DOI: https://doi.org/10.14710/jai.v0i0.65043

The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients

1Doctoral Study Program in Medical and Health Sciences, Faculty of Medicine, Diponegoro University, Semarang, Indonesia

2Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University, Semarang, Indonesia

3Department of Neurology, Faculty of Medicine, Diponegoro University, Semarang, Indonesia

4 Department of Surgery, Faculty of Medicine, Diponegoro University, Semarang, Indonesia

View all affiliations
Received: 11 Jul 2024; Revised: 29 Nov 2024; Accepted: 30 Nov 2024; Published: 30 Nov 2024.
Open Access Copyright 2024 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Citation Format:
Cover Image
Abstract

Background: Oral carbohydrate administration reduces post-operative insulin resistance and improves post-operative recovery. Sugar water and maltodextrin are oral carbohydrates that can be given to enhanced recovery after caesarean surgery (ERACS) patients.

Objective: To compare the effect between pre-operative maltodextrin treatment and sugar water treatment on random blood glucose (RBG) levels in enhanced recovery after caesarean section (ERACS) patients.

Methods: A randomized control study with pre-test and post-test design was used on 48 patients who underwent ERACS surgery at Dr. Kariadi hospital Semarang Indonesia and met the inclusion and exclusion criteria. Study subjects were divided into two groups: a pre-operative maltodextrin treatment group (n=24) and a pre-operative sugar water control group (n=24). RBG levels were checked with point-of-care testing (POCT) at soon before surgery and at 2 hours after surgery. Mann-Whitney test was used to analyse the difference of RBG levels between group with Maltodextrin and group with sugar water. Wilcoxon test was used to analyse the difference of RBG levels before surgery (pre-operative RBG) and 2 hours after surgery (post-operative RBG). The p value of <0.05 was considered as statistically significant.

Result: There were significant lower RBG levels in group with pre-operative maltodextrin treatment compared to group with pre-operative sugar water at soon before surgery (pre-operative) (83.5 ± 9.73 vs 96.2 ± 12.99 mg/dL, p=0.003) and at 2 hours post-operative (101.7 ± 15.81 vs 118.9 ± 28.38, p=0.035) in ERACS patients.

Conclusion: If confirmed by further studies, pre-operative maltodextrin administration might provide better outcome in reducing post-operative catabolic status by reducing post-operative insulin resistance and improving RBG levels before and after ERACS compared to sugar water control.

Note: This article has supplementary file(s).

Fulltext View|Download |  common.other
Ethical Clearance
Subject
Type Other
  Download (317KB)    Indexing metadata
 common.other
Graphical Abstract
Subject
Type Other
  View (687KB)    Indexing metadata
 common.other
Copyright Transfer Agreement
Subject
Type Other
  Download (46KB)    Indexing metadata
Keywords: carbohydrate; caesarean surgery; ERACS; maltodextrin; random blood glucose

Article Metrics:

Article Info
Section: Original Articles
Language : EN
Recent articles
The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients Enteral Nutrition Tolerability Assessment in Septic Shock Patients in The ICU of RSUP H. Adam Malik Medan Comparison of Laryngeal Mask Airway and Endotracheal Tube on Intraocular Pressure in Vitrectomy Adductor Canal Block (ACB) as an Adequate Analgesia Post Anterior Cruciate Ligament Repair Anesthetic Choice and Management in Cesarean Section for a Patient with Post Laminectomy and Inferior Stabilization: A Case Report A 23-Year-Old Woman with Cerebellopontine Tumor Angle Sectio Caesaria Trans-peritoneal Profunda Surgery Over Oligohydramnios Indication Literature Review: Palliative Care in Intensive Care Units Bronchial Toilets in Sepsis Patients Treated in The Intensive Care Unit (ICU): A review On Indications and Complications Prevention and Management of Stress Ulcers in Critically ill Patients More recent articles
Most cited articles
Midazolam Intravena Dosis Rendah Tidak Mempengaruhi Nitric Oxide Intraperitoneal Mencit Balb/C Yang Terpapar Lipopolisakarida Patofisiologi Penyakit Jantung Koroner More cited articles
  1. Aryasa TEM, Rehatta NM, Isngadi I, Sari D, Lestari MI, Liberty IA, et al. Obstetric anesthesia services profile in cesarean section in Indonesian population: A prospective, observational, multicenter Rstudy. Bali J Anaesthesiol. 2023;7(4):215–9
  2. Ituk U, Habib AS. Enhanced Recovery After Cesarean Delivery. F1000Res. 2018:7: F1000 Faculty Rev–513
  3. Noblett SE, Watson DS, Huong H, Davison B, Hainsworth PJ, Horgan AF. Pre-Operative Oral Carbohydrate Loading in Colorectal Surgery: A Randomized Controlled Trial. Colorectal Dis. 2006;8(7):563–9
  4. Singh J. Preoperative Oral Carbohydrate Drink Improves Surgical Outcome. MOJ Surg. 2018;6(2):72–3
  5. Awad S, Constantin-Teodosiu D, Constantin D, Rowlands BJ, Fearon KCH, Macdonald IA, et al. Cellular Mechanisms Underlying the Protective Effects of Preoperative Feeding: A Randomized Study Investigating Muscle and Liver Glycogen Content, Mitochondrial Function, Gene and Protein Expression. Ann Surg.2010;252(2):247–53
  6. Awad S, Fearon KCH, Macdonald IA, Lobo DN. A Randomized Cross-Over Study of The Metabolic and Hormonal Responses Following Two Preoperative Conditioning Drinks. Nutrition. 2011;27(9):938– 42
  7. Yuill KA, Richardson RA, Davidson HIM, Garden OJ, Parks RW. The Administration of An Oral Carbohydrate-Containing Fluid Prior To Major Elective Upper-Gastrointestinal Surgery Preserves Skeletal Muscle Mass Postoperatively- A Randomised Clinical Trial. Clin Nutr. 2005;24(1):32–7
  8. Hausel J, Nygren J, Lagerkranser M, Hellström PM, Hammarqvist F, Almström C, et al. A Carbohydrate-Rich Drink Reduces Preoperative Discomfort in Elective Surgery Patients. Anesth Analg. 2001;93(5):1344–50
  9. Ding T, Deng C-M, Shen X-F, Bai Y-W, Zhang X-L, Liu J-P, et al. Effect of A Carbohydrate-Rich Beverage on Rate of Cesarean Delivery in Primigravidae with Epidural Labor Analgesia: A Multicenter Randomized Trial. BMC Pregnancy Childbirth. 2022;22(1):339
  10. Tzeng HP, Chiu CY, Liu SH, Chiang MT. Improvement of Glycemic Control by a Functional Food Mixture Containing Maltodextrin, White Kidney Bean Extract, Mulberry Leaf Extract, and Niacin-Bound Chromium Complex in Obese Diabetic db/db Mice. Metabolites. 2022;12(8):693
  11. Faria MSM, de Aguilar-Nascimento JE, Pimenta OS, Alvarenga Jr LC, Dock-Nascimento DB, Slhessarenko N. Preoperative Fasting of 2 Hours Minimizes Insulin Resistance and Organic Response to Trauma After Video-Cholecystectomy: A Randomized, Controlled, Clinical Trial. World J Surg. 2009;33(6): 1158–64
  12. Perrone F, da-Silva-Filho AC, Adôrno IF, Anabuki NT, Leal FS, Colombo T, et al. Effects of preoperative feeding with a whey protein plus carbohydrate drink on the acute phase response and insulin resistance. A randomized trial. Nutr J. 2011;10:66
  13. Hofman DL, van Buul VJ, Brouns FJ. Nutrition, Health, and Regulatory Aspects of Digestible Maltodextrins. Crit Rev Food Sci Nutr. 2016;56(12):2091–100
  14. Bogossian PM, Tescaro Piffer ML, Maschietto FB, Martins TR, de Oliveira Araujo DA, Oliveira TM, et al. Effect of maltodextrin supplementation on blood glucose, lactate, insulin, and cortisol levels in horses subjected to submaximal incremental exercise test. Rev Acad Cienc Anim. 2019;17:e17005
  15. Qin H, Ji J, Miao Y, Liu T, Zhao D, Jia Z, et al. Efficacy of the Oral Administration of Maltodextrin Fructose Before Major Abdominal Surgery: A Prospective, Multicenter Clinical Study. World J Surg. 2022 Sep;46(9):2132–40

Last update:

No citation recorded.

Last update: 2024-12-20 00:05:19

No citation recorded.