1Faculty of Medicine, Universitas Sumatera Utara/Adam Malik Hospital, Medan, Indonesia
2Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
BibTex Citation Data :
@article{JAI83520, author = {Cindy Linkoln and Andriamuri Lubis and Tasrif Hamdi}, title = {Correlation Between Electroencephalography-Based Sedation Indices (BIS and qCON) and Mean Arterial Pressure (MAP) in Sedated Postoperative Patients in the Intensive Care Unit}, journal = {JAI (Jurnal Anestesiologi Indonesia)}, volume = {0}, number = {0}, year = {2021}, keywords = {BIS; ICU; mean arterial pressure; postoperative; qCON; sedation}, abstract = { : To evaluate the correlation between BIS and qCON with MAP in sedated postoperative patients upon ICU admission. Methods: This analytical observational study with a cross-sectional design included 38 postoperative patients admitted to the ICU. All patients received a standardized sedative-analgesic regimen of midazolam and fentanyl. Sedation depth was assessed using BIS and qCON obtained from the CONOX ® monitor sequentially, while MAP was measured 10 minutes after sedation was administered. Data were analyzed using Spearman’s correlation test, with a p-value < 0.05 considered statistically significant. Results: The median BIS and qCON values were 61 (59–71) and 60 (59–70), respectively, indicating moderate sedation. The mean MAP was 90.9 ± 10.2 mmHg. BIS showed a moderate positive correlation with MAP (ρ = 0.481, p = 0.017), with an R² of 0.231, while qCON also demonstrated a moderate positive correlation with MAP (ρ = 0.433, p = 0.022), with an R² of 0.187. These findings indicate that higher sedation index values, reflecting lighter sedation, were associated with higher MAP. Conclusion: BIS and qCON are moderately correlated with MAP in sedated postoperative ICU patients, indicating an association between sedation depth and sympathetic activity. However, the modest strength of this relationship suggests that MAP is influenced by multiple factors beyond sedation depth. }, issn = {2089-970X}, doi = {10.14710/jai.v0i0.83520}, url = {https://ejournal.undip.ac.id/index.php/janesti/article/view/83520} }
Refworks Citation Data :
: To evaluate the correlation between BIS and qCON with MAP in sedated postoperative patients upon ICU admission.
Methods: This analytical observational study with a cross-sectional design included 38 postoperative patients admitted to the ICU. All patients received a standardized sedative-analgesic regimen of midazolam and fentanyl. Sedation depth was assessed using BIS and qCON obtained from the CONOX® monitor sequentially, while MAP was measured 10 minutes after sedation was administered. Data were analyzed using Spearman’s correlation test, with a p-value < 0.05 considered statistically significant.
Results: The median BIS and qCON values were 61 (59–71) and 60 (59–70), respectively, indicating moderate sedation. The mean MAP was 90.9 ± 10.2 mmHg. BIS showed a moderate positive correlation with MAP (ρ = 0.481, p = 0.017), with an R² of 0.231, while qCON also demonstrated a moderate positive correlation with MAP (ρ = 0.433, p = 0.022), with an R² of 0.187. These findings indicate that higher sedation index values, reflecting lighter sedation, were associated with higher MAP.
Conclusion: BIS and qCON are moderately correlated with MAP in sedated postoperative ICU patients, indicating an association between sedation depth and sympathetic activity. However, the modest strength of this relationship suggests that MAP is influenced by multiple factors beyond sedation depth.
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