DOI: https://doi.org/10.14710/jkli.65719

Polusi Udara dan Dermatitis Atopik: Suatu Tinjauan Literatur

1School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jl. Pluit Raya No. 2, Jakarta 14440, Indonesia

2Department of Dermatology and Venereology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jl. Pluit Raya No. 2, Jakarta 14440, Indonesia

Open Access Copyright 2025 Jurnal Kesehatan Lingkungan Indonesia under http://creativecommons.org/licenses/by-sa/4.0.

Citation Format:
Abstract

Latar belakang: Polusi udara di Indonesia saat ini cukup tinggi seiring dengan meningkatnya urbanisasi dan industrialisasi. Paparan polusi udara dapat merusak fungsi perlindungan kulit dan diduga berhubungan dengan dermatitis atopik. Studi ini bertujuan untuk mengulas perkembangan studi pengaruh polusi udara terhadap dermatitis atopik.

Metode: Studi ini merupakan tinjauan literatur dengan menggunakan basis data Pubmed, ClinicalKey, EBSCO, dan ProQuest yang terbit dalam 5 tahun terakhir dan berbahasa Inggris. Kata kunci yang digunakan adalah “particulate matter AND atopic dermatitis”.

Hasil: Hasil studi menunjukkan bahwa polusi udara dapat merusak sawar kulit dan memicu respon peradangan, sehingga memicu dermatitis atopik. Paparan polusi udara pada masa prenatal dan usia dini berhubungan dengan peningkatan insidensi dermatitis atopik pada anak-anak. Paparan jangka pendek terhadap kadar polutan tinggi dapat meningkatkan risiko kekambuhan dermatitis atopik. Prevalensi dermatitis atopik juga terus mengalami peningkatan di negara-negara berkembang.

Simpulan: Studi ini menyimpulkan bahwa polusi udara dapat menjadi pemicu ataupun memperparah gejala dermatitis atopik.

 

ABSTRACT

Title: Air pollution and atopic dermatitis: A literature review

Background: Currently, air pollution in Indonesia is quite high along with increasing urbanization and industrialization. Exposure to air pollution may cause damage to skin protective function and may be related to atopic dermatitis. This paper aims to review the progress of studies concerning the relationship between air pollution and atopic dermatitis.

Method: Studies, which were published in English within the last 5 years, were obtained through databases (Pubmed, ClinicalKey, EBSCO, and ProQuest). The keywords used are“particulate matter AND atopic dermatitis”

Result: Results show that air pollution may damage skin barrier and trigger inflammatory response, thereby inducing atopic dermatitis. Prenatal and early childhood exposure to air pollution were associated with increasing incidence of atopic dermatitis in children. Acute exposure to high pollutant causes the increase of atopic dermatitis relapse. The prevalence of atopic dermatitis is also increasing in developing countries.

Conclusion: This study concluded that air pollution may trigger or worsen the symptoms of atopic dermatitis.

 

Note: This article has supplementary file(s).

Fulltext View|Download |  CTA
Copyrigh Transfer Agreement
Subject
Type CTA
  Download (559KB)    Indexing metadata
 ES
Etichal Statement
Subject
Type ES
  Download (682KB)    Indexing metadata
 Turnitin
Turnitin
Subject
Type Turnitin
  Download (3MB)    Indexing metadata
Keywords: polusi udara; particulate matter; dermatitis atopik; urbanisasi; industrialisasi

Article Metrics:

Article Info
Section: Literature Review
Language : ID
Recent articles
Dampak Kualitas Udara Dalam Ruangan Terhadap Kejadian ISPA di Kecamatan Medan Denai, Kota Medan Evaluating Environmental and Public Health Risks of Medical Waste Incineration Using Air Dispersion Modeling in Indonesia Analisis Karakteristik Sampah Puntung Rokok dan Penilaian Indeks Cigarette Butt Pollution Index (CBPI) Di Pesisir Kabupaten Malang Selatan, Jawa Timur Polusi Udara dan Dermatitis Atopik: Suatu Tinjauan Literatur More recent articles
Most cited articles
Faktor Risiko Lingkungandan Kebiasaan Penduduk Berhubungan Dengan Kejadian Filariasis di Distrik Windesi Kabupaten Kepulauan Yapen Provinsi Papua Halaman Belakang Halaman Belakang Hubungan Paparan Pestisida Pada Masa Kehamilan Dengan Kejadian Berat Badan Bayi Lahir Rendah (BBLR) di Kecamatan Ngablak Kabupaten Magelang Halaman Belakang More cited articles
  1. WHO. Air pollution [Internet]. [cited 2023 Dec 6]. Available from: https://www.who.int/health-topics/air-pollution#tab=tab_1
  2. CDC. Particle pollution [Internet]. [cited 2023 Dec 6]. Available from: https://www.cdc.gov/air/particulate_matter.html
  3. WHO. Ambient (outdoor) air pollution [Internet]. [cited 2023 Dec 6]. Available from: https://www.who.int/news-room/fact-sheets/detail/ambient-(outdoor)-air-quality-and-health
  4. Susanto A. Air pollution and human health. Medical Journal of Indonesia. 2020;29(1):8–10. https://doi.org/10.13181/mji.com.204572
  5. Manisalidis I, Stavropoulou E, Stavropoulos A, Bezirtzoglou E. Environmental and Health Impacts of Air Pollution: A Review. Front Public Health. 2020;8(14):1–13. https://doi.org/10.3389/fpubh.2020.00014
  6. Greenstone M, Fan Q. Indonesia’s worsening air quality and its impact on life expectancy [Internet]. AQLI. 2019. Available from: https://aqli.epic.uchicago.edu/wp-content/uploads/2019/03/Indonesia-Report.pdf
  7. IQAir. 2022 World Air Quality Report
  8. Fadadu RP, Abuabara K, Balmes JR, Hanifin JM, Wei ML. Air pollution and atopic dermatitis, from molecular mechanisms to population-level evidence: A review. Int J Environ Res Public Health. 2023;20(3):2526. https://doi.org/10.3390/ijerph20032526
  9. Ahn K. The role of air pollutants in atopic dermatitis. Journal of Allergy and Clinical Immunology. 2014;134(5):993–9. https://doi.org/10.1016/j.jaci.2014.09.023
  10. Lai A, Owens K, Patel S, Nicholas M. The impact of air pollution on atopic dermatitis. Curr Allergy Asthma Rep. 2023;23(8):435–42. https://doi.org/10.1007/s11882-023-01095-w
  11. Park TH, Park S, Cho MK, Kim S. Associations of particulate matter with atopic dermatitis and chronic inflammatory skin diseases in South Korea. Clin Exp Dermatol. 2022;47(2):325–34. https://doi.org/10.1111/ced.14910
  12. Isaifan D, Crovella S, Soubra L, Al-Nesf M, Steinhoff M. Fc epsilon RI–neuroimmune interplay in pruritus triggered by particulate matter in atopic dermatitis patients. Int J Mol Sci. 2023;24:11851. https://doi.org/10.3390/ijms241411851
  13. Kim YM, Kim J, Ha SC, Ahn K. Effects of exposure to indoor fine particulate matter on atopic dermatitis in children. Int J Environ Res Public Health. 2021;18(21):11509. https://doi.org/10.3390/ijerph182111509
  14. Park SK, Kim JS, Seo HM. Exposure to air pollution and incidence of atopic dermatitis in the general population: A national population-based retrospective cohort study. J Am Acad Dermatol. 2022;87(6):1321–7. https://doi.org/10.1016/j.jaad.2021.05.061
  15. Narla S, Silverberg JI. The role of environmental exposures in atopic dermatitis. Curr Allergy Asthma Rep. 2020;20(12):74. https://doi.org/10.1007/s11882-020-00971-z
  16. Luger T, Amagai M, Dreno B, Dagnelie MA, Liao W, Kabashima K, et al. Atopic dermatitis: role of the skin barrier, environment, microbiome, and therapeutic agents. J Dermatol Sci. 2021;102(3):142–57. https://doi.org/10.1016/j.jdermsci.2021.04.007
  17. Bonamonte D, Filoni A, Vestita M, Romita P, Foti C, Angelini G. The role of the environmental risk factors in the pathogenesis and clinical outcome of atopic dermatitis. Biomed Res Int. 2019;2019:1–11. https://doi.org/10.1155/2019/2450605
  18. Ye C, Gu H, Li M, Chen R, Xiao X, Zou Y. Air pollution and weather conditions are associated with daily outpatient visits of atopic dermatitis in Shanghai, China. Dermatology. 2022;238(5):939–49. https://doi.org/10.1159/000522491
  19. Wang H, Li XB, Chu XJ, Cao NW, Wu H, Huang RG, et al. Ambient air pollutants increase the risk of immunoglobulin E–mediated allergic diseases: A systematic review and meta-analysis. Environ Sci Pollut Res Int. 2022;29(33):49534–52. https://doi.org/10.1007/s11356-022-20447-z
  20. Kim B, Kim J, Goleva E, Berdyshev E, Lee J, Vang KA, et al. Particulate matter causes skin barrier dysfunction. JCI Insight. 2021;6(5):e145185. https://doi.org/10.1172/jci.insight.145185
  21. Hsiao YY, Chen YH, Hung WT, Tang KT. The relationship between outdoor air pollutants and atopic dermatitis of adults: A systematic review and meta-analysis. Asian Pac J Allergy Immunol. 2022;40(4):295–307. https://doi.org/10.12932/AP-060922-1448
  22. Bellinato F, Adami G, Furci A, Cattani G, Schena D, Girolomoni G, et al. Association between short-term exposure to environmental air pollution and atopic dermatitis flare in patients treated with dupilumab. J Am Acad Dermatol. 2023;11:72–7. https://doi.org/10.1016/j.jdin.2023.01.018
  23. Trinh P, Allerup JAC, Li S, Ko J, Chen J, Linos E, et al. Association between yearlong air pollution and moderate-severe atopic dermatitis: A United States cross-sectional claims analysis. J Am Acad Dermatol. 2023;13:4–6. https://doi.org/10.1016/j.jdin.2023.04.017
  24. Noh SR, Kim JS, Kim EH, Jeon BH, Kim JH, Kim YM, et al. Spectrum of susceptibility to air quality and weather in individual children with atopic dermatitis. Pediatr Allergy Immunol. 2019;30(2):179–87. https://doi.org/10.1111/pai.13005
  25. Patella V, Florio G, Palmieri M, Bousquet J, Tonacci A, Giuliano A, et al. Atopic dermatitis severity during exposure to air pollutants and weather changes with an Artificial Neural Network (ANN) analysis. Pediatric Allergy and Immunology. 2020;31(8):938–45. https://doi.org/10.1111/pai.13314

Last update:

No citation recorded.

Last update: 2025-09-02 03:06:01

No citation recorded.