DOI: https://doi.org/10.14710/jai.v0i0.69005

Comparison Between the Use of 10% Lidocaine Spray on the Mole Palate, Posterior Pharynx, Tonsillar Pillar, Hypopharynx, and Endotracheal Tube on Hemodynamics and Post-Intubation Throat Pain

1Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia

2Health Care Department of Public Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia

Received: 11 Dec 2024; Revised: 5 Jun 2025; Accepted: 25 Aug 2025; Available online: 26 Aug 2025.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

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Abstract

Background: Intubation causes various side effects such as pain and parasympathetic stimulation, hemodynamic changes, increased intracranial pressure, and increased risk of intracranial hemorrhage. Topical lidocaine has been applied for decades via intratracheal spray, oxygen atomization, intracuff filling, or gel lubrication due to its simple operation advantages. Topical lidocaine is one of the drugs of choice to prevent post-intubation sore throat by decreasing the permeability of nerve membrane cells to sodium ions.

Objective: To determine the relationship between the use of 10% lidocaine spray on the mole palate, posterior pharynx, tonsillar pillar, hypopharynx, and endotracheal tube on hemodynamics and post-intubation throat pain.

Methods: The design of this study used a single-blind randomized clinical trial with 17 research subjects for each group. Group A was given xylocaine spray on the endotracheal tube, and 17 subjects belonging to group B were given xylocaine spray on the soft palate, hypopharynx, and tonsil pillars.

Result: Mean arterial pressure in this study in group A was found to be 91.11 + 6.55 and in group B 91.11 + 6.55, for post-operative sore throat (POST) scores in group A 0.51 + 0.26 and for group B 1.21 + 0.13.

Conclusion: There is a difference between the use of 10% lidocaine spray on the soft palate, posterior pharynx, tonsillar pillars, hypopharynx, and endotracheal tube on hemodynamics and the incidence of sore throat after endotracheal intubation in elective patients with general anesthesia at RS Adam Malik, Medan.

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Keywords: intubation; lidocaine spray; mean arterial pressure; post intubation; sore throat

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Section: Original Articles
Language : EN
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