The Degree of Diabetic Wounds Affects Kidney Function Damage

*Emyk Windartik  -  Department of Basic Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Ima Rahmawati  -  Department of Basic Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Ita Ainun Jariyah  -  Department of Basic Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Raras Merbawani  -  Department of Basic Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Indah Lestari  -  Department of Maternity Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Ifa Ro’ifah  -  Department of Basic Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Arief Andriyanto orcid  -  Department of Community Nursing, STIKes Bina Sehat PPNI Mojokerto, Indonesia
Received: 15 Jul 2019; Revised: 21 Oct 2019; Accepted: 27 Dec 2019; Published: 30 Dec 2019.
Open Access Copyright (c) 2019 Nurse Media Journal of Nursing


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Section: Articles
Language: EN
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Abstract

Background: The peripheral neuropathy is the cause of hospitalization for patients with diabetes mellitus (DM) and damages kidney function due to the circulatory system with high sugar levels. High sugar levels in DM patients with diabetic wounds can trigger glomerular damage resulting in the decrease of kidney function.

Purpose: This study aims to analyze the relationship between the degree of diabetic wounds and kidney functions in patients with DM.

Methods: A cross-sectional study was conducted on 723 DM patients who experienced diabetic wounds in a hospital in Mojokerto, East Java, Indonesia. A purposive sampling technique was used to recruit the samples. The data of this study were medical records of diabetic patients. A simple linear regression test was employed to analyze the data.

Results: The result showed that the degree of diabetic wound was significantly related to kidney function damage (p=0.000). The relationship between the degree of diabetic wounds and the decline in kidney function was shown by an R-squared value of 0.768, meaning that the degree of diabetic wound affected the decline of kidney function by 76.8%, while the 23.2% was affected by other factors.

Conclusion:The degree of diabetic injury affects the decline of kidney function in DM patients by 76.8%. Nurses should do health promotion about controlling blood sugar levels in DM patients with the prevention of four pillars of diabetes, including education, nutrition, physical activity, and stress.

 

Keywords: Diabetes mellitus; diabetic wounds; kidney function

Article Metrics:

  1. Abdulah, D. M., Hassan, A. B., Saadi, F. S., & Mohammed, A. H. (2018). Impacts of self-management education on glycaemic control in patients with type 2 diabetes mellitus. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 12(6), 969–975. https://doi.org/10.1016/j.dsx.2018.06.007
  2. Abu Al-Halaweh, A., Davidovitch, N., Almdal, T. P., Cowan, A., Khatib, S., Nasser-Eddin, L., & Baradia, Z. (2017). Prevalence of type 2 diabetes mellitus complications among palestinians with T2DM. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 11(2017), S783–S787. https://doi.org/10.1016/j.dsx.2017.05.017
  3. Ahdizadeh, M., Peymam, N., Taghipour, A., Esmaily, H., & Mahdizade, S. (2013). Effect of health education program on promoting physical activity among diabetic women in Mashhad, Iran: applying social cognitive theory. J Res Health Sci, 13(1):90–7. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/23772021
  4. Al-Hariri, M. T., Al-Enazi, A. S., Alshammari, D. M., Bahamdan, A. S., AL-Khtani, S. M., & Al-Abdulwahab, A. A. (2017). Descriptive study on the knowledge, attitudes and practices regarding the diabetic foot. Journal of Taibah University Medical Sciences, 12(6), 492–496. https://doi.org/10.1016/j.jtumed.2017.02.001
  5. Avogaro, A., & Fadini, G. P. (2019). Microvascular complications in diabetes: A growing concern for cardiologists. International Journal of Cardiology, (xxxx). https://doi.org/10.1016/j.ijcard.2019.02.030
  6. Baghianimoghadam, Hadavandkhani, Mohammadi, & Fallahzade. (2012). Current education versus peer-education on walking in type 2 diabetic patients based on Health Belief Model: a randomized control trial study, 50(2):165–72. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/23326961
  7. Carretero Gómez, J., & Arévalo Lorido, J. C. (2018). Clinical assessment and treatment of diabetes in patients with chronic kidney disease. Revista Clinica Espanola, 218(6), 305–315. https://doi.org/10.1016/j.rce.2018.03.016
  8. Chen, C. H., Lin, K. Der, Ke, L. Y., Liang, C. J., Kuo, W. C., Lee, M. Y., … Shin, S. J. (2019). O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes. Biochimica et Biophysica Acta - General Subjects, 1863(6), 1059–1069. https://doi.org/10.1016/j.bbagen.2019.03.014
  9. Chowdhury, A., Khan, H., Lasker, S. S., & Chowdhury, T. A. (2019). Fasting outcomes in people with diabetes and chronic kidney disease in east london during ramadan 2018: the east london diabetes in ramadan survey. Diabetes Research and Clinical Practice. https://doi.org/10.1016/j.diabres.2019.05.022
  10. Dwi, A., Amatayakul, A., & Karuncharernpanit, S. (2017). International Journal of Nursing Sciences Predictors of diabetes self-management among type 2 diabetics in Indonesia : Application theory of the health promotion model. International Journal of Nursing Sciences, 4(3), 260–265. https://doi.org/10.1016/j.ijnss.2017.06.010
  11. Ghandour, R., Mikki, N., Abu Rmeileh, N. M. E., Jerdén, L., Norberg, M., Eriksson, J. W., & Husseini, A. (2018). Complications of type 2 diabetes mellitus in Ramallah and al-Bireh: The Palestinian Diabetes Complications and Control Study (PDCCS). Primary Care Diabetes, 12(6), 547–557. https://doi.org/10.1016/j.pcd.2018.07.002
  12. Hughes-Carter, D. L., Liu, C. C., & Hoebeke, R. E. (2018). Improved Screening and Diagnosis of Chronic Kidney Disease in the Older Adult With Diabetes. Journal for Nurse Practitioners, 14(8), 626–632.e3. https://doi.org/10.1016/j.nurpra.2018.07.008
  13. Joiner, K. L., Nam, S., & Whittemore, R. (2017). Lifestyle interventions based on the diabetes prevention program delivered via eHealth : A systematic review and meta-analysis. Preventive Medicine, 100, 194–207. https://doi.org/10.1016/j.ypmed.2017.04.033
  14. Laddha, A. P., & Kulkarni, Y. A. (2019). Tannins and vascular complications of Diabetes: An update. Phytomedicine, 56(August 2018), 229–245. https://doi.org/10.1016/j.phymed.2018.10.026
  15. Lee, S. J., & Chung, C. W. (2014). Health behaviors and risk factors associated with chronic kidney disease in Korean patients with diabetes: The fourth Korean national health and nutritional examination survey. Asian Nursing Research, 8(1), 8–14. https://doi.org/10.1016/j.anr.2013.11.001
  16. Limkunakul, C., de Boer, I. H., Kestenbaum, B. R., Himmelfarb, J., Ikizler, T. A., & Robinson-Cohen, C. (2019). The association of glycated hemoglobin with mortality and ESKD among persons with diabetes and chronic kidney disease. Journal of Diabetes and Its Complications, 33(4), 296–301. https://doi.org/10.1016/j.jdiacomp.2018.12.010
  17. Nejhaddadgar, N., Darabi, F., Rohban, A., Solhi, M., & kheire, M. (2018). Effectiveness of self-management program for people with type 2 diabetes mellitus based on PRECEDE PROCEED model. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. https://doi.org/10.1016/j.dsx.2018.08.016
  18. Sari, & Hisyam. (2014). Hubungan Antara Diabetes mellitus tipe II dengan kejadian Gagal Ginjal kronik Di Rumah sakit PKU Muhammadiyah Yogyakarta Periode januari 2011- oktober 2012. Jkki, 6 No. 1(1), 11–18.
  19. Tuomilehto, J., Lindstr, J., & Eriksson, J. (2017). STANDARDS OF MEDICAL CARE IN DIABETES — 2017 Standards of Medical Care in Diabetes d 2017, 40(January).