Peran Plasmafaresis pada Terapi Pasien Sepsis dengan Myasthenia Gravis

Ahmad Imron; Dita Aditianingsih; Yohanes W George

doi:10.14710/jai.v5i3.6311

DOI: https://doi.org/10.14710/jai.v5i3.6311

Peran Plasmafaresis pada Terapi Pasien Sepsis dengan Myasthenia Gravis

Ahmad Imron^{1, 2} , Dita Aditianingsih^{3, 4}, Yohanes W George^{5, 4}

¹Bagian Anestesi dan Terapi Intensif/ Rumah Sakit Mitra Keluarga , Indonesia

²Bekasi, Indonesia

³Bagian Anestesi dan Terapi Intensif, Fakultas Kedokteran,, Indonesia

⁴ Universitas Indonesia, Indonesia

⁵ Bagian Anestesi dan Terapi Intensif, Fakultas Kedokteran, , Indonesia

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Published: 1 Nov 2013.

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Abstract

Pendahuluan : Plasmapheresis berpotensi untuk menghilangkan mediator berbahaya atau beracun dari sirkulasi . Plasmapheresis telah menunjukkan peningkatan keluaran yang bermakna pada penyakit autoimun . Kemanjuran theurapetic dan keamanan plasmapheresis dalam pengobatan pasien di sepsis berat dan syok septik telah dipelajari .

Kasus : Seorang perempuan berusia 18 tahun didiagnosis dengan gagal nafas karena myasthenia gravis dan sepsis berat akibat pneumonia . Dia dirujuk dari rumah sakit lain setelah kegagalan obat antikolinesterase untuk mengobati gejala dari myasthenia gravis. x foto thorax menunjukkan infiltrat di paru-paru kanan paracardial dan basal . Terapi yang diberikan selama di ICU adalah antibiotik , obat-obatan suportif, dan plasmapheresis dilakukan selama 4 kali . Setelah antibiotik yang sesuai diberikan dan plasmapheresis selesai, pasien menunjukkan perbaikan kekuatan otot. Pasien berhasil disapih dari ventilator pada hari ke - 9 , dan kembali ke bangsal di hari - 10 .

Ringkasan : Plasmapheresis memainkan peran penting dalam pengobatan myasthenia gravis dengan sepsis . Plasmapheresis digunakan untuk menghapus berbagai factor pemicu dalam plasma , seperti antibodi , imunoglobulin abnormal dan kompleks imun dalam sirkulasi

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Keywords: myasthenia gravis; plasmapharesis; terapi intensif

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Section: Original Articles

Language : ID

In Vol 5, No 3 (2013): JAI (Jurnal Anestesiologi Indonesia)

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