BibTex Citation Data :
@article{NMJN58052, author = {Tahiruddin Tahiruddin and Diah Indriastuti and Syahrul Syahrul and Andi Irwan and Satriya Pranata}, title = {A Pilot Study on Diabetes Distress, Insulin Growth Factor-I, Insulin-Like Growth Factor Binding Protein-3, and HbA1c in Diabetic Patients}, journal = {Nurse Media Journal of Nursing}, volume = {15}, number = {1}, year = {2025}, keywords = {Diabetes; HbA1c; IGF-I; IGFBP-3}, abstract = { Background: Diabetes distress refers to the emotional and psychological burden experienced by individuals in managing their condition, which can influence physiological outcomes and overall well-being. However, the relationship between HbA1c, insulin growth factor-I (IGF-I), and insulin-like growth factor binding protein-3 (IGFBP-3) with diabetes distress in diabetic patients remains elusive. Purpose: The objective of this study was to evaluate the association of IGF-I, IGFBP-3, and HbA1c with diabetes distress in diabetic patients. Methods: A cross-sectional design with purposive sampling was used to recruit subjects from the public health center in Kendari City, Southeast Sulawesi, Indonesia, from May to November 2021. A total of 30 diabetic patients were recruited. Distress data were collected using the Indonesian version of the Diabetes Distress Scale (DDS) questionnaire. HbA1c levels were measured using High-Performance Liquid Chromatography (HPLC). Serum levels of IGF-I and IGFBP-3 were measured using the ELISA (Enzyme-Linked Immunosorbent Assay) kit method. The data were analyzed using regression analysis. Results: Most respondents had moderate distress, with a DDS score of 53.4%, high IGF-I levels in 76.7%, and low IGFBP-3 levels in 76.7%. As many as 60% of respondents had an HbA1c level above 6.4%. IGF-I (ρ-value = 0.024) and IGFBP-3 levels (ρ-value = 0.042) were significantly correlated with diabetes distress. However, HbA1c levels were not significantly correlated with diabetes distress (ρ-value = 0.155). Conclusion: IGF-I and IGFBP-3 levels were associated with diabetes distress, but HbA1c was not. Patients with higher distress were found to have elevated serum levels of IGF-I and IGFBP-3. Future research should focus on stress management strategies that support efforts to prevent disease and complications associated with diabetes mellitus. }, issn = {2406-8799}, doi = {10.14710/nmjn.v15i1.58052}, url = {https://ejournal.undip.ac.id/index.php/medianers/article/view/58052} }
Refworks Citation Data :
Background: Diabetes distress refers to the emotional and psychological burden experienced by individuals in managing their condition, which can influence physiological outcomes and overall well-being. However, the relationship between HbA1c, insulin growth factor-I (IGF-I), and insulin-like growth factor binding protein-3 (IGFBP-3) with diabetes distress in diabetic patients remains elusive.
Purpose: The objective of this study was to evaluate the association of IGF-I, IGFBP-3, and HbA1c with diabetes distress in diabetic patients.
Methods: A cross-sectional design with purposive sampling was used to recruit subjects from the public health center in Kendari City, Southeast Sulawesi, Indonesia, from May to November 2021. A total of 30 diabetic patients were recruited. Distress data were collected using the Indonesian version of the Diabetes Distress Scale (DDS) questionnaire. HbA1c levels were measured using High-Performance Liquid Chromatography (HPLC). Serum levels of IGF-I and IGFBP-3 were measured using the ELISA (Enzyme-Linked Immunosorbent Assay) kit method. The data were analyzed using regression analysis.
Results: Most respondents had moderate distress, with a DDS score of 53.4%, high IGF-I levels in 76.7%, and low IGFBP-3 levels in 76.7%. As many as 60% of respondents had an HbA1c level above 6.4%. IGF-I (ρ-value = 0.024) and IGFBP-3 levels (ρ-value = 0.042) were significantly correlated with diabetes distress. However, HbA1c levels were not significantly correlated with diabetes distress (ρ-value = 0.155).
Conclusion: IGF-I and IGFBP-3 levels were associated with diabetes distress, but HbA1c was not. Patients with higher distress were found to have elevated serum levels of IGF-I and IGFBP-3. Future research should focus on stress management strategies that support efforts to prevent disease and complications associated with diabetes mellitus.
Article Metrics:
Last update:
Last update: 2025-05-03 10:01:11
In order for the Department of Nursing, Faculty of Medicine, Universitas Diponegoro to publish and disseminate research articles, we need non-exclusive publishing rights (transferred from the author(s) to the publisher). This is determined by a publishing agreement between the author(s) and the Department of Nursing, Faculty of Medicine, Universitas Diponegoro. This agreement involves the transfer or licensing of the copyright for publishing to the publisher, while authors still retain significant rights to use and share their own published articles. The Department of Nursing, Faculty of Medicine, Universitas Diponegoro supports the need for authors to share, disseminate, and maximize the impact of their research through these rights in any databases.
As the author(s), you have rights to a wide range of uses of your article, including use by your employing institution or company. These author rights can be exercised without the need to obtain specific permission. Authors publishing in the Nurse Media Journal of Nursing have extensive rights to use their works for teaching and scholarly purposes without needing to seek permission, including:
Authors, readers, and third parties can copy and redistribute the material in any medium or format, as well as remix, transform, and build upon the material for any purpose, even commercially, but they must give appropriate credit (including the name of the creator and attribution parties, detailed information about the authors, a copyright notice, an open access license notice, a disclaimer notice, and a link to the material), provide a link to the license, and indicate if changes were made. The publisher will indicate any modification of the material (if any) and retain an indication of previous modifications using a CrossMark Policy and information about Erratum-Corrigendum notifications.
Authors, readers, and third parties can read, print, and download, redistribute or republish the article (e.g., display it in a repository), translate the article, download it for text and data mining purposes, reuse portions or extracts from the article in other works, sell or reuse it for commercial purposes, remix, transform, or build upon the material. They must distribute their contributions under the same license as the original Creative Commons Attribution-ShareAlike (CC BY-SA).
The Authors submitting a manuscript do so on the understanding that if accepted for publication, non-exclusive right for publishing (publishing right) of the article shall be assigned/transferred to Publisher of the Nurse Media Journal of Nursing (Department of Nursing, Faculty of Medicine, Universitas Diponegoro).
Upon acceptance of an article, authors will be asked to complete a 'Copyright Transfer Agreement for Publishing (CTAP)'. An e-mail will be sent to the Corresponding Author confirming receipt of the manuscript together with a 'Copyright Transfer Agreement for Publishing' form by online version of this agreement.
Nurse Media Journal of Nursing and Department of Nursing, Faculty of Medicine, Universitas Diponegoro, the Editors and the Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Nurse Media Journal of Nursing are sole and exclusive responsibility of their respective authors and advertisers.
Please note that even though we ask for a transfer of copyright for publishing (CTAP), our journal Author(s) retain (or are granted back) significant scholarly rights as mentioned before.
The Copyright Transfer Agreement for Publishing (CTAP) Form can be downloaded here: [Copyright Transfer Agreement for Publishing (CTAP) Form NMJN 2024]
The copyright form should be signed electronically and send to the Editorial Office in the form of original e-mail below:
Dr. Meira Erawati (Editor-in-Chief)Editorial Office of Nurse Media Journal of Nursing Department of Nursing, Faculty of Medicine, Universitas Diponegoro Jl. Prof. Soedarto, Tembalang, Semarang, Central Java, Indonesia 50275Telp.: +62-24-76480919; Fax.: +62-24-76486849E-mail: media_ners@live.undip.ac.id
(This policy statements has been updated at 24th January 2024)
