Pengaruh pemberian ubi jalar ungu (Ipomoea batatas L.Poir) terhadap kadar superoksida dismutase (SOD) tikus wistar jantan (Rattus Norvegicus) yang dipapar asap rokok

Alfreda Sabrina Widyanti; Martha Ardiaria; Nurmasari Widyastuti

doi:10.14710/jgi.8.1.45-50

DOI: https://doi.org/10.14710/jgi.8.1.45-50

Pengaruh pemberian ubi jalar ungu (Ipomoea batatas L.Poir) terhadap kadar superoksida dismutase (SOD) tikus wistar jantan (Rattus Norvegicus) yang dipapar asap rokok

Alfreda Sabrina Widyanti, Martha Ardiaria

, Nurmasari Widyastuti

Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Indonesia

Received: 30 Jul 2019; Published: 6 Feb 2020.

BibTex Citation Data :

@article{JGI24684,
    author = {Alfreda Widyanti and Martha Ardiaria and Nurmasari Widyastuti},
    title = {Pengaruh pemberian ubi jalar ungu (Ipomoea batatas L.Poir) terhadap kadar superoksida dismutase (SOD) tikus wistar jantan (Rattus Norvegicus) yang dipapar asap rokok},
    journal = {Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition)},
  volume = {8},
    number = {1},
    year = {2020},
    keywords = {Purple fleshed sweet potato; SOD; oxidative stress},
    abstract = {   Background   : Cigarette smoke exposure is one of the source of free radicals that causes oxidative stress and decreases superoxide dismutase (SOD) level. Purple fleshed sweet potato is a type of food that contains antioxidants to neutralize oxidative stress.       Objectives   :   To study the effect of purple fleshed sweet potato on superoxide dismutase (sod) level on rats exposed to cigarette smoke.       Methods   : This was a true experimental study with a post-test randomized control group design. The rats were randomized into 4 groups (6 rats in each group). The negative control group (K-) was treated with standard diet; the positive control group (K+) was treated with cigarette smoke exposure and standard diet; the treatment 1 (P1) group was treated with standard diet and purple fleshed sweet potato with the dose of 8 g / 200 g bw/day, and the treatment 2 (P2) group was treated with cigarette smoke exposure and purple fleshed sweet potato with the dose of 8 g /200 g bw/day.       Results:      There was a significant difference of SOD levels in each group (p=0.00) except between group K- and P1. Giving purple fleshed sweet potatoes increased SOD levels as much as 85.81±4.59 (P1). The K+ group had the lowest SOD level 22.34±3.98. The SOD level for K- group and P2 group was 82.27±4.59 and 67.73±6.68 respectively.       Conclusion   : The highest SOD level is on the treatment 1 group which is administered with purple fleshed sweet potato.    },
   issn = {2338-3119},   pages = {45--50}  doi = {10.14710/jgi.8.1.45-50},
    url = {https://ejournal.undip.ac.id/index.php/jgi/article/view/24684}
}

Citation Format:

Abstract

Background: Cigarette smoke exposure is one of the source of free radicals that causes oxidative stress and decreases superoxide dismutase (SOD) level. Purple fleshed sweet potato is a type of food that contains antioxidants to neutralize oxidative stress.

Objectives: To study the effect of purple fleshed sweet potato on superoxide dismutase (sod) level on rats exposed to cigarette smoke.

Methods: This was a true experimental study with a post-test randomized control group design. The rats were randomized into 4 groups (6 rats in each group). The negative control group (K-) was treated with standard diet; the positive control group (K+) was treated with cigarette smoke exposure and standard diet; the treatment 1 (P1) group was treated with standard diet and purple fleshed sweet potato with the dose of 8 g / 200 g bw/day, and the treatment 2 (P2) group was treated with cigarette smoke exposure and purple fleshed sweet potato with the dose of 8 g /200 g bw/day.

Results: There was a significant difference of SOD levels in each group (p=0.00) except between group K- and P1. Giving purple fleshed sweet potatoes increased SOD levels as much as 85.81±4.59 (P1). The K+ group had the lowest SOD level 22.34±3.98. The SOD level for K- group and P2 group was 82.27±4.59 and 67.73±6.68 respectively.

Conclusion: The highest SOD level is on the treatment 1 group which is administered with purple fleshed sweet potato.

Fulltext View|Download

Keywords: Purple fleshed sweet potato; SOD; oxidative stress

Funding: Indofood Riset Nugraha

Article Metrics:

Article Info

Section: Articles

Language : EN

In Vol 8, No 1 (2019)

Recent articles

Efek konsumsi yogurt terhadap glukosa darah puasa pada penyandang diabetes melitus tipe 2 Pengaruh lama mengunyah terhadap kadar glukosa postprandial dewasa obesitas Korelasi kadar hepcidin dan asupan makanan dengan serum transferrin reseptor dan hemoglobin pada remaja stunted overweight More recent articles

Most cited articles

Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus) Keragaman pangan, pola asuh makan dan kejadian stunting pada balita usia 24-59 bulan Karakteristik makanan pendamping ASI balita yang disubstitusi dengan tepung ikan lele dan labu kuning Kadar seng dan kadar malondialdehyde pada penderita multi drug resistant tuberculosis dan tuberkulosis sensitif Tepung ulat sagu (Rhyinchophorus ferrugineus) imunomodulator Nitric Oxide (NO) sirkulasi mencit terapi antimalaria standar More cited articles

Marimuthu S. Oxidative and Antioxidant Status in Depressive Disorder Pathology. E-Jurnal Medika Udayana.2013;2(11):1-9
Infodatin Kemenkes RI. Infodatin Hari Tanpa Tembakau Sedunia. Infodatin Pusat Data dan Informasi Kementerian Kesehatan RI (Perilaku Masyarakat Indonesia) berdasarkan Risekesdas 2007 dan 2013. 2013.1–11
Fitria, Triandhini RR, Mangimbulude JC, Karwur FF. Merokok dan Oksidasi DNA. Sains Med. 2013;5(2):113–20
Werdhasari A. Peran Antioksidan Bagi Kesehatan. J Biomedik Medisiana Indones.2014;3(2): 59-68
Ighodaro OM, Akinloye OA. First Line Defence Antioxidants-Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GPX): Their Fundamental Role in The Entire Antioxidant Defence Grid. Alexandria J Med.2017;54(4):287-293
Widyaningsih W, Sativa R, Primardiana I. Efek Antioksidan Ekstrak Etanol Ganggang Hijau (Ulva lactuca L .) Terhadap Kadar Malondialdehid (MDA) dan Aktivitas Enzim Superoksida Dismutase (SOD) Hepar Tikus yang Diinduksi CCl 4 Antioxidant Effect of Ethanolic Extract of Green Algae (Ulva lactuca L.) Media Farm. 2015;4:163–75
Koswara S. Teknologi Pengolahan Umbi-Umbian Bagian 5 : Pengolahan Ubi Jalar. Modul. 2001;34
Husna N El, Novita M, Rohaya S. Anthocyanins Content and Antioxidant Activity of Fresh Purple Fleshed Sweet Potato and Selected Products. Agritech. 2013;33(3):296–302
Yang J, Gadi RL. Effects of Steaming and Dehydration on Anthocyanins, Antioxidant Activity, Total Phenols and Color Characteristics of Purple-Fleshed Sweet Potatoes (Ipomoea batatas). American Journal of Food Technology. 2008;3(4):224-234
Trisnawan MH. Pengaruh pemberian ubi ungu (Ipomea Batatas. L) Terhadap Kadar Enzim Katalase Hepar dan Otak pada Tikus yang Diberikan Minyak Jelantah [skripsi]. Semarang: Fakultas Kedokteran Universitas Diponegoro; 2014
Zheng Y, Shan Q, Lu J, Li J, Zhou Z, Hu B, et al. Purple sweet potato color ameliorates cognition deficits and attenuates oxidative damage and inflammation in aging mouse brain induced by D-galactose. J Biomed Biotechnol. 2009;2009(2):1-7
Chiolero A, Faeh D, Paccaud F, Cornuz J. Consequences of smoking for body weight, body fat distribution,and insulin resistance. Am J Clin Nutr 2008;87:801–9
Kamceva G, Arsova-Sarafinovska Z, Ruskovska M, Kamoeva-Panova L, Stikova E. Cigarette Smoking and Oxidative Stress in Patients with Coronary Artery Disease. Macedonian Journal of Medical Sciences. 2016; 4(4): 636–640
Avelar TMT, Storch AS, Castro LA. Oxidative stress in the pathophysiology of metabolic syndrome: which mechanisms are involved?. Journal Bras Patol Med Lab. 2015;51(4):232
Jawi IM, Wita IW, Suprapta DN. Aqueous Extract of Purple Sweet Potato Tuber Increases SOD And Decreases VCAM-1 Expression By Increasing Nrf2 Expression In The Aortic Endothelia Of Hypercholesterolemic Rabbits. Journal of Biology, Agriculture and Healthcare. 2014;4(10):76-78
Kusumastuty I, Falahia E, Adi P. Pengaruh Daun Ubi Jalar Ungu Terhadap Kadar Superoksida Dismutase Tikus yang Dipapar Asap Rokok. Indonesian Journal of Human Nutrition. 2014;1(2):128-134
Husna NE, Novita M, Rohaya S. Kandungan Antosianin dan Aktivitas Antioksidan Ubi Jalar Ungu Segar dan Produk Olahannya. Agritech. 2013;33(3):296-301
Kaspar KL, Park JS, Brown CR, Mathison BD, Navare DA, Chew BP. Pigmented Potato Consumption Alters Oxidative Stress and Inflammatory Damage in Men. The Journal of Nutrition. 2010;141(1):108-11

Last update:

The Effects of Black Garlic on Ovarian Malondialdehyde, Oviduct Muscle, and Endometrial Arterioles in Smoke-Exposed Rats
Noni Fidya Ayu Anandasari, Novalia Kridayanti, Ni Ketut Devy Kaspirayanthi, Tatit Nurseta, Tri Yudani Mardining Raras, Husnul Khotimah, Subandi Reksohusodo, Kenty Wantri Anita, Hendy Setyo Yudhanto. JURNAL INFO KESEHATAN, 22 (2), 2024. doi: 10.31965/infokes.Vol22.Iss2.1533
Analysis of the Effect of Black Garlic (Allium sativum) Extract on Ovarian Follicular Atresia, Endometrial VEGF Expression, and Fallopian Tube Epithelial Cell Count in Rats (Rattus norvegicus) Exposed to Cigarette Smoke
Novalia Kridayanti, Noni Fidya Ayu Anandasari , Ni Ketut Devy Kaspirayanthi, Tatit Nurseta, Tri Yudani Mardining Raras, Husnul Khotimah, Subandi Reksohusodo, Aina Angelica, Kenty Wantri Anita, Hendy Setyo Yudhanto. JURNAL INFO KESEHATAN, 22 (2), 2024. doi: 10.31965/infokes.Vol22.Iss2.1535

Last update: 2024-11-21 03:44:53

No citation recorded.

Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) is published under licensed of a CC BY-SA Creative Commons Attribution-ShareAlike 4.0 International License

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) and Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro as publisher of the journal.

Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc., will be allowed only with a written permission from Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition).

Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition), Faculty of Medicine, Universitas Diponegoro, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Indonesian Journal of Nutrition are sole and exclusive responsibility of their respective authors and advertisers.