Changes in Sexuality of Castration-Resistant Prostate Cancer Patients under Hormone Therapy in Japan: A Case Study

Yoshiyuki Kashiwagi, Shige Kakinohan
DOI: 10.14710/nmjn.v6i2.9901


Background: Hormone therapy is an important treatment for male patients with prostate cancer. However, it can produce changes in the genitalia and sexuality of the patients.

Purpose: This study aimed to investigate the relations between changes in male genitalia and sexuality in the castration-resistant prostate cancer patients. It also proposed concrete interventions to ease pain and fear towards body image changes.

Methods: This study used a descriptive qualitative design. The subjects were two castration-resistant prostate cancer patients undergoing chemotherapy and endocrine therapy. The data were collected through semi-structured interviews and analyzed using verbatim reports and content analysis.

Results: The study indicated that the effects of hormone therapy treatment on the sexuality were largely categorized as: “surprises and anxieties about the shrinkage of male genitalia”, “masculinity loss”, “difficulty adapting the situation”, and “connection with others”.

Conclusion: It became clear that the prostate cancer patients had pains not only for prognosis, but also for physical changes, relationship changes with others and sexuality changes through their treatments.

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Prostate cancer; chemotherapy; hormone therapy; sexuality


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