skip to main content

Synthesis and Characterization of Zirconium Dioxide Nanoparticles in Various Liquid Media by Nd:YAG Pulse Laser Ablation and Its Antibacterial Application

Department of Physics, Faculty of Sciences and Mathematics, Diponegoro University, Semarang, Indonesia

Received: 18 May 2024; Revised: 9 Sep 2024; Accepted: 23 Sep 2024; Published: 30 Oct 2024.
Open Access Copyright 2024 Jurnal Kimia Sains dan Aplikasi under http://creativecommons.org/licenses/by-sa/4.0.

Citation Format:
Cover Image
Abstract

The issue of antibiotic resistance by bacteria has been studied to develop a new agent to inhibit bacterial activity. Recent studies have reported on nanoparticles promising antibacterial properties. Zirconium dioxide nanoparticles (ZrO2 NPs) have emerged as potential antibacterial agents for gram-negative bacteria. Nevertheless, there remains a gap in research done on producing stable nanoparticles. Additionally, it studies the impact of the liquid environment in the synthesis to keep a small size. In this present work, ZrO2 NPs have been successfully synthesized in various liquids by pulse laser ablation using the Nd:YAG laser. The laser was ablated on the surface of a zirconium metal plate in different liquid media, such as deionized water, ethylene diamine, and chitosan solution. Furthermore, the liquid media used has an effect on the characteristics of ZrO2 NPs and their antibacterial properties. An investigation of scanning electron microscope images reveals that ZrO2 NPs in deionized water, ethylene diamine, and chitosan solutions have a spherical morphology with diameters measuring around 24.33 nm, 19.76 nm, and 15.05 nm, respectively. The antibacterial effect of ZrO2 NPs in chitosan solution against E. coli bacteria is assessed by measuring the diameter of the inhibition zone (DIZ), which has greater colloidal stability than the other liquid media. The findings indicate that the stability and small size of nanoparticles enhance the ability to inhibit the growth of bacteria.

Fulltext View|Download
Keywords: ZrO2 nanoparticles; pulse laser ablation method; antibacterial; E. coli

Article Metrics:

  1. Xin Zhang, Kandasamy Saravanakumar, Anbazhagan Sathiyaseelan, Soyoung Park, Myeong-Hyeon Wang, Synthesis, characterization, and comparative analysis of antibiotics (ampicillin and erythromycin) loaded ZrO2 nanoparticles for enhanced antibacterial activity, Journal of Drug Delivery Science and Technology, 82, (2023), 104293 https://doi.org/10.1016/j.jddst.2023.104293
  2. Hadeel M. Yosif, Buthenia A. Hasoon, Majid S. Jabir, Laser Ablation for Synthesis of Hydroxyapatite and Au NP Conjugated Cefuroxime: Evaluation of Their Effects on the Biofilm Formation of Multidrug Resistance Klebsiella pneumoniae, Plasmonics, 19, 3, (2024), 1085-1099 https://doi.org/10.1007/s11468-023-02053-y
  3. Mukhlis Sanuddin, Medi Andriani, Tiara Angraini, Synthesis and Antibacterial Activity Test of Dibutyl Tin (IV) N-Ethylbenzyl Dithiocarbamate Compound Against Salmonella Thy.Atcc.14028 and Propionibacterium acnes Bacteria, Jurnal Kimia Sains dan Aplikasi, 27, 7, (2024), 300-306 https://doi.org/10.14710/jksa.27.7.300-306
  4. Sonali A. Korde, Premkumar B. Thombre, Sudarshan S. Dipake, Jaiprakash N. Sangshetti, Anjali S. Rajbhoj, Suresh T. Gaikwad, Neem gum (Azadirachta indicia) facilitated green synthesis of TiO2 and ZrO2 nanoparticles as antimicrobial agents, Inorganic Chemistry Communications, 153, (2023), 110777 https://doi.org/10.1016/j.inoche.2023.110777
  5. Ayodeji Precious Ayanwale, Simón Yobanny Reyes-López, ZrO2–ZnO Nanoparticles as Antibacterial Agents, ACS Omega, 4, 21, (2019), 19216-19224 https://doi.org/10.1021/acsomega.9b02527
  6. Ana Qona'ah, Maria Margaretha Suliyanti, Eko Hidayanto, Ali Khumaeni, Characteristics of copper oxide and tin oxide nanoparticles produced by using pulsed laser ablation method and their application as an antibacterial agent, Results in Chemistry, 6, (2023), 101042 https://doi.org/10.1016/j.rechem.2023.101042
  7. Syifa Avicenna, Iis Nurhasanah, Ali Khumaeni, Synthesis of Colloidal Silver Nanoparticles in Various Liquid Media Using Pulse Laser Ablation Method and Its Antibacterial Properties, Indonesian Journal of Chemistry, 21, 3, (2021), 761-768 https://doi.org/10.22146/ijc.60344
  8. Fatkhiyatus Sa’adah, Rizka Zakiyatul Miskiyah, Nurul Hikmantiyah, Ali Khumaeni, Effect of laser repetition rate in the synthesis of colloidal zinc nanoparticles by pulse laser ablation method, Journal of Physics: Conference Series, 1153, (2019), 012069 https://doi.org/10.1088/1742-6596/1153/1/012069
  9. Mohammad Asaduzzaman Chowdhury, Nayem Hossain, Md Golam Mostofa, Md Riyad Mia, Md Tushar, Md Masud Rana, Md Helal Hossain, Green synthesis and characterization of zirconium nanoparticle for dental implant applications, Heliyon, 9, 1, (2023), e12711 https://doi.org/10.1016/j.heliyon.2022.e12711
  10. Thuan Van Tran, Duyen Thi Cam Nguyen, Ponnusamy Senthil Kumar, Azam Taufik Mohd Din, Aishah Abdul Jalil, Dai-Viet N. Vo, Green synthesis of ZrO2 nanoparticles and nanocomposites for biomedical and environmental applications: a review, Environmental Chemistry Letters, 20, 2, (2022), 1309-1331 https://doi.org/10.1007/s10311-021-01367-9
  11. N. C. Horti, M. D. Kamatagi, S. K. Nataraj, M. N. Wari, S. R. Inamdar, Structural and optical properties of zirconium oxide (ZrO2) nanoparticles: effect of calcination temperature, Nano Express, 1, (2020), 010022 https://doi.org/10.1088/2632-959x/ab8684
  12. E. Indrajith Naik, H. S. Bhojya Naik, R. Viswanath, B. R. Kirthan, M. C. Prabhakara, Effect of zirconium doping on the structural, optical, electrochemical and antibacterial properties of ZnO nanoparticles prepared by sol-gel method, Chemical Data Collections, 29, (2020), 100505 https://doi.org/10.1016/j.cdc.2020.100505
  13. Khadijah A. Altammar, A review on nanoparticles: characteristics, synthesis, applications, and challenges, Frontiers in Microbiology, 14, (2023), https://doi.org/10.3389/fmicb.2023.1155622
  14. Ali Khumaeni, Tri Istanti, Eko Hidayanto, Iis Nurhasanah, Characteristics of tin oxide nanoparticles produced by pulsed laser ablation technique in various concentrations of chitosan liquid and their potential application as an antibacterial agent, Results in Engineering, 16, (2022), 100742 https://doi.org/10.1016/j.rineng.2022.100742
  15. M. Tajdidzadeh, B. Z. Azmi, W. Mahmood M. Yunus, Z. Abidin Talib, A. R. Sadrolhosseini, K. Karimzadeh, S. A. Gene, M. Dorraj, Synthesis of Silver Nanoparticles Dispersed in Various Aqueous Media Using Laser Ablation, The Scientific World Journal, 2014, 1, (2014), 324921 https://doi.org/10.1155/2014/324921
  16. Shahab Ahmed Abbasi, Javeria Javed, Hamza Qayyum, Taj Muhammad Khan, Dilawar Ali, Amjad Iqbal, S. Aal, Natasha Nazir, Composite Liquid Media Influence on the Optical and Bactericidal Properties of Silver Nanoparticles Synthesized by Pulsed Laser Ablation in Liquids, Plasmonics, (2024), https://doi.org/10.1007/s11468-024-02443-w
  17. Mujeeb Khan, Mohammed Rafi Shaik, Shams Tabrez Khan, Syed Farooq Adil, Mufsir Kuniyil, Majad Khan, Abdulrahman A. Al-Warthan, Mohammed Rafiq H. Siddiqui, Muhammad Nawaz Tahir, Enhanced Antimicrobial Activity of Biofunctionalized Zirconia Nanoparticles, ACS Omega, 5, 4, (2020), 1987-1996 https://doi.org/10.1021/acsomega.9b03840
  18. Tan Phat Chau, Geetha Royapuram Veeraragavan, Mathiyazhagan Narayanan, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Baskaran Subramani, Kathirvel Brindhadevi, Tipsukon Pimpimon, Surachai Pikulkaew, Green synthesis of Zirconium nanoparticles using Punica granatum (pomegranate) peel extract and their antimicrobial and antioxidant potency, Environmental Research, 209, (2022), 112771 https://doi.org/10.1016/j.envres.2022.112771
  19. M. A. Gondal, Talal F. Qahtan, M. A. Dastageer, Tawfik A. Saleh, Yasin W. Maganda, D. H. Anjum, Effects of oxidizing medium on the composition, morphology and optical properties of copper oxide nanoparticles produced by pulsed laser ablation, Applied Surface Science, 286, (2013), 149-155 https://doi.org/10.1016/j.apsusc.2013.09.038
  20. Giancarlo Dalle Ave, Thomas A. Adams, Techno-economic comparison of Acetone-Butanol-Ethanol fermentation using various extractants, Energy Conversion and Management, 156, (2018), 288-300 https://doi.org/10.1016/j.enconman.2017.11.020
  21. Bailei Li, Jeevithan Elango, Wenhui Wu, Recent Advancement of Molecular Structure and Biomaterial Function of Chitosan from Marine Organisms for Pharmaceutical and Nutraceutical Application, Applied Sciences, 10, 14, (2020), 4719 https://doi.org/10.3390/app10144719
  22. Darius Arndt, Volkmar Zielasek, Wolfgang Dreher, Marcus Bäumer, Ethylene diamine-assisted synthesis of iron oxide nanoparticles in high-boiling polyolys, Journal of Colloid and Interface Science, 417, (2014), 188-198 https://doi.org/10.1016/j.jcis.2013.11.023
  23. Thi Tuong Vy Phan, Duc Tri Phan, Xuan Thang Cao, Thanh-Canh Huynh, Junghwan Oh, Roles of Chitosan in Green Synthesis of Metal Nanoparticles for Biomedical Applications, Nanomaterials, 11, 2, (2021), 273 https://doi.org/10.3390/nano11020273
  24. Kareem H. Jawad, Fatima K. Jamagh, Ghassan M. Sulaiman, Buthenia A. Hasoon, Salim Albukhaty, Hamdoon A. Mohammed, Mosleh M. Abomughaid, Antibacterial and antibiofilm activities of amikacin-conjugated gold Nanoparticles: A promising formulation for contact lens preservation, Inorganic Chemistry Communications, 162, (2024), 112286 https://doi.org/10.1016/j.inoche.2024.112286
  25. Inas S. Mohammed, Duaa Hammoud, Sajidah H. Alkhazraji, Kareem H. Jawad, Buthenia A. Hasoon, Ali Abdullah Issa, Majid S. Jabir, Biosynthesized Graphene Oxide Nanoparticles: In-Vitro Comparative Study for Biomedical Applications, Plasmonics, (2024), https://doi.org/10.1007/s11468-024-02433-y
  26. Kavil Mehta, Swetapuspa Soumyashree, Jalaja Pandya, Parul Singh, Rajesh K. Kushawaha, Prashant Kumar, Satyam Shinde, Jhuma Saha, Prahlad K. Baruah, Impact of viscosity of liquid on nanoparticles synthesized by laser ablation in liquid: An experimental and theoretical investigation, Applied Physics A, 129, 5, (2023), 388 https://doi.org/10.1007/s00339-023-06673-3
  27. Khawla S. Khashan, Majid S. Jabir, Farah A. Abdulameer, Carbon Nanoparticles Prepared by Laser Ablation in Liquid Environment, Surface Review and Letters, 26, 10, (2019), 1950078 https://doi.org/10.1142/s0218625x19500781
  28. Felix Jonathan, Harisma Zaini Ahmad, Khairun Nida, Ali Khumaeni, Characteristics and antibacterial properties of carbon nanoparticles synthesized by the pulsed laser ablation method in various liquid media, Environmental Nanotechnology, Monitoring & Management, 21, (2024), 100909 https://doi.org/10.1016/j.enmm.2023.100909
  29. Agata Kaczmarek, Jacek Hoffman, Jerzy Morgiel, Tomasz Mościcki, Leszek Stobiński, Zygmunt Szymański, Artur Małolepszy, Luminescent Carbon Dots Synthesized by the Laser Ablation of Graphite in Polyethylenimine and Ethylenediamine, Materials, 14, 4, (2021), 729 https://doi.org/10.3390/ma14040729
  30. Kistan Andiyappan, Sathiyamoorthi Ramalingam, Intensification of bio-synthesis of zirconium oxide (ZrO2) nanoparticles derived from novel Crescentia Cujete fruits: Effects on diesel engine characteristics powered by waste engine oil methyl ester-diesel blend, Chemical Engineering and Processing - Process Intensification, 195, (2024), 109642 https://doi.org/10.1016/j.cep.2023.109642
  31. Anthony Singer, Zein Barakat, Subhra Mohapatra, Shyam S. Mohapatra, Chapter 13 - Nanoscale Drug-Delivery Systems: In Vitro and In Vivo Characterization, in: S.S. Mohapatra, S. Ranjan, N. Dasgupta, R.K. Mishra, S. Thomas (Eds.) Nanocarriers for Drug Delivery, Elsevier, 2019, https://doi.org/10.1016/B978-0-12-814033-8.00013-8
  32. Yael N. Slavin, Jason Asnis, Urs O. Häfeli, Horacio Bach, Metal nanoparticles: understanding the mechanisms behind antibacterial activity, Journal of Nanobiotechnology, 15, (2017), 65 https://doi.org/10.1186/s12951-017-0308-z
  33. Nazish Tabassum, Dinesh Kumar, Divya Verma, Raghvendra A. Bohara, M. P. Singh, Zirconium oxide (ZrO2) nanoparticles from antibacterial activity to cytotoxicity: A next-generation of multifunctional nanoparticles, Materials Today Communications, 26, (2021), 102156 https://doi.org/10.1016/j.mtcomm.2021.102156
  34. Riyan Al Islam Reshad, Tawfiq Alam Jishan, Nafisa Nusrat Chowdhury, Chitosan and its broad applications: A brief review, Journal of Clinical and Experimental Investigations, 12, 4, (2021), em00779 https://doi.org/10.29333/jcei/11268
  35. Tianhong Dai, Masamitsu Tanaka, Ying-Ying Huang, Michael R. Hamblin, Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects, Expert Review of Anti-infective Therapy, 9, 7, (2011), 857-879 https://doi.org/10.1586/eri.11.59

Last update:

No citation recorded.

Last update: 2024-12-01 02:22:23

No citation recorded.