Sensitivitas dan spesifisitas lingkar pergelangan tangan sebagai prediktor obesitas dan resistensi insulin pada remaja akhir

Addina Rizky Fitriyanti  -  Prodi Ilmu Gizi, Fakultas Ilmu Keperawatan dan Kesehatan, Universitas Muhammadiyah Semarang, Indonesia
*Kusmiyati Tjahjono  -  Bagian Biokimia, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
Mohammad Sulchan  -  Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
Sunarto Sunarto  -  Jurusan Gizi, Politeknik Kesehatan Kemenkes Semarang, Indonesia
Received: 28 Sep 2018; Published: 14 Jun 2019.
Open Access
Citation Format:
Abstract

Background: Obesity is one of the risk factors for insulin resistance. Insulin resistance plays an important role in the pathogenesis of cardiovascular disease. Wrist circumference has the potential for predicting obesity and insulin resistance.

Objectives:. To evaluate the sensitivity and specificity of wrist circumference against obesity and insulin resistance in late adolescents.

Methods: The design of this study is a crossectional study with a sample of 85 students at Diponegoro University Semarang. Data collected consisted of anthropometric measurements (body weight, height, wrist circumference, neck circumference, waist circumference and pelvic girth) and blood vein sampling (fasting blood glucose and fasting insulin). Statistical analyses used in this study were Pearson or R Spearman correlation test.

Results: Wrist circumference was positively correlated with all biochemical parameters and anthropometric measurements except the waist hip ratio. Wrist circumference correlates positively and significantly with fasting insulin and HOMA-IR in male adolescents. The results of the ROC curve analysis showed that the AUC value of wrist circumference in male adolescents had better performance in predicting obesity (88% (95% CI, 76% - 100%)) than insulin resistance (81% (95% CI, 51% -100%)).

Conclusion: Wrist circumference is one of the anthropometric measurements that can be used for predicting obesity and insulin resistance in late adolescents.

Keywords: sensitivity; specivity; anthropometric measurement; wrist circumference; insulin resistance

Article Metrics:

Article Info
Section: Articles
Language: EN
In Vol 7, No 2 (2019)
Statistics: 840 1137
Related articles
Determinan kejadian stunting pada bayi usia 6 bulan di Kota Semarang Pengembangan pangan fungsional berbasis tepung okara dan tepung beras hitam (Oryza sativa L. indica) sebagai makanan selingan bagi remaja obesitas Lingkar lengan atas dan panjang ulna sebagai parameter antropometri untuk memperkirakan berat badan dan tinggi badan orang dewasa Perilaku gizi dan hidrasi selama kehamilan berhubungan dengan konstipasi Faktor agen, pejamu, dan lingkungan kejadian obesitas pada anak usia 5-6 tahun
  1. Shafiee G, Qorbani M, Heshmat R, Djalalinia S, Motlagh ME, Arefirad T, et al. Wrist circumference as a novel predictor of obesity in children and adolescents: The CASPIAN-IV study. J Pediatr Endocrinol Metab. 2018;31(7):717-725
  2. Hajsadeghi S, Firouzi A, Bahadoran P, Hassanzadeh M. The value of wrist circumference for predicting the presence of coronary artery disease and metabolic syndrome. Indian Heart J. 2016;68:S5–9
  3. Kelishadi R, Heidari-Beni M, Qorbani M, Motamed-Gorji N, Motlagh ME, Ziaodini H, et al. Association between neck and wrist circumferences and cardiometabolic risk in children and adolescents: The CASPIAN-V study. Nutrition. 2017;43–44:32–8
  4. Lysen LK, Donna A. Israel. Nutrition in Weight Management. In: Mahan LK, Raymond JL, editors. Krause’s Food and The Nutrition Care Process. 14th editi. Canada: Elsevier Inc. 2017. p. 383–402
  5. Amini A, Soltanian N, Iraj B, Askari G, Ebneyamin S, Ghias M, et al. Original article association of wrist circumference with cardio metabolic risk factors statistical analysis : J Pak Med Assoc. 2012;62(3 suppl 2):34–6
  6. Capizzi M, Leto G, Petrone A, Zampetti S, Papa RE, Osimani M, et al. Wrist circumference is a clinical marker of insulin resistance in overweight and obese children and adolescents. Circulation. 2011;123:1757–62
  7. Campagna G, Zampetti S, Gallozzi A, Giansanti S, Chiesa C, Pacifico L, et al. Excellent intra and inter-observer reproducibility of wrist circumference measurements in obese children and adolescents. PLoS One. 2016;11(6):1–10
  8. Ling JCY, Mohamed MNA, Jalaludin MY, Rampal S, Zaharan NL, Mohamed Z. Determinants of high fasting insulin and insulin resistance among overweight/obese adolescents. Sci Rep. 2016;6(October):1–10
  9. Mitrea A, Soare A, Popa SG, Tudor MN, Mota M, Pozzilli P. Wrist circumference: An independent predictor of both insulin resistance and chronic kidney disease in an elderly population. Rom J Diabetes, Nutr Metab Dis. 2013;20(3):323–9
  10. Watkins AN, Kelly AS, Prineas RJ, Marlatt KL, Dengel DR, Sinaiko AR, et al. Childhood wrist circumference is not a predictor of insulin resistance in adulthood. J Pediatr. 2015;166(4):1085–7
  11. Öztürk A, Çiçek B, Mazıcıoğlu MM, Zararsız G, Kurtoğlu S. Wrist circumference and frame size percentiles in 6-17-year-old Turkish children and adolescents in Kayseri. J Clin Res Pediatr Endocrinol. 2017;9(4):329–36
  12. Derakhshan A, Eslami A, Bozorgmanesh M, Sheikholeslami F, Azizi F, Hadaegh F. Wrist circumference as a novel negative risk factor for cardiovascular disease among adult men: a median follow-up of 9 years. J Endocrinol Invest. 2016;39(7):763–8
  13. Noudeh YJ, Hadaegh F, Vatankhah N, Momenan AA, Saadat N, Khalili D, et al. Wrist circumference as a novel predictor of diabetes and prediabetes: Results of cross-sectional and 8.8-year follow-up studies. J Clin Endocrinol Metab. 2013;98(2):777–84
  14. Obirikorang C, Obirikorang Y, Acheampong E, Anto EO, Toboh E, Asamoah EA, et al. Association of wrist circumference and waist-to-height ratio with cardiometabolic risk factors among type II diabetics in a Ghanaian population. J Diabetes Res. 2018;1–11
  15. Newbern D, Gumus Balikcioglu P, Balikcioglu M, Bain J, Muehlbauer M, Stevens R, et al. Sex Differences in biomarkers associated with insulin resistance in obese adolescents: metabolomic profiling and principal components analysis. J Clin Endocrinol Metab. 2014;99(12):4730–9
  16. Kautzky-Willer A, Harreiter J, Pacini G. Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus. Endocr Rev. 2016;37(3):278–316
  17. Garza FJG la, Ayala AEG, Nava MG, Monsivais LIM, Martinez AMS, Lopez ER, et al. Body frame size in school children is related to the amount of adipose tissue in different depots but not to adipose distribution. Am J Hum Biol. 2017;1–7
  18. Shao J, Wang Z, Yang T, Ying H, Zhang Y, Liu S. Bone regulates glucose metabolism as an endocrine organ through osteocalcin. Int J Endocrinol. 2015;1–9
  19. Namazi N, Djalalinia S, Mahdavi A, Hamid G, Morteza A. Association of wrist circumference with cardio-metabolic risk factors : a systematic review and meta-analysis. Eat Weight Disord - Stud Anorexia, Bulim Obes. 2018;1–11
  20. Mohebi R, Mohebi A, Sheikholeslami F, Azizi F, Hadaegh F. Wrist circumference as a novel predictor of hypertension and cardiovascular disease : results of a decade follow up in a West Asian cohort. J Am Soc Hypertens. 2014;8(11):800–7
  21. Dahlan MS. Analisis Penelitian Diagnostik. In: Penelitian Diagnostik. Jakarta: Salemba Medika; 2009. p. 20–30
  22. Tatar BT, Ersoy C, Kacan T, Kirhan E, Sarandol E. Neck and wrist circumferences propose a reliable approach to qualify obesity and insulin resistance. Med Sci. 2014;3(1):1013–25
  23. Khadilkar V, Chiplonkar S, Ekbote V, Kajale N, Mandlik R. Reference centile curves for wrist circumference for Indian children aged 3 – 18 years. J Pediatr Metab. 2018;91(20):1–6

Last update: 2021-03-02 15:10:31

No citation recorded.

Last update: 2021-03-02 15:10:31

No citation recorded.

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) and Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro as publisher of the journal.

Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc., will be allowed only with a written permission from Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition).

Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition), Faculty of Medicine, Universitas Diponegoro, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Indonesian Journal of Nutrition are sole and exclusive responsibility of their respective authors and advertisers.