Chitosan succinate/PVA-PEG Membrane: Preparation, Characterization and Permeation Ability Test on Creatinine

DOI: https://doi.org/10.14710/jksa.21.2.80-84

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Published: 30-04-2018
Section: Research Articles
In Vol 21, No 2 (2018): Volume 21 Issue 2 Year 2018
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Evaluation character of chitosan membrane-succinate / poly vinyl alcohol-poly ethylene glycol (PVA-PEG) were prepared in acetic acid solvent through a phase inversion method has been performed. The study began with the preparation of crosslinked chitosan compounds with succinic acid, followed by preparation into membrane by combining PVA-PEG. Character analysis of the resulting material using FTIR, EDX, TGA, water absorption test, tensile strength, membrane hydrophilicity. The ability of membrane permeation was tested against creatinine. The results showed that the succinate had reacted with chitosan. Chitosan modification through cross link and polymer alloys increases tensile strength and membrane strain of 1.7-2.5 x of pure chitosan membrane. In addition, the modified membrane also has higher water absorption and hydrophilicity values than the unmodified membrane, and this implies the ability of membrane-induced creatinine permeation. Permeable permeation values were 13.8% in chitosan, 24.84% on chitosan-succinate and 25% in chitosan-succinate / PVA-PEG. Chitosan-succinate membranes have the ability to use more than 4x repeated use.

Keywords

chitosan-succinate membranes; poly vinyl alcohol; poly ethylene glycol; permeation ability; creatinine

  1. Retno Ariadi Lusiana  Orcid Scopus Scholar Sinta
    Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University Jl. Prof. Soedarto, SH., Tembalang, Semarang, Indonesia
  2. Vivi Dia Ahmad Sangkota 
    Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University Jl. Prof. Soedarto, SH., Tembalang, Semarang, Indonesia
  3. Sri Juari Santosa  Orcid Scopus Sinta
    Department of Chemistry, Faculty of Mathematics and Natural Sciences, Gadjah Mada University Yogyakarta, Indonesia
  1. Retno Ariadi Lusiana, Dwi Siswanta, Mudasir Mudasir, Preparation of Citric Acid Crosslinked Chitosan/Poly(Vinyl Alcohol) Blend Membranes for Creatinine Transport, Indonesian Journal of Chemistry, 16, 2, (2018) 144-150 http://dx.doi.org/10.22146/ijc.21157
  2. Retno Ariadi Lusiana, Wahyu Putri Protoningtyas, Anugrah Ricky Wijaya, Dwi Siswanta, Mudasir, Sri Juari Santosa, Chitosan-Tripoly Phosphate (CS-TPP) Synthesis Through Cross-linking Process: the Effect of Concentration Towards Membrane Mechanical Characteristic and Urea Permeation, Oriental Journal of Chemistry, 33, 6, (2017) 2913-2919 http://dx.doi.org/10.13005/ojc/330626
  3. Ezequiel S. Costa-Júnior, Edel F. Barbosa-Stancioli, Alexandra A. P. Mansur, Wander L. Vasconcelos, Herman S. Mansur, Preparation and characterization of chitosan/poly(vinyl alcohol) chemically crosslinked blends for biomedical applications, Carbohydrate Polymers, 76, 3, (2009) 472-481 https://doi.org/10.1016/j.carbpol.2008.11.015
  4. Wilma F. van Straaten-Nijenhuis, Feike de Jong, David N. Reinhoudt, Randolph P. Thummel, Thomas W. Bell, Jia Liu, Urea transport through supported liquid membranes using synthetic carriers, Journal of Membrane Science, 82, 3, (1993) 277-283 https://doi.org/10.1016/0376-7388(93)85192-Y
  5. H. M. Fahmy, Moustafa M. G. Fouda, Crosslinking of alginic acid/chitosan matrices using polycarboxylic acids and their utilization for sodium diclofenac release, Carbohydrate Polymers, 73, 4, (2008) 606-611 https://doi.org/10.1016/j.carbpol.2007.12.024
  6. Fathur Al Baani, Retno Ariadi Lusiana, Muhammad Cholid Djunaidi, Pengaruh Agen Pencangkok Heparin terhadap Kemampuan Transpor Kreatinin dan Urea Membran Turunan Kitosan, Jurnal Kimia Sains dan Aplikasi, 20, 2, (2017) 92-94 http://dx.doi.org/10.14710/jksa.20.2.92-94
  7. Magdalena Gierszewska, Jadwiga Ostrowska-Czubenko, Chitosan-based membranes with different ionic crosslinking density for pharmaceutical and industrial applications, Carbohydrate Polymers, 153, (2016) 501-511 https://doi.org/10.1016/j.carbpol.2016.07.126
  8. Nastiti Nastiti, Parsaoran Siahaan, Pengaruh Berat Molekul Kitosan terhadap Efisiensi Enkapsulasi BSA (Bovine Serum Albumin) Menggunakan Agen Crosslink Na-TPP, Jurnal Kimia Sains dan Aplikasi, 18, 3, (2015) 104-109
  9. M. N. Hyder, P. Chen, Pervaporation dehydration of ethylene glycol with chitosan–poly(vinyl alcohol) blend membranes: Effect of CS–PVA blending ratios, Journal of Membrane Science, 340, 1, (2009) 171-180 https://doi.org/10.1016/j.memsci.2009.05.021
  10. Radhakumary C., Nair Prabha D., Reghunadhan Nair C. P., Mathew Suresh, Chitosan‐graft‐poly(vinyl acetate) for hemodialysis applications, Journal of Applied Polymer Science, 125, 3, (2012) 2022-2033 http://dx.doi.org/10.1002/app.36261
  11. Marcel Mulder, J. Mulder, Basic Principles of Membrane Technology, Springer, 1996.
  12. Suneeta Kumari, Sri Hari Kumar Annamareddy, Sahoo Abanti, Pradip Kumar Rath, Physicochemical properties and characterization of chitosan synthesized from fish scales, crab and shrimp shells, International Journal of Biological Macromolecules, 104, (2017) 1697-1705 https://doi.org/10.1016/j.ijbiomac.2017.04.119
  13. Lulu Li, Chong Cheng, Tao Xiang, Min Tang, Weifeng Zhao, Shudong Sun, Changsheng Zhao, Modification of polyethersulfone hemodialysis membrane by blending citric acid grafted polyurethane and its anticoagulant activity, Journal of Membrane Science, 405-406, (2012) 261-274 https://doi.org/10.1016/j.memsci.2012.03.015
  14. Peng-bo Huangfu, Ming Gong, Cunfu Zhang, Shan Yang, Jiang Zhao, Yong-kuan Gong, Cell outer membrane mimetic modification of a cross-linked chitosan surface to improve its hemocompatibility, Colloids and Surfaces B: Biointerfaces, 71, 2, (2009) 268-274 https://doi.org/10.1016/j.colsurfb.2009.02.014
  15. Agustiani Yudi Aryanti, Rum Hastuti, Khabibi Khabibi, Pengaruh Penambahan Polietilen Glikol (PEG) pada Selulosa dalam Serbuk Tongkol Jagung (Zea Mays) terhadap Adsorpsi Ion Logam Timbal (Pb2+), Jurnal Kimia Sains dan Aplikasi, 17, 1, (2014) 1-5 http://dx.doi.org/10.14710/jksa.17.1.1-5
  16. Nita Kusumawati, Septiana Tania, Pembuatan dan Uji Kemampuan Membran Kitosan sebagai Membran Ultrafiltrasi untuk Pemisahan Zat Warna Rhodamin B, Molekul, 7, 1, (2012) 43-52 http://dx.doi.org/10.20884/1.jm.2012.7.1.105