Alternatif Penggunaan Ca(OH)2 dalam Daur Ulang Trietilamin pada Pembuatan Trihidrat Ampisilin dan Amoksisilin

Meiny Suzery; Dewi Meliati Agustini; Agus Supriyanto

doi:10.14710/jksa.1.1.3-10

DOI: https://doi.org/10.14710/jksa.1.1.3-10

Alternatif Penggunaan Ca(OH)2 dalam Daur Ulang Trietilamin pada Pembuatan Trihidrat Ampisilin dan Amoksisilin

Meiny Suzery¹

, Dewi Meliati Agustini¹, Agus Supriyanto²

¹Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University, Indonesia

²Laboratorium Quality Assurance, PT Sandoz Biochemie Farma Indonesia, Indonesia

Published: 28 Feb 1998.

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Abstract

Cairan induk dari pembuatan ampisilin trihidral (eks. AMP) dan amoksisilin trihidrat (eks. AMX) mengandung garam trietilammonium hidroklorida (TEA-HCI). Telah dilakukan regenerasi garam tersebut menjadi TEA dengan NaOH 48% menghasilkan garam anorganik terlarut (ROI) yang tinggi (±800-1000 kg/hari) dalam air limbah olahan. Dalam penelitian ini telah dicoba mengganti basa dengan Ca(OH)₂ dan campuran Ca(OH )-NaOH 48%. Cairan induk dari sintesis (ML) dan dari bagian daur uiang (FML), baik eks AMP/AMX masa produksi IV-VI dicoba dengan 3 perlakuan. Hasil penelitian menunjukkan bahwa penggunaan Ca(OH)₂ lebih sedikit menggunakan basa dan lebih kecil harga ROI-nya, disamping menunjukkan kualitas TEA-1 dan kualitas limbah yang sama dengan metode yang telah dikenal.

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Keywords: Ammonium; regenerasi

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Section: Research Articles

Language : ID

In Vol 1, No 1 (1998): Volume 1 Issue 1 Year 1998

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