1Department of Chemistry, Faculty of Sciences, Sriwijaya University, Inderalaya 30662, Ogan Ilir, Indonesia
2Department of Parasitology, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia
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@article{JKSA46839, author = {Dasril Basir and Jefri Liasta and Annisa Amelia and Miksusanti Miksusanti and Susilawati Susilawati}, title = {Oliveramine: An Isolated Alkaloid from Fagraea fragrans (Tembesu) Bark}, journal = {Jurnal Kimia Sains dan Aplikasi}, volume = {25}, number = {7}, year = {2022}, keywords = {Fagraea fragrans; bark; dimeric; pyridine; alkaloid}, abstract = {This paper described the progress of phytochemical, especially alkaloids, work on Fagraea fragrans species (tembesu), Loganiaceae. A dimeric-pyridine alkaloid with molecular formula C 20 H 20 O 4 N 2 has been successfully isolated from diethyl ether extracts from this plant’s barks. The alkaloid was explored from diethyl ether extracts using sulphuric acid (2%), then basified with ammonium hydroxide (25%) until the solution had a pH of 10.5. The later solution was extracted again with chloroform. The alkaloid residue was subjected to column chromatography and eluted with 10% acetone in chloroform. The chemical structure of the isolated dimeric-pyridine alkaloid was determined by LCMS/MS, 13 C-NMR, and 1 H-NMR spectroscopies. As a result, the isolated dimeric-pyridine alkaloid was closely similar to the oliveramine alkaloid, and this is also the first report about oliveramine from Fagraea fragrans ( F. Fragrans ).}, issn = {2597-9914}, pages = {264--269} doi = {10.14710/jksa.25.7.264-269}, url = {https://ejournal.undip.ac.id/index.php/ksa/article/view/46839} }
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