Asupan seng dan status seng yang rendah sebagai faktor risiko kejadian infeksi filariasis (studi kasus di kota pekalongan)


Article Metrics: (Click on the Metric tab below to see the detail)

Article Info
Submitted: 17-10-2016
Published: 08-12-2016
Section: Articles
Fulltext PDF Tell your colleagues Email the author
Background: Microfilariae infections in the human body does not always cause symptoms. filaria infected humans would induce a Th2 response by increasing the production of IL-4, IL-5, IL-13 and increased serum levels of IgE. Zinc deficiency is directly related to the regulation of immune response that is reduced due to decline in lymphopoesis as well as the effect on the immune response and the production of antibodies in people with normal nutritional status.Objective: This research is analytic survey with case control approach. Samples were selected with a total engineering sample of 42 people infected with filariasis of the samples taken by Comparing the number of 1 : 1. The subjects of the study were obtained when only 30 cases and 30 controls chosen. Zinc intake assessment is done by using a food frequency ( FFQ ) and food recall 3 x 24 hours later treated with Nutrisoft program. Assessment of serum zinc performed with venous blood sampling as much as 3 cc made 1 time. Statistical analysis was performed with chi square test.Results: Group infected and not infected with filariasis less zinc intake was 54.7 % and 45.3 % , zinc status is lacking in both infected and uninfected group was 50.0 % and 50.0 %. Thus intake of zinc and zinc status were less does not constitute a risk factor in the study group ( zinc intake : Value- p = 0.103 ; OR = 7.250 with a value 95 % CI = 0.815 to 64.45 and zinc status : p - value = 1.000 ; OR = 1,000 with a value 95 % CI = 0.131 to 7.605 ).Conclusion: The intake of zinc and low zinc status is not a risk factor incidence of filariasis infection in areas of research.


filariasis; Asupan Seng; Seng Serum; Imunitas

  1. Dewi Nugraheni Restu Mastuti  Scholar
    Fakultas Kesehatan Masyarakat, Universitas Pekalongan, Indonesia