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Directional Model of Health-Related Quality of Life After Percutaneous Coronary Intervention: A Structural Equation Model Analysis

*Emil Huriani orcid scopus  -  Department of Medical-Surgical and Emergency Nursing, Faculty of Nursing, Universitas Andalas, Indonesia
Fitri Mailani orcid  -  Department of Medical-Surgical and Emergency Nursing, Faculty of Nursing, Universitas Andalas, Indonesia
Open Access Copyright (c) 2026 by the Authors, Published by Department of Nursing, Faculty of Medicine, Universitas Diponegoro
Creative Commons License This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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Abstract

Background: Although percutaneous coronary intervention (PCI) improves survival and clinical outcomes in patients with acute coronary syndrome (ACS), many patients continue to experience impaired health-related quality of life (HRQoL). However, the direct determinants and mediating pathways influencing HRQoL among patients with ACS following PCI remain incompletely understood.

Purpose: This study aimed to test the relationships among determinants of HRQoL based on the revised Wilson and Cleary’s model in patients with ACS following PCI.

Methods: This cross-sectional study involved 240 patients recruited through consecutive sampling. Data were collected using the Cardiac Self-Efficacy Scale, Fatigue Assessment Scale, Seattle Angina Questionnaire-7, Depression Anxiety Stress Scale 21,  Social Functioning Questionnaire, and MacNew Quality of Life Questionnaire. Structural equation modeling was performed with SmartPLS version 3.2.7.

Results: Self-efficacy, fatigue, anxiety, and social functioning had significant direct effects on HRQoL (β = 0.276, β = -0.151, β = -0.152, and β = 0.307, respectively; p < 0.05). Social functioning had the greatest direct effect (β = 0.307, f2= 0.219), whereas self-efficacy had the greatest total effect on HRQoL (β = 0.789, f2= 0.166).

Conclusion: Self-efficacy, fatigue, anxiety, and social functioning were significant determinants of HRQoL in patients with ACS following PCI. These findings may inform comprehensive patient assessment and the development of targeted, patient-centered nursing care strategies to improve HRQoL.

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Keywords: Acute coronary syndrome; quality of life; revised Wilson and Cleary model; self-efficacy; structural equation modeling
Funding: Faculty of Nursing Universitas Andalas (Research Grant No. 30/UN16.13D/ XIII/KPT/2022)

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