DOI: https://doi.org/10.14710/jai.v0i0.82363

Efficacy of Ultrasound-Guided Bilateral Infraorbital Nerve Block Combined with General Anesthesia on Postoperative Pain and Quality of Recovery in Patients Undergoing Nasal Surgery: A Randomized Controlled Trial

Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Udayana/ RS Ngoerah Denpasar Indonesia, l. Diponegoro No. 45, Denpasar‎, Indonesia, Indonesia

Received: 10 Feb 2026; Revised: 16 Apr 2026; Accepted: 30 Apr 2026; Available online: 30 Apr 2026.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

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Abstract

Background: Postoperative pain following nasal surgery is frequently moderate to severe, often necessitating high doses of opioids which subsequently increase the risk of adverse clinical effects.

Objective: This study aimed to evaluate the clinical impact of integrating ultrasound-guided bilateral infraorbital nerve blocks with general anesthesia on the quality of analgesia and postoperative recovery in patients undergoing nasal procedures.

Methods: A single-blind randomized controlled trial was conducted involving 38 patients at Ngoerah Hospital between June and August 2025. Participants were randomly assigned to either Group P1 (general anesthesia with bilateral infraorbital block using 2 mL of 0.5% bupivacaine per side) or Group P2 (general anesthesia only). Measured outcomes included Numerical Rating Scale (NRS) scores at 12 and 24 hours, time to first Patient-Controlled Analgesia (PCA) demand, 24-hour total fentanyl consumption, and Quality of Recovery-15 (QoR-15) scores.

Results: Baseline characteristics were comparable between groups. Group P1 demonstrated significantly lower NRS scores at 12 hours and 24 hours (p<0.001) compared to Group P2. Furthermore, P1 required significantly less PCA intervention (31.6% vs 100%, p<0.001), exhibited a longer duration before the first analgesic demand (p=0.008), and consumed less total fentanyl over 24 hours (p<0.001). The QoR-15 scores were also significantly higher in Group P1 (p<0.001), indicating superior recovery quality.

Conclusion: Supplementing general anesthesia with bilateral infraorbital nerve blocks effectively mitigates postoperative pain, reduces opioid dependency, and enhances the overall quality of recovery after nasal surgery.

 

Keywords: analgesia; infraorbital nerve block; multimodal; nasal surgery; postoperative pain; QoR-15.

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Language : EN
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