BibTex Citation Data :
@article{NMJN70345, author = {Rika Sarfika and Endang Martini and Siti Yuliharni and I Made Moh. Yanuar Saifudin}, title = {Key Predictors of Medication Adherence Among Pulmonary Tuberculosis Patients: A Cross-Sectional Study in Palembang, Indonesia}, journal = {Nurse Media Journal of Nursing}, volume = {15}, number = {2}, year = {2025}, keywords = {Drug side effects; knowledge; medication adherence; support systems; tuberculosis}, abstract = { Background: Medication adherence remains a critical challenge in tuberculosis (TB) control, particularly in Indonesia, which ranks second globally in TB incidence. While previous studies have examined adherence factors worldwide, limited research has simultaneously evaluated the combined influence of sociodemographic, clinical, and psychosocial determinants in Indonesian settings, particularly using validated Indonesian-language instruments. Purpose: This study aimed to identify and quantify key predictors of medication adherence among pulmonary TB patients in Palembang, Indonesia, with particular emphasis on sociodemographic factors, clinical variables, and psychosocial determinants. Methods: A cross-sectional analytical study was conducted involving 150 pulmonary TB patients recruited through consecutive sampling at five public healthcare centers in Palembang. Data were collected using validated instruments, including the 8-item Morisky Medication Adherence Scale (MMAS-8) for adherence, the Knowledge About Tuberculosis Questionnaire (KATUB-Q) for TB knowledge, a structured questionnaire for side effects, the Treatment Motivation Questionnaire, the Multidimensional Scale of Perceived Social Support (MSPSS), and the TB-related Stigma Scale. Statistical analyses included descriptive statistics, Chi-square tests, and ordinal logistic regression to evaluate relationships between variables and adherence levels. Results: Only 20% of participants demonstrated high adherence, while 50.7% exhibited low adherence. Significant predictors of adherence included early adulthood (OR = 0.061, 95% CI = 0.004–0.857, p = 0.038) and middle adulthood (OR = 0.052, 95% CI = 0.005–0.565, p = 0.015), indicating lower adherence compared to late elderly. Other predictors were poor TB knowledge (OR = 0.316, 95% CI = 0.154–0.650, p = 0.002), low motivation (OR = 0.244, 95% CI = 0.108–0.553, p < 0.001), limited family support (OR = 0.470, 95% CI = 0.232–0.952, p = 0.036), insufficient healthcare worker support (OR = 0.349, 95% CI = 0.204–0.840, p = 0.015), and the presence of drug side effects (OR = 5.294, 95% CI = 2.134–13.126, p < 0.001). Younger adults showed lower adherence rates compared to older populations, while patients with better knowledge and stronger support systems demonstrated higher adherence. Conclusion: Key predictors of medication adherence were age, TB knowledge, motivation, family support, healthcare worker support, and drug side effects. Younger patients, those with poor knowledge, low motivation, weak support systems, and severe side effects demonstrated significantly lower adherence rates. These findings highlight the need for targeted, multifactorial interventions to improve TB treatment outcomes in Indonesia. }, issn = {2406-8799}, doi = {10.14710/nmjn.v15i2.70345}, url = {https://ejournal.undip.ac.id/index.php/medianers/article/view/70345} }
Refworks Citation Data :
Background: Medication adherence remains a critical challenge in tuberculosis (TB) control, particularly in Indonesia, which ranks second globally in TB incidence. While previous studies have examined adherence factors worldwide, limited research has simultaneously evaluated the combined influence of sociodemographic, clinical, and psychosocial determinants in Indonesian settings, particularly using validated Indonesian-language instruments.
Purpose: This study aimed to identify and quantify key predictors of medication adherence among pulmonary TB patients in Palembang, Indonesia, with particular emphasis on sociodemographic factors, clinical variables, and psychosocial determinants.
Methods: A cross-sectional analytical study was conducted involving 150 pulmonary TB patients recruited through consecutive sampling at five public healthcare centers in Palembang. Data were collected using validated instruments, including the 8-item Morisky Medication Adherence Scale (MMAS-8) for adherence, the Knowledge About Tuberculosis Questionnaire (KATUB-Q) for TB knowledge, a structured questionnaire for side effects, the Treatment Motivation Questionnaire, the Multidimensional Scale of Perceived Social Support (MSPSS), and the TB-related Stigma Scale. Statistical analyses included descriptive statistics, Chi-square tests, and ordinal logistic regression to evaluate relationships between variables and adherence levels.
Results: Only 20% of participants demonstrated high adherence, while 50.7% exhibited low adherence. Significant predictors of adherence included early adulthood (OR = 0.061, 95% CI = 0.004–0.857, p = 0.038) and middle adulthood (OR = 0.052, 95% CI = 0.005–0.565, p = 0.015), indicating lower adherence compared to late elderly. Other predictors were poor TB knowledge (OR = 0.316, 95% CI = 0.154–0.650, p = 0.002), low motivation (OR = 0.244, 95% CI = 0.108–0.553, p < 0.001), limited family support (OR = 0.470, 95% CI = 0.232–0.952, p = 0.036), insufficient healthcare worker support (OR = 0.349, 95% CI = 0.204–0.840, p = 0.015), and the presence of drug side effects (OR = 5.294, 95% CI = 2.134–13.126, p < 0.001). Younger adults showed lower adherence rates compared to older populations, while patients with better knowledge and stronger support systems demonstrated higher adherence.
Conclusion: Key predictors of medication adherence were age, TB knowledge, motivation, family support, healthcare worker support, and drug side effects. Younger patients, those with poor knowledge, low motivation, weak support systems, and severe side effects demonstrated significantly lower adherence rates. These findings highlight the need for targeted, multifactorial interventions to improve TB treatment outcomes in Indonesia.
Article Metrics:
Last update:
Last update: 2025-09-22 12:01:27
In order for the Department of Nursing, Faculty of Medicine, Universitas Diponegoro to publish and disseminate research articles, we need non-exclusive publishing rights (transferred from the author(s) to the publisher). This is determined by a publishing agreement between the author(s) and the Department of Nursing, Faculty of Medicine, Universitas Diponegoro. This agreement involves the transfer or licensing of the copyright for publishing to the publisher, while authors still retain significant rights to use and share their own published articles. The Department of Nursing, Faculty of Medicine, Universitas Diponegoro supports the need for authors to share, disseminate, and maximize the impact of their research through these rights in any databases.
As the author(s), you have rights to a wide range of uses of your article, including use by your employing institution or company. These author rights can be exercised without the need to obtain specific permission. Authors publishing in the Nurse Media Journal of Nursing have extensive rights to use their works for teaching and scholarly purposes without needing to seek permission, including (but not limited to):
Authors, readers, and third parties can copy and redistribute the material in any medium or format, as well as remix, transform, and build upon the material for any purpose, even commercially, but they must give appropriate credit (including the name of the creator and attribution parties, detailed information about the authors, a copyright notice, an open access license notice, a disclaimer notice, and a link to the material), provide a link to the license, and indicate if changes were made. The publisher will indicate any modification of the material (if any) and retain an indication of previous modifications using a CrossMark Policy and information about Erratum-Corrigendum notifications.
Authors, readers, and third parties can read, print, and download, redistribute or republish the article (e.g., display it in a repository), translate the article, download it for text and data mining purposes, reuse portions or extracts from the article in other works, sell or reuse it for commercial purposes, remix, transform, or build upon the material. They must distribute their contributions under the same license as the original Creative Commons Attribution-ShareAlike (CC BY-SA).
The Authors submitting a manuscript do so on the understanding that if accepted for publication, non-exclusive right for publishing (publishing right) of the article shall be assigned/transferred to Publisher of the Nurse Media Journal of Nursing (Department of Nursing, Faculty of Medicine, Universitas Diponegoro).
Upon acceptance of an article, authors will be asked to complete a 'Copyright Transfer Agreement for Publishing (CTAP)'. An e-mail will be sent to the Corresponding Author confirming receipt of the manuscript together with a 'Copyright Transfer Agreement for Publishing' form by online version of this agreement.
Nurse Media Journal of Nursing and Department of Nursing, Faculty of Medicine, Universitas Diponegoro, the Editors and the Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Nurse Media Journal of Nursing are sole and exclusive responsibility of their respective authors and advertisers.
Please note that even though we ask for a transfer of copyright for publishing (CTAP), our journal Author(s) retain (or are granted back) significant scholarly rights as mentioned before.
The Copyright Transfer Agreement for Publishing (CTAP) Form can be downloaded here: [Copyright Transfer Agreement for Publishing (CTAP) Form NMJN 2024]
The copyright form should be signed electronically and send to the Editorial Office in the form of original e-mail below:
Dr. Sri Padma Sari (Editor-in-Chief)Editorial Office of Nurse Media Journal of Nursing Department of Nursing, Faculty of Medicine, Universitas Diponegoro Jl. Prof. Soedarto, Tembalang, Semarang, Central Java, Indonesia 50275Telp.: +62-24-76480919; Fax.: +62-24-76486849E-mail: media_ners@live.undip.ac.id
(This policy statements has been updated at 24th January 2024)
