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Effect of Coloading Ringer's Lactate on Blood Pressure Stability in Patients with Spinal Anesthesia

Universitas Bhakti Kencana Bandung, Indonesia

Available online: 26 Aug 2025.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

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Abstract

Background: The most common hemodynamic complication associated with spinal anesthesia is hypotension, hence the need for fluid coloading.

Objective: The purpose of this study was to determine the effect of lactated ringer coloading fluid on blood pressure stability.

Methods: This study was conducted using quantitative method with quasi-experimental with one group pre test post test design. The research instrument used an initial blood pressure observation sheet, blood pressure after spinal anesthesia and after giving lactated ringer coloading with a calculation of 10 cc / kg of patient weight. The population in this study were all patients who underwent spinal anesthesia and the sample of this study amounted to 60 respondents with non probability sampling technique with purposive sampling. Data analysis in this study used univariate and bivariate analysis. This study has carried out data normality tests and research ethics. Bivariate analysis in this study used Paired t-test.

Results: The results showed that after spinal anesthesia most (51.7%) patients had hypotension. After being given lactated ringer coloading, most patients (68.3%) had normal blood pressure. Systole blood pressure increased by 9,750 mmHg and disatole also increased by 6,500 mmHg.

Conclusion: The conclusion of this study is the effect of lactated ringer coloading on blood pressure stability with a value of 0.000.

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Keywords: blood pressure; coloading; hypotension; lactated ringer; spinal anesthesia

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  1. Setijanto E, Thamri H, Caprianus AR. Perbandingan antara Mobilisasi Cepat dan Mobilisasi Lambat terhadap Komplikasi Neurologis pada Pasien Anestesi Spinal. J Anestesi Perioper. 2022;10(1):29–34
  2. Made Artawan I, Sarim BY, Sagita S, Dedi MAE. Comparison the effect of preloading and coloading with crystalloid fluid on the incidence of hypotension after spinal anesthesia in cesarean section. Bali J Anesthesiol. 2020;4(1):3–7
  3. Quarshie A, Anno A, Djagbletey R, Sarpong P, Sottie D, Phillips BJ, et al. Comparison of Crystalloid Preloading and Coloading for Prevention of Spinal-induced Hypotension in Cesarean Delivery: A Randomized Controlled Trial at a Tertiary Facility in Ghana. Open Access Maced J Med Sci. 2023;11(B):627–33
  4. Hassan B, Abdel-Azim R, Abdel-Hamid D, Farag S, Toulan H. a Comparative Study Between the Effect of Pre-Load Colloid and Co-Load Crystalloid Administration on Blood Pressure After Spinal Anesthesia in Elective Cesarean Delivery. Ain Shams Med J. 2020;71(2):305–16
  5. Gupta B, Ghosh A, Ray A, Haldar P, Piplai G. Comparative Study between Ringer’s Lactate and Gelofusine as Preloading Infusion in Spinal Anaesthesia for Prevention of Hypotension. J Coll Med Sci. 2021;17(4):360–7
  6. Supraptomo. Manajemen Anestesi Subarachnoid Block pada Pasien dengan Impending Eklampsia. J Anestesi Obstet Indones. 2020;3(1)
  7. Hafiduddin M, Febianita F, Nabhani N. Hubungan Antara Preloading Cairan Kristaloid dengan Status Tekanan Darah Intra Anestesi Spinal. J Ners. 2023;7(2):1437–43
  8. Zahid TR, Farooq U, Waraich AA, Bashir R, Ali I. Effect of Crystalloid Administration Timing on Hypotension in Spinal Anesthesia for Cesarean Delivery : Preload Versus Coload : A Study at a Tertiary Care Hospital in Rawalpindi. 2024;5(4):491–6
  9. Isngadi I. Vasopressor Pilihan Untuk Anestesi Obstetri. J Anestesi Obstet Indones. 2024;7(1):54–62
  10. Chandraningrum AR, Supraptomo RT, Laqif A. Perbandingan Hipotensi Antara Anestesi General dan Anestesi Spinal pada Seksio Sesarea. Plex Med J. 2022;1(5):172–80
  11. Hofhuizen C, Lemson J, Snoeck M, Scheffer GJ. Spinal anesthesia-induced hypotension is caused by a decrease in stroke volume in elderly patients. Local Reg Anesth. 2019;12:19–26
  12. Dwiputra AG. Komplikasi Pasca Anestesia Spinal: Apa saja yang harus kita waspadai? Maj Anest Crit Care. 2023;41(1):1–3
  13. Wong CA. Spinal anesthesia-induced hypotension: is it more than just a pesky nuisance? Am J Obstet Gynecol [Internet]. 2020;223(5):621–3. Available from: https://doi.org/10.1016/j.ajog.2020.08.105
  14. Fukuda N, Katakawa M, Ito H, Hara T, Otsuka N, Ishizuka M, et al. 5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. J Pharmacol Sci [Internet]. 2023;152(1):22–9. Available from: https://doi.org/10.1016/j.jphs.2023.02.007
  15. Puspitasari P, Lukitasari D, Khalilati N, Suryani RL, Sukmaningtyas W, Ainurrahmah Y, et al. Pemenuhan Kebutuhan Dasar Manusia 1. 1st ed. Noprianty R, editor. Magelang: PT. ADIKARYA PRATAMA GLOBALINDO; 2023. 173 p
  16. Noprianty R, Wahyudi FM, Valiani C. Pemenuhan Kebutuhan Dasar Manusia II. 1st ed. I Made Sukma Wijaya, editor. Bandung: Media Sains Indonesia; 2023
  17. Fitzgerald JP, Fedoruk KA, Jadin SM, Carvalho B, Halpern SH. Prevention of hypotension after spinal anaesthesia for caesarean section: a systematic review and network meta-analysis of randomised controlled trials. Anaesthesia. 2020;75(1):109–21
  18. Trisandi MM, Rohmah AN, Rosidah I. Pengaruh Pemberian Preloading Cairang terhadap Tekanan Darah pada Pasien Spinal Anestesi. J Borneo Cendekia. 2024;8(1):20–9
  19. Borse DYM, Patil DAP, Subhedar DRD, Sangale DSV. Comparative study of preloading and Co-loading with ringer lactate for prevention of spinal hypotension in elective cesarean section. Int J Med Anesthesiol. 2020;3(1):30–2
  20. Pranandaru A, Sebayang SM, Yudono DT. Pengaruh Coloading Terhadap Perubahan Kenaikan Tekanan Darah Pada Pasien Spinal Anestesi 2024 Madani : Jurnal Ilmiah Multidisipline. Madani J Ilm Multidisiplin. 2024;2(9):24–31
  21. Min JY, Chang HJ, Kim SJ, Cha SH, Jeon JP, Kim CJ, et al. Prediction of hypotension during the alveolar recruitment maneuver in spine surgery: a prospective observational study. Eur J Med Res [Internet]. 2023;28(1):1–8. Available from: https://doi.org/10.1186/s40001-023-01031-8

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