DOI: https://doi.org/10.14710/jai.v0i0.58873

Enteral Nutrition Tolerability Assessment in Septic Shock Patients in The ICU of RSUP H. Adam Malik Medan

1Master of Clinical Medicine Study Program/Anesthesiology and Intensive Care Study Program, Faculty of Medicine, Universitas Sumatera Utara/RSUP H. Adam Malik, Medan, Indonesia

2Departement of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara/RSUP H. Adam Malik, Medan, Indonesia

Received: 13 Oct 2023; Revised: 13 Sep 2024; Accepted: 13 Sep 2024; Available online: 9 Oct 2024.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

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Abstract

Background: Enteral nutrition is recommended within 24 to 48 hours after intensive care unit (ICU) admission when resuscitation and hemodynamic stability have been achieved. This study aims to determine the tolerability of enteral nutrition in septic shock patients in the ICU. 

Objective: To determine the tolerability of enteral nutrition in septic shock patients in the ICU of RSUP H. Adam Malik Medan.

Methods: This study is a retrospective observational study, which was conducted in the ICU of the RSUP H. Adam Malik Medan by taking patient data from January to December 2022. The samples were septic shock patients who were admitted to the ICU using mechanical ventilation and vasopressors with a length of treatment of more than 48 hours. Data was collected on the time required for enteral nutrition administration, as well as assessing patient tolerability (presence of vomiting, residuals, and incidence of ileus). Other assessments included length of stay and mortality rate.

Result: This study consisted of 47 samples, with 23 male (48.9%) and 24 female (51.1%) samples. Based on the underlying disease, 40.4% of the samples were diagnosed with pneumonia. In the tolerability of enteral nutrition, 83% of the samples were tolerant of early enteral nutrition, but with a high mortality rate of 89.4%. The initiation time of enteral nutrition in patients was 4.94 ± 1.79 hours (p=0.001). The average hospital stay for sepsis patients was 7.30 ± 6.55 days (p=0.001).

Conclusion: Most sepsis and septic shock patients in the ICU are tolerant of early enteral nutrition <24 hours, but it does not reduce mortality.

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Keywords: anesthesia; enteral nutrition; ICU; sepsis; tolerability

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Section: Original Articles
Language : EN
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  8. Singer P, Blaser AR, Berger MM, Alhazzani W, Calder PC, Casaer MP, Hiesmayr M, Mayer K, Montejo JC, Pichard C, Preiser JC. ESPEN guideline on clinical nutrition in the intensive care unit. Clinical nutrition. 2019 Feb 1;38(1):48-79
  9. Tatsumi H. Enteral tolerance in critically ill patients. Journal of intensive care. 2019 Dec;7(1):1-0
  10. Merchan C, Altshuler D, Aberle C, Papadopoulos J, Schwartz D. Tolerability of enteral nutrition in mechanically ventilated patients with septic shock who require vasopressors. Journal of Intensive Care Medicine. 2017 Oct;32(9):540-6
  11. Irawati D, Suwarman IS. Waktu Inisiasi dan Pemenuhan Asupan Nutrisi Enteral pada Pasien yang Menggunakan Ventilasi Mekanik di Intensive Care Unit (ICU) Rumah Sakit Dr. Hasan Sadikin Bandung. 2020
  12. Peng L, Wu LG, Li B, et al. Early enteral nutrition improves intestinal immune barrier in a rat model of severe acute pancreatitis. J Hepatobiliary Pancreat Sci 2016;23:681-7. Peng L, Wu LG, Li B, et al. Early enteral nutrition improves intestinal immune barrier in a rat model of severe acute pancreatitis. J Hepatobiliary Pancreat Sci 2016;23:681-7
  13. Hatman FA, Semedi BP, Budiono B. Analisis Faktor Risiko terhadap Lama Perawatan Pasien Sepsis yang Meninggal di Ruang Perawatan Intensif RSUD Dr. Soetomo Surabaya. JAI (Jurnal Anestesiologi Indonesia). 2021;13(2):78-87
  14. Takegawa R, Kabata D, Shimizu K, Hisano A, Ogura H, et al. Serum albumin as a risk factor for death in patients with prolonged sepsis. An observational study. Journal of Critical Care. 2019;51:139-144
  15. Pasinato V, Berbigier M, Rubin B, Castro K, Moraes R, Perry ID. Enteral nutritional therapy in septic patients in the intensive care unit: compliance with nutritional guidelines for critically ill patients. Rev Bras Ter Intensive. 2013;25(1):17-24

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