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COMPARISON OF THE EFFECTIVENESS OF LOCAL ANESTHETIC INFILTRATION OF 0.25% ROPIVACAINE AND 0.375% ROPIVACAINE ON CESAREAN SECTION INCISION WITH SPINAL ANESTHESIA

1Resident in Medical Education Program, Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia, Indonesia

2Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia, Indonesia

3Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia

4 Department of Community Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia, Indonesia

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Received: 31 Oct 2024; Revised: 15 Jan 2026; Accepted: 26 Jan 2026; Available online: 26 Jan 2026.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

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Abstract

Background: Postoperative pain after a caesarean section impacts recovery and needs effective treatment. Ropivacaine is a local anesthetic used to manage this pain, but there is limited comparison between its 0.25% and 0.375% concentrations.

Objective: To compare the effectiveness of ropivacaine dosages as local anesthetic infiltrates agent of 0.25% versus 0.375% by concentrations on Cesarean section incision.

Methods: This randomized controlled trial included 60 patients who received caesarean section with spinal anesthesia at Adam Malik Hospital Medan, Haji Hospital Medan, Prof. Chairuddin P. Lubis USU Hospital Medan, dan Putri Hijau Hospital Medan. Patients were divided into three groups: ropivacaine 0.25% (n=20), ropivacaine 0.375% (n=20), and a control group (n=20). Pain was measured using the Numerical Rating Scale (NRS) at 2, 6, 12, and 24 hours after surgery. Additional analgesic use and side effects were also recorded. Data were analyzed with the Kruskal-Wallis test (p<0.05).

Results: Postoperative pain after a caesarean section impacts recovery and needs effective treatment. Ropivacaine is a local anesthetic used to manage this pain, but there is limited comparison between its 0.25% and 0.375% concentrations.

Conclusions: Both 0.25% and 0.375% ropivacaine effectively reduce postoperative pain and the need for additional analgesics compared to control group. However, there was no significant difference between two ropivacaine concentrations.

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Keywords: Cesarean section; Dosage concentration; Local anesthetic; Postoperative pain; Ropivacain

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