Perbandingan Kadar Substansi P Serum pada Pasien Pre dan Post Operasi Tiroid yang Diberi Analgetik Bupivakain 0,25% dengan Teknik Bilateral Superficial Cervical Plexus Block (BSCPB)

*Satrio Adi Wicaksono  -  Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
C O Harahap  -  Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
Doso Sutiyono  -  Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
Himawan Sasongko  -  Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
Edward Kurnia Setiawan Limijadi  -  Departemen Patologi Klinik, Fakultas Kedokteran, Universitas Diponegoro, Indonesia
Published: 1 Mar 2017.
Open Access
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Abstract

Latar belakang: Operasi tiroid dapat menyebabkan rasa sakit sehingga untuk mencegah masalah ini dengan berbagai modalitas, seperti anestesi regional bilateral superficial cervical plexus block (BSCPB) dengan menggunakan bupivakain 0,25% yang dikombinasikan dengan anestesi umum.

Metode: Penelitian ini merupakan penelitian klinis acak tersamar ganda dengan jumlah sampel 36 pasien. Sampel dibagi kedalam 2 kelompok yang diberikan anestesi regional melalui teknik BSCPB dengan kelompok perlakuan diberikan bupivakain 0,25% dibandingkan dengan kelompok kontrol yang diberikan NaCl 0,9% terhadap kadar substansi P serum pre dan post operasi pada pasien yang menjalani operasi tiroid.

Hasil: Data penelitian diperoleh subjek laki-laki sebanyak 7 (19,4%) orang dan subjek  perempuan  sebanyak  29  (80,6%)  orang. Data substansi P post operasi kelompok  control dibandingkan kelompok perlakuan  didapatkan perbedaan bermakna  (p = 0,001). Substansi P pre operasi dibandingkan substansi P post operasi kelompok perlakuan didapatkan perbedaan bermakna (p = 0,004). 

Simpulan: Pemberian bupivakain konsentrasi 0,25% melalui teknik BSCPB terbukti menurunkan kadar substansi P serum post operasi.

 

 

Keywords: Substansi P serum; operasi tiroid; bilateral superficial cervical plexus block

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Article Info
Section: Penelitian
Language: ID
In Vol 9, No 1 (2017): Jurnal Anestesiologi Indonesia
Statistics: 601 679
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