DOI: https://doi.org/10.14710/jgi.7.1.49-53

Biskuit mocaf–garut tinggi zat besi meningkatkan kadar Fe darah dan kadar hemoglobin pada tikus Sprague Dawley

Program Studi Ilmu Gizi, Fakultas Ilmu – ilmu Kesehatan, Universitas Jenderal Soedirman, Indonesia

Received: 31 Jul 2018; Published: 30 Dec 2018.

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Abstract

Background: Biskuit are the most popular snack. Agustia et al (2016) have found biscuit made from mocaf-arrowroot substituted chicken’s liver and red spinach that has hight level of iron.

Objectives: The aim of this research was to determine the bioassay value of this biscuit.

Methods: The experiment was a trial of anemia recovery by providing 32 wistar rats with no iron-containing feeding for 7 days then continued for 14 days were given into 4 treatment groups, ½ serving biscuit (0.2 gram), 1 serving (0.8 gram) and 2 servings (0.4 grams) Statistical analysis was performed by using ANOVA dan LSD.

Results: The result showed that there are differences between groups  (p:0.00) and we found that the highest increase of Blood Fe and haemoglobin was in the group with 2 servings of biskuist (6.65 ± 0.49 µg/dl ; 3.62 ± 0.06 gr/dl).

Conclusion: Biscuit made from mocaf-arrowroot substituted liver and spinach can increase Blood Fe and haemoglobin in anemia rat.
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Keywords: anemia; biscuits; haemoglobin; iron; rats

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Language : EN
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  1. Gropper SS, Smith JL, Groff JL. Advanced nutrition and human metabolism 5th ed. Canada: Wadsworth, Cengange Learning; 2009
  2. Agustia FC, Subardjo YP, Sari HP. Pengembangan biskuit MOCAF-Garut dengan substitusi hati sebagai alternatif biskuit tinggi zat besi untuk balita. Jurnal Gizi dan Pangan. 2017;12(2):129-138
  3. Subagjo A, Witono Y, Fahmi F. 2008. Prosedur Operasi Standar (POS) Produksi Mocaf Berbasis Kluster. Trenggalek: Kementerian Negara Riset dan Teknologi:1-5
  4. Aini N, Wirawani N. 2013. Kontribusi MP-Asi biskuit substitusi tepung garut, kedelai, dan ubi jalar kuning terhadap kecukupan protein, vitamin A, kalsium, dan Zink pada bayi. Journal of Nutrition College. 2(4):458-466
  5. Simbolon DOS, Masfria, Sudarmi. 2012. Pemeriksaan kadar Fe dalam hati ayam ras dan ayam buras secara spektrofotometri serapan atom. J Nat Prod Pharma Chemi. 1(1):8-13
  6. Huma N, Rehman SU, Anjum FM, Murtaza MA. 2007. Food fortifcation strategy: preventing iron defciency anemia : A review. Crit Rev Food Sci Nutr. 47(3):259-265
  7. Wijaya C. Hubungan asupan zat gizi dengan kejadian anemia pada anak usia 6-23 bulan di Kabupaten Aceh Besar tahun 2011. Skripsi, Universitas Indonesia; 2012. unpublished
  8. Susilo J, Hamam H. Hubungan asupan zat besi dan inhibitornya sebagai prediktor kadar hemoglobin ibu hamil di Kabupaten Bantul Propinsi DIY, Berita Kedokteran Masyarakat 18 (1) : 1-8. 2009
  9. Mahmoed.I. Ibrahium and A.I. Hegazy. Iron Bioavailability of Wheat Biscuit Supplemented by Fenugreek Seed Flour. World Journal of Agricultural Sciences 5 (6): 769-776, ISSN 1817-3047. 2009
  10. Widjindyah A, Anwar S, Susetyowati SH. Pemanfaatan tepung daun kelor (Moringa oleifera Lamk) dengan pretreatment asam dan tepung ikan lele terhadap pemulihan anemia secara in vivo. Jurnal Gizi Klinik Indonesia IX(2); 2012
  11. Persatuan Ahli Gizi Indonesia (Persagi). Tabel Komposisi Pangan Indonesia. Jakarta: PT. Elex Media Komputindo, Kompas Gramedia; 2009
  12. Pandey S, Ganeshpurkar A, Bansal D, Dubey N. Hematopoietic Effect of Amaranthus cruentus Extract on Phenylhydrazine-Induced Toxicity in Rats. J Diet Suppl. 2016 Nov;13(6):607-15. doi: 10.3109/19390211.2016.1155685.2016
  13. Carter RC, Jacobson JL, Burden MJ, Armony-Sivan R, Dodge NC, Angelilli ML, Lozoff B, Jacobson SW. Iron deficiency anemia and cognitive function in infancy. Pediatrics. Volume 126, Number 2; 2010
  14. Schneider JM, Fujii ML, Lamp CL, Lonnerdal B, Dewey KG, Zidenberg-Cherr S. Anemia, iron deficiency, and iron deficiency anemia in 12–36-mo-old children from low-income families. Am J Clin Nutr. 82:1269-75; 2005
  15. Milman, N. Anemia-Still a major health problem in many parts of the world. Ann Hematol. 90: 369-377; 2011

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