Perbandingan Validitas Sistem Skoring Apache II, SOFA, Dan Customized Sequential Organ Failure Assessment (Csofa) Untuk Memperkirakan Mortalitas Pasien Non-Bedah Yang Dirawat Di Ruang Perawatan Intensif

*Stefanus Taofik -  Bagian/ SMF Ilmu Anestesi dan Terapi Intensif Fakultas Kedokteran, Universitas Udayana/ Rumah Sakit Umum Pusat Sanglah Denpasar, Indonesia
Tjokorda Agung Senapathi -  Bagian/ SMF Ilmu Anestesi dan Terapi Intensif Fakultas Kedokteran, Universitas Udayana/ Rumah Sakit Umum Pusat Sanglah Denpasar, Indonesia
I Made Wiryana -  Bagian/ SMF Ilmu Anestesi dan Terapi Intensif Fakultas Kedokteran, Universitas Udayana/ Rumah Sakit Umum Pusat Sanglah Denpasar, Indonesia
Published: 1 Jul 2015.
Open Access
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Article Info
Section: Penelitian
Language: ID
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In Vol 7, No 2 (2015): Jurnal Anestesiologi Indonesia
Statistics: 437 183
Abstract

Latar Belakang : Penerapan Sistem Jaminan Kesehatan Nasional (SJKN) dalam pelayanan ICU mendorong pelayanan ICU untuk lebih efektif dan efisien. Prediksi hasil perawatan penting baik secara administrasi ataupun klinis dalam manajemen ICU. Pasien non-bedah meskipun jumlahnya tidak banyak, namun memiliki angka mortalitas yang tinggi.

Tujuan : Untuk mendapatkan sistem skoring yang baik dan mudah diterapkan dilakukan penilaian missing value, dan diskriminasi dari masing masing sistem skoring.

Metode : Penelitian ini melibatkan 184 pasien non-bedah yang dirawat di ICU RSUP Sanglah Denpasar yang diambil secara retrospektif dari data tanggal 1 Januari 2014 sampai dengan 31 Desember 2014. Semua pasien dilakukan penilaian APACHE II, SOFA, dan CSOFA. Uji analisis regresi logistik dilakukan untuk menilai pengaruh masing masing sub variabel terhadap mortalitas, dan selanjutnya mencari cut off point dari analisis kurva ROC untuk mendapatkan sensitifitas dan spesifisitas masing masing.

Hasil : Area under Receiver Operating Characteristic (AuROC) pada APACHE II, SOFA, dan CSOFA berturut turut didapatkan 0,892, 0,919, dan 0,9172. Missing value terbanyak didapatkan berturut turut pada SOFA, APACHE II, dan CSOFA sebesar 84,23%, 8,15%, dan 1,65%, dengan dominan sub variabel hepar (bilirubin). Uji regresi logistik memperlihatkan sub variabel neurologi, kardiovaskular, dan respirasi memberikan hubungan bermakna terhadap mortalitas dengan RO 4,58, 2,24, dan 1,47. Sub variabel lain yang berpengaruh antara lain AKI, sepsis, dan penyakit kronis dengan RO 8,14, 3,89 dan 2,42.

Simpulan : CSOFA lebih valid dalam memperkirakan mortalitas pasien di ICU RSUP Sanglah Denpasar, karena mempunyai nilai diskriminasi yang lebih baik dan missing value yang lebih sedikit dibandingkan dengan sistem skoring APACHE II dan SOFA

Keywords
Sistem skoring; APACHE II; SOFA; CSOFA; AuROC; missing value

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