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Clients’ Knowledge and Attitudes Toward Pre-Exposure Prophylaxis at Puskesmas Andalas, Makassar

*Muhammad Arsyad Rahman orcid scopus publons  -  Department of Health Promotion and Behavioral Sciences, Faculty of Public Health, Hasanuddin University, Indonesia
Muhammad Rachmat orcid  -  Department of Health Promotion and Behavioral Sciences, Faculty of Public Health, Hasanuddin University, Indonesia

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Abstract

Background: Pre-exposure prophylaxis (PrEP) is a highly effective strategy for preventing HIV, especially among high-risk groups such as injecting drug users, transgender individuals, sex workers, and men who have sex with men (MSM). In Indonesia, where HIV continues to pose a significant public health challenge, PrEP has the potential to decrease new infections. However, knowledge about PrEP among its users is limited. This study aims to investigate the relationship between users’ knowledge, attitudes, and adherence to PrEP, as well as their satisfaction with services, to design targeted interventions that address misconceptions, reduce stigma, and encourage long-term PrEP use. By offering insights into the experiences of PrEP users, the research seeks to improve PrEP accessibility, acceptability, and effectiveness, contributing to global efforts to end the HIV epidemic.

Method: 200 registered PrEP clients in Puskesmas Andalas participated in this cross-sectional study. Structured questionnaires covering demographics, PrEP utilization, attitudes toward PrEP, and knowledge about PrEP were employed to gather data. The data were analyzed using descriptive statistics and chi-squared testing, considering p<0.05 as statistically significant.

Result: The study results show that 56.5% of participants knew enough about PrEP, while 58.5% held favorable opinions about using it. However, attitudes (p=0.135) and knowledge (p=0.062) showed no discernible effects on PrEP use. The findings suggest that PrEP uptake may be more significantly influenced by factors such as accessibility, pricing, and social stigma, even though education and positive attitudes remain crucial. The study concludes that increasing PrEP utilization among high-risk populations requires comprehensive strategies that tackle these barriers.

 

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Keywords: HIV prevention;Indonesia;pre-exposure prophylaxis;PrEP utilization;public health

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  1. UNAIDS. Global HIV & AIDS statistics – Fact sheet 2020. Joint United Nations Programme on HIV/AIDS [Internet]. 2020. Available from: https://www.unaids.org/en/resources/fact-sheet
  2. WHO. WHO recommends the use of Pre-Exposure Prophylaxis (PrEP) for the prevention of HIV infection. World Health Organization [Internet]. 2021. Available from: https://www.who.int/news-room/detail/2021
  3. Grant, R.M., Lama, J.R., Anderson, P.L., McMahan, V., Liu, A.Y., Vargas, L., et al. Pre-exposure chemoprophylaxis for HIV prevention in men who have sex with men. New England Journal of Medicine. 2010;363(27):2587-2599
  4. Baeten JM, Donnell D, Ndase P, Mugo NR, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. New England Journal of Medicine. 2012;367(5):399-410
  5. Amico KR, Mansoor LE, Corneli A, et al Understanding adherence to Pre-Exposure Prophylaxis (PrEP): A literature review and considerations for future research. Journal of the International Association of AIDS Service Providers. 2014;59(Suppl 1):S55–S60
  6. Ngure K, Heffron R, Curran K, et al. Direct adherence monitoring and drug concentration calculations in an HIV pre-exposure prophylaxis demonstration project in Kenya. Journal of the International AIDS Society. 2016:19(6S6):1-8
  7. F Alves R. The relationship between health-related knowledge and attitudes and health risk behaviours among Portuguese university students. Glob Health Promot. 2024 Mar;31(1):36-44
  8. Aidoo-Frimpong G, Wilson K, Przybyla S. Factors influencing pre-exposure prophylaxis uptake among current users: A qualitative study. J HIV AIDS Soc Serv. 2020;19(3):252-262
  9. Mayer KH, Krakower DS. Editorial comment: Pre-exposure prophylaxis for HIV—Clinical guidelines and the role of health care providers. Clinical Infectious Diseases. 2015;60(4):519-521
  10. Bekker LG, Wood R. The politics of prevention: Pre-exposure prophylaxis in South Africa. Current Opinion on HIV and AIDS. 2014;9(4):364-369
  11. Eakle R, Gomez GB, Naicker N, et al. High acceptance of HIV pre-exposure prophylaxis among a diverse sample of adolescents in South Africa. AIDS and Behavior. 2017;21(7):1980-90
  12. Murray K, Baral S, Beyrer C. Barriers to PrEP use and the role of health care providers. Global Health Action. 2019;12(1):1558035
  13. Putra DS, Atmadani RN, Hidayati IR. The relationship between the level of knowledge of HIV/AIDS sufferers and compliance with taking antiretroviral drugs in primary health services in Malang. Journal of HIV/AIDS & Social Services. 2021;20(3):228-245
  14. Chaerizanisasi A. Stress Coping Strategies in HIV/AIDS Patients with Commercial Sex Worker Backgrounds in Makassar. Journal of Social Work and Social Services. 2023;4(2):93-103
  15. Eisingerich AB, Wheelock A, Gomez GB, et al. Attitudes and acceptance of PrEP among key populations in Asia. AIDS and Behavior. 2021;25(6):1858-71
  16. Putra IGNE, Isa ML, Febrianto T. Stigma terhadap pengguna PrEP di kalangan tenaga kesehatan di Bali. Jurnal Kedokteran Brawijaya. 2023;35(1):12-20
  17. Liu AY, Cohen SE, Vittinghoff E, et al. Adherence and drug detection in a PrEP demonstration project. Journal of Acquired Immune Deficiency Syndromes. 2023;4(4):393-400
  18. Wongkanya R. PrEP knowledge and stigma among Thai transgender women. PLOS ONE. 2022;17(5):e0268123
  19. Haryono B, Susanto T. Healthcare provider stigma toward PrEP users in Jakarta. BMC Public Health. 2023;23(1):456
  20. Gupta S. Cost as a barrier to PrEP use in India. Journal of Virus Eradication. 2022;8(1):100063
  21. Sari DP. Stigma struktural terhadap pengguna PrEP di Puskesmas Indonesia. Jurnal Epidemiologi Kesehatan Indonesia. 2021;5(2):78-89
  22. Cholli P. Mobile health interventions for PrEP adherence in Africa/Asia. The Lancet HIV. 2023;10(3):e178-e186
  23. Sia D. Peer-led PrEP education for MSM in Malaysia. AIDS Education and Prevention. 2022;34(6):491-505
  24. Kurniawati EA Evaluasi program PrEP di klinik swasta Bali. Jurnal Kedokteran Brawijaya. 2023;36(1):45-53
  25. Putri RM. Persepsi komunitas transgender Makassar terhadap PrEP. Indonesian Journal of Public Health. 2023;18(2):234-247
  26. Saputra AB. Analisis kebijakan akses PrEP di Jawa Timur. Jurnal Kebijakan Kesehatan Indonesia. 2022;11(3):156-165
  27. Dharmayanti I. Faktor determinan kepatuhan PrEP pada WPS di Surabaya. Media Penelitian dan Pengembangan Kesehatan. 2021;31(4):289-300
  28. Trickey A. Global review of PrEP implementation challenges. The Lancet HIV. 2023;10(5):e324-e335
  29. Wulandari LPL. Systematic review of PrEP studies in ASEAN. BMC Infectious Diseases. 2022;22(1):789
  30. Surya A. PrEP awareness among transgender women in Jakarta: A mixed-methods study. AIDS and Behavior. 2023;27(2):512-525
  31. Widyanthini D. Barriers to PrEP access in Bali's primary health centers. BMC Public Health. 2022;22(1):1890
  32. Thaipisuttikul P. PrEP implementation challenges in Thailand: Healthcare provider perspectives. PLOS ONE. 2023;18(4):e0284123
  33. Rahmadi A. Religious stigma and PrEP acceptability among MSM in Aceh, Indonesia. Culture, Health & Sexuality. 2021;23(8):1120-35
  34. Gupta S. Cost-effectiveness of PrEP in low-resource settings: Evidence from India. The Lancet HIV. 2023;10(6):e385-e394
  35. Phanuphak N. Peer-led PrEP education for Thai MSM: A randomized controlled trial. Journal of the International AIDS Society. 2022;25(3):e25983
  36. Andriani S. Mobile health interventions for PrEP adherence in Surabaya. International Journal of STD & AIDS. 2023;34(5):332-41
  37. Prasetio R. "I fear judgment more than HIV": Stigma among PrEP users in Yogyakarta. Qualitative Health Research. 2021;31(10):1856-70
  38. Tan D. PrEP implementation in Muslim-majority countries: A systematic review. AIDS Care. 2023;35(4):456-68
  39. Dubov A, Galbo P Jr, Altice FL, Fraenkel L. Stigma and Shame Experiences by MSM Who Take PrEP for HIV Prevention: A Qualitative Study. Am J Mens Health. 2018 Nov;12(6):1843-1854

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