DOI: https://doi.org/10.14710/jitaa.44.3.243-251

Exploring effects of betaine-homocysteine methyltransferase (BHMT) gene polymorphisms on fatty acid traits and cholesterol in sheep

J. P. Munyaneza  -  Graduate School of IPB University, IPB University, Indonesia
*A. Gunawan  -  Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Indonesia
R. R. Noor  -  Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Indonesia
Open Access Copyright (c) 2019 Journal of the Indonesian Tropical Animal Agriculture

Citation Format:
Abstract

This study was aimed to explore the effects of Betaine-Homocysteine Methyltransferase (BHMT) gene polymorphisms on fatty acid traits and cholesterol in lambs. This study used a total of 147 blood samples for genotyping including 19 Javanese Fat-Tailed (JFT), 16 Javanese Thin-Tailed (JTT), 41 Composite Garut (CG), 35 Compass Agrinak (CA) and 36 Barbados Black Belly Cross (BC). A total of 61 rams as representative from five breed of sheep were selected for association study. Identification of BHMT single nucleotide polymorphisms was analyzed by PCR-RFLP method. Association of BHMT genotypes with fatty acid traits and cholesterol was performed by T-TEST. BHMT genotyping resulted into three genotypes (CC, CT and TT). Gene frequency of BHMT (g. 9947372 C>T) was in Hardy-Weinberg Equilibrium, excluding Javanese Fat-Tailed sheep. Association of BHMT genotypes with fatty acid traits resulted into a significant association (P<0.05) with C14:1, C17:1 and C18:0 fatty acids but not with cholesterol in sheep. SNP g. 9947372 (C>T) of BHMT gene might be a useful marker for selecting and producing sheep meat with desirable fatty acids.

 

Fulltext View|Download
Keywords: BHMT; Fatty acid; Sheep; SNP

Article Metrics:

Article Info
Section: Articles
Language : EN
Recent articles
Production, quality and livestock carrying capacity of Panicum maximum and Sesbania grandiflora at saline soil with different manure application Effects of zeolite inclusion in aflatoxin B1-contaminated diet on the performance of laying duck Correlations between age of Bali bull and semen production at National Artificial Insemination Center, Singosari - Indonesia Front-matter (Sept 2019) Back-matter (Sept 2019) More recent articles
Most cited articles
COMPARATIVE STUDY ON ANGIOTENSIN CONVERTING ENZYME INHIBITORY ACTIVITY OF HYDROLYSATE OF MEAT PROTEIN OF INDONESIAN LOCAL LIVESTOCKS THE PROFILE OF VAGINAL TEMPERATURE AND CYTOLOGY OF VAGINAL SMEAR IN BALI CATTLE DURING ESTRUS CYCLE PHASE THE CHEMICAL COMPOSITION AND VARIOUS SAMPLES PREPARATION METHODS FOR In Vitro GAS TEST OF TWO TROPICAL FEEDS Predicting the age and weight at puberty of Ongole Grade cattle using nonlinear mathematical model in Kebumen Farmer Association Evaluation of some insects as potential feed ingredients for ruminants: chemical composition, in vitro rumen fermentation and methane emissions More cited articles

Last update:

  1. Association study and expression analysis of olfactomedin like 3 gene related to meat quality, carcass characteristics, retail meat cut, and fatty acid composition in sheep

    Kasita Listyarini, Cece Sumantri, Sri Rahayu, Muhammad Jasim Uddin, Asep Gunawan. Animal Bioscience, 35 (10), 2022. doi: 10.5713/ab.21.0406

  2. Characterization of the Hepatic Transcriptome for Divergent Immune-Responding Sheep Following Natural Exposure to Gastrointestinal Nematodes

    Olivia Willoughby, Niel A. Karrow, Samla Marques Freire Cunha, Victoria Asselstine, Bonnie A. Mallard, Ángela Cánovas. Genes, 15 (6), 2024. doi: 10.3390/genes15060713

  3. Identification and association of polymorphism in THOC5 gene with fatty acid composition in Indonesian sheep

    K Listyarini, C Sumantri, S Rahayu, M J Uddin, A Gunawan. IOP Conference Series: Earth and Environmental Science, 788 (1), 2021. doi: 10.1088/1755-1315/788/1/012020

  4. Association of single-nucleotide polymorphisms in dual specificity phosphatase 8 and insulin-like growth factor 2 genes with inosine-5′-monophosphate, inosine, and hypoxanthine contents in chickens

    Jean Pierre Munyaneza, Minjun Kim, Eunjin Cho, Aera Jang, Hyo Jun Choo, Jun Heon Lee. Animal Bioscience, 36 (9), 2023. doi: 10.5713/ab.23.0080

  5. Evaluation of Fatty Acid Composition in Korean Native Chicken Breast Meat

    Jean Pierre Munyaneza, Eunjin Cho, Minjun Kim, Aera Jang, Hyo Jun Choo, Jun Heon Lee. Korean Journal of Poultry Science, 51 (1), 2024. doi: 10.5536/KJPS.2024.51.1.21

Last update: 2024-09-20 12:12:20

No citation recorded.