli THT memberikan penilaian numerik dari kondisi lapangan operasi menggunakan skala Fromme dan Boezzart. Data non parametrik diuji dengan uji Mann-Whitney.
Hasil: Tampilan lapangan pandang operasi pada bedah sinus endoskopik fungsional pada kedua kelompok tidak berbeda bermakna (p>0,05)
Simpulan: Premedikasi MgSO4 40 mg/kgBB intravena sama efektif dengan Klonidin 1 mcg/kgBB sebagai ajuvan dalam teknik hipotensi kendali dan memberikan tampilan lapangan operasi yang bersih pada bedah sinus endoskopik fungsional.
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