Pengaruh pemberian susu almond terhadap glukosa darah puasa pada tikus diabetes

Ryta Ristantia Ningsih; Enny Probosari; Binar Panunggal

doi:10.14710/jgi.7.2.86-91

DOI: https://doi.org/10.14710/jgi.7.2.86-91

Pengaruh pemberian susu almond terhadap glukosa darah puasa pada tikus diabetes

Ryta Ristantia Ningsih, Enny Probosari, Binar Panunggal

Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

Received: 31 Oct 2018; Published: 14 Jun 2019.

BibTex Citation Data :

@article{JGI20857,
    author = {Ryta Ningsih and Enny Probosari and Binar Panunggal},
    title = {Pengaruh pemberian susu almond terhadap glukosa darah puasa pada tikus diabetes},
    journal = {Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition)},
  volume = {7},
    number = {2},
    year = {2019},
    keywords = {almond milk; fasting blood glucose; type 2 diabetes mellitus},
    abstract = {   Background:    Type 2   Diabetes Mellitus is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion and insulin action. Diet plus high fiber can help control glucose levels. Almond contains fiber, vitamin E, and magnesium that contributes to the fasting blood glucose levels. This study aimed to analyze the effect of almond milk to the fasting blood glucose diabetic rats.       Method:    This study used an experimental design with pre-post test control group design. The sample were Rattus norvegicus Wistar which were divided into 4 groups: K (-), K (+), A1 and A2. Almond milk was given in the group treatmeant for 14 days with a dose of 4.32 ml and 8.64 ml. Fasting blood glucose measurement taken before and after treatment used Oxidase Glucose - Peroxidase Aminoantypirin (GOD PAP). Analysis of data used paired t-test, ANOVA and Post Hoc.       Results:    The fasting blood glucose levels decreased significantly (p = 0.01) in the treatment group which were intervened with almond milk. A decrease in fasting blood glucose levels in a dose treatment group 1 for 116.96 ± 4.45 (p = 0:01), whereas in the group treated at a dose of 2 for 155.53 ± 3.15 (p = 0.01). There were a significant difference in decreased of the fasting blood glucose levels between the two treatment groups (p = 0.01).       Conclusion:     Giving a dose almond milk 4.32 ml and 8.64 ml for 14 days can lower the fasting blood glucose levels significantly.    },
   issn = {2338-3119},   pages = {86--91}  doi = {10.14710/jgi.7.2.86-91},
    url = {https://ejournal.undip.ac.id/index.php/jgi/article/view/20857}
}

Citation Format:

Abstract

Background: Type 2 Diabetes Mellitus is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion and insulin action. Diet plus high fiber can help control glucose levels. Almond contains fiber, vitamin E, and magnesium that contributes to the fasting blood glucose levels. This study aimed to analyze the effect of almond milk to the fasting blood glucose diabetic rats.

Method: This study used an experimental design with pre-post test control group design. The sample were Rattus norvegicus Wistar which were divided into 4 groups: K (-), K (+), A1 and A2. Almond milk was given in the group treatmeant for 14 days with a dose of 4.32 ml and 8.64 ml. Fasting blood glucose measurement taken before and after treatment used Oxidase Glucose - Peroxidase Aminoantypirin (GOD PAP). Analysis of data used paired t-test, ANOVA and Post Hoc.

Results: The fasting blood glucose levels decreased significantly (p = 0.01) in the treatment group which were intervened with almond milk. A decrease in fasting blood glucose levels in a dose treatment group 1 for 116.96 ± 4.45 (p = 0:01), whereas in the group treated at a dose of 2 for 155.53 ± 3.15 (p = 0.01). There were a significant difference in decreased of the fasting blood glucose levels between the two treatment groups (p = 0.01).

Conclusion: Giving a dose almond milk 4.32 ml and 8.64 ml for 14 days can lower the fasting blood glucose levels significantly.

Fulltext View|Download

Keywords: almond milk; fasting blood glucose; type 2 diabetes mellitus

Article Metrics:

Article Info

Section: Articles

Language : EN

In Vol 7, No 2 (2019)

Recent articles

Studi kualitatif faktor yang mempengaruhi orang tua dalam pemberian makan anak autis Status antioksidan dan oksidatif laki-laki yang mengalami kegemukan dengan pemberian minuman rosela ungu Kebiasaan konsumsi kopi teratur dan pengaruhnya terhadap resorpsi tulang: C-telopeptida dan kalsium serum pada olahragawan More recent articles

Most cited articles

Faktor risiko stunting pada anak umur 6-24 bulan di kecamatan Penanggalan kota Subulussalam provinsi Aceh Karakteristik makanan pendamping ASI balita yang disubstitusi dengan tepung ikan lele dan labu kuning Kadar seng dan kadar malondialdehyde pada penderita multi drug resistant tuberculosis dan tuberkulosis sensitif Pola makan dan indikator lemak tubuh pada remaja Front Matter More cited articles

PB PERKENI. Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia; 2015
Marcia N, Kathrin.P S, Karen L, Sara.L R. Diabetes Mellitus. In: Nutrition Therapy & Pathophysiology. 2nd Ed. 2010. p. 482–514
Silva EFF, Ferreira CMM, Pinho L de. Risk Factors And Complications In Type 2 Diabetes Outpatients. Rev. Assoc. Med. Bras. 2017;63(7):621–7
Veterinaria F De. Almond Milk Production and Study of Quality. Journal of Academia. 2012;2:1–8
Briviba K, Gräf V, Walz E, Guamis B, Butz P. Ultra high pressure homogenization of almond milk: Physico-chemical and physiological effects. Food Chem. 2016;192:82–9
Nelms M, P.Sucher K, Lacey K, Roth SL. Diabetes Mellitus. In: Nutrition Therapy & Pathophysiology. 2nd Ed. United States of America: Yolanda Cossio; 2010. p. 482–508
Annadurai T, Muralidharan AR, Joseph T, Hsu MJ, Thomas PA, Geraldine P. Antihyperglycemic And Antioxidant Effects Of A Flavanone , Naringenin , In Streptozotocin – Nicotinamide-Induced Experimental Diabetic Rats. Journal of Physiology and Biochemistry. 2012;307–18
Ghasemi A, Khalifi S, Jeddy S. Streptozotocin-Nicotinamide-Induced Rat Model Of Type 2 Diabetes. Acta Physiol Hung. 2014; 101(4):408-20
DiaSys Diagnostic Systems GmbH. Glucose GOD FS. 2006;
Antoun G, Nikpay M, Mcpherson R, Harper M. Is Type 2 Diabetes Associated with Impaired Capacity for Weight Loss ? Can J Diabetes. 2017; 42-3;
Gerald Litwack. Insulin and Sugars. Acad Press. 2018;
Li S-C, Liu Y-H, Liu J-F, Chang W-H, Chen C-M, Chen C-YO. Almond consumption improved glycemic control and lipid profiles in patients with type 2 diabetes mellitus. Metabolism. 2011;60(4):474–9
Akubude V, Egwuonwu C, Olaniyan A, Ekiti O, Ajala OE. Almond Processing in Nigeria : Problems and Prospects. 2017;183-177
Hern P, Camacho-barcia L. Nuts and Dried Fruits : An Update of Their Beneficial Effects on Type 2 Diabetes. Nutrient. 2017;1–34
Post RE, Iii AGM, King DE, Simpson KN. Dietary Fiber for the Treatment of Type 2 Diabetes Mellitus : A Meta-Analysis. The Journal of the American Board of Family Medicine. 2012;25(1)
Profile SEE. Beneficial Effects of High Dietary Fiber Intake in Patients with Type 2 Diabetes Mellitus. N Engl J Med 2000; 342:1392-1398
Garcia-bailo B, El-sohemy A, Haddad PS, Arora P, Benzaied F. Vitamins D , C , and E in the prevention of type 2 diabetes mellitus : modulation of inflammation and oxidative stress. Biologics. 2011;7–19
Rafraf M, Bazyun B, Sarabchian MA, Rafraf M, Bazyun B, Sarabchian MA, et al. Vitamin E Improves Serum Paraoxonase-1 Activity and Some Metabolic Factors in Patients with Type 2 Diabetes : No Effects on Nitrite / Nitrate Levels. J Am Coll Nutr. 2016;5724
Jr EW, Glass LC. Oxidative stress in type 2 diabetes : the role of fasting and postprandial glycaemia. Int J Clin Pract. 2006;60(3):308–314. doi: 10.1111/j.1368-5031.2006.00825.x
Simental-Mendía LE, Sahebkar A, Rodríguez-Morán M, Guerrero-Romero F. A systematic review and meta-analysis of randomized controlled trials on the effects of magnesium supplementation on insulin sensitivity and glucose control. Pharmacol Res. 2016;111:272–82
Gommers LMM, Hoenderop JGJ, Baaij JHF De. Hypomagnesemia in Type 2 Diabetes : A Vicious Circle ? Diabetes. 2016;65:3–13
Barbagallo M, Dominguez LJ. Magnesium and type 2 diabetes. World J Diabetes. 2015;6(10):1152–1157. doi: 10.4239/wjd.v6.i10.1152

Last update:

No citation recorded.

Last update: 2024-11-23 10:30:36

No citation recorded.

Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) is published under licensed of a CC BY-SA Creative Commons Attribution-ShareAlike 4.0 International License

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) and Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro as publisher of the journal.

Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc., will be allowed only with a written permission from Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition).

Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition), Faculty of Medicine, Universitas Diponegoro, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Indonesian Journal of Nutrition are sole and exclusive responsibility of their respective authors and advertisers.