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Green Synthesis of Gold Nanoparticles Using Basella alba Leaf Extract and Their Antioxidant Activity

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya, Surabaya, Indonesia

Received: 28 Jun 2024; Revised: 14 Aug 2024; Accepted: 20 Aug 2024; Published: 31 Aug 2024.
Open Access Copyright 2024 Jurnal Kimia Sains dan Aplikasi under http://creativecommons.org/licenses/by-sa/4.0.

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Abstract

In this research, gold nanoparticles were synthesized using the green synthesis method with the bioreduction extract of Basella alba leaf infusion. This research aims to characterize gold nanoparticles synthesized using UV-Vis spectroscopy and TEM and assess their antioxidant activity, which is quantified by the IC50 value. The UV-Vis spectrophotometric characterization of the gold nanoparticles revealed an absorption peak at a maximum wavelength of 543 nm. TEM characterization indicated a particle diameter of 9.463 ± 2.273 nm. The antioxidant activity was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) reduction method with concentration variations of 2.5, 5, 10, and 20 ppm, resulting in reduction percentages of 40.6%, 44.3%, 57.4%, and 77.9%, respectively, and an IC50 value of 7.05 μg/mL, indicating very strong antioxidant activity. Based on these findings, it can be concluded that Basella alba leaf infusion extract is effective as a biological reducing agent in synthesizing gold nanoparticles, and the resulting nanoparticles show significant potential as antioxidants for reducing free radicals.

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Keywords: green synthesis; gold nanoparticles; Basella alba leaf extract; characterization; antioxidant

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  1. Matthew Huston, Melissa DeBella, Maria DiBella, Anisha Gupta, Green Synthesis of Nanomaterials, Nanomaterials, 11, 8, (2021), 2130 https://doi.org/10.3390/nano11082130
  2. S. Anu Mary Ealia, Manickam Puratchiveeran Saravanakumar, A review on the classification, characterisation, synthesis of nanoparticles and their application, IOP Conference Series: Materials Science and Engineering, 2017 https://doi.org/10.1088/1757-899X/263/3/032019
  3. Inès Hammami, Nadiyah M. Alabdallah, Amjad Al jomaa, Madiha kamoun, Gold nanoparticles: Synthesis properties and applications, Journal of King Saud University - Science, 33, 7, (2021), 101560 https://doi.org/10.1016/j.jksus.2021.101560
  4. Sapana Jadoun, Rizwan Arif, Nirmala Kumari Jangid, Rajesh Kumar Meena, Green synthesis of nanoparticles using plant extracts: a review, Environmental Chemistry Letters, 19, 1, (2021), 355-374 https://doi.org/10.1007/s10311-020-01074-x
  5. Mahliga Dwi Rezky Putri, Sabrina Dahlizar, Alfian Noviyanto, Sintesis, Kharakteristik, Penetrasi Kulit, dan Toksisitas Nanogold: A Systematic Review, Pharmaceutical Biomedical Sciences Journal, 2, 2, (2020), 65-78 https://doi.org/10.15408/pbsj.v2i2.18521
  6. Intan Nabilah Oktavia, Suyatno Sutoyo, Review Artikel: Sintesis Nanopartikel Perak Menggunakan Bioreduktor Ekstrak Tumbuhan Sebagai Bahan Antioksidan, UNESA Journal of Chemistry, 10, 1, (2021), 37-54 https://doi.org/10.26740/ujc.v10n1.p37-54
  7. Devina Ummul Agniya Ravana, Anggi Arumsari, Kajian Literatur Sintesis dan Karakterisasi Nanopartikel Emas Menggunakan Ekstrak Tanaman, Jurnal Riset Farmasi, 2, 1, (2022), 63-68 https://doi.org/10.29313/jrf.v2i1.848
  8. Ajay Chaurasiya, Rajesh Kumar Pal, Pradeep Kumar Verma, Avineet Katiyar, Narendra Kumar, An updated review on Malabar spinach (Basella alba and Basella rubra) and their importance, Journal of Pharmacognosy Phytochemistry, 10, 2, (2021), 1201-1207 https://doi.org/10.22271/phyto.2021.v10.i2p.13974
  9. Adegoke Gabriel Olaniran, Ojo Olaoluwa Ayodele, Phytochemical, Antioxidant and Antimicrobial Activities in the Leaf, Stem and Fruit Fractions of Basella Alba and Basella Rubra, Plant, 5, 5, (2017), 73-79 https://doi.org/10.11648/j.plant.20170505.11
  10. Bilkis Khanom, Umme Nahida, Shamima Sultana Shapla, Mst Shahina Akter, Hadia Farzana, Farhana Zaman, M. T. Islam, Phytochemical and pharmacological review on Basella alba L, Pharmacol Online, 1, Newsletter, (2019), 40-48
  11. Dia Novita Sari, Titik Taufikurohmah, Pengaruh Penambahan Nanogold Terhadap Aktivitas Antioksidan Ekstrak Gambir (Uncaria gambir Roxb.), UNESA Journal of Chemistry, 8, 1, (2019), 20-26
  12. Quinzheilla Putri Arnanda, Rina Fajri Nuwarda, Review Article: Penggunaan Radiofarmaka Teknesium-99m dari Senyawa Glutation dan Senyawa Flavonoid Sebagai Deteksi Dini Radikal Bebas Pemicu Kanker, Jurnal Farmaka, 17, 2, (2019), 236-243
  13. Abdullahi R. Abubakar, Mainul Haque, Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes, Journal of Pharmacy And Bioallied Sciences, 12, 1, (2020), 1-10 https://doi.org/10.4103/jpbs.JPBS_175_19
  14. Gusti Ayu Dewi Lestari, Kadek Duwi Cahyadi, Ni Ketut Esati, Biosintesis Nanopartikel Emas Menggunakan Ekstrak Air Buah Andaliman (Zanthoxylum acanthopodium DC.), Jurnal Harian Regional, 10, 1, 17-23
  15. Ana Elisa F. Oliveira, Arnaldo César Pereira, Mayra A. C. Resende, Lucas Franco Ferreira, Gold Nanoparticles: A Didactic Step-by-Step of the Synthesis Using the Turkevich Method, Mechanisms, and Characterizations, Analytica, 4, 2, (2023), 250-263 https://doi.org/10.3390/analytica4020020
  16. Babay Asih Suliasih, Setia Budi, Haliza Katas, Synthesis and application of gold nanoparticles as antioxidants, Pharmacia, 71, (2024), 1-19 https://doi.org/10.3897/pharmacia.71.e112322
  17. Mohamed Habib Oueslati, Lotfi Ben Tahar, Abdel Halim Harrath, Catalytic, antioxidant and anticancer activities of gold nanoparticles synthesized by kaempferol glucoside from Lotus leguminosae, Arabian Journal of Chemistry, 13, 1, (2020), 3112-3122 https://doi.org/10.1016/j.arabjc.2018.09.003
  18. Ryan D. Mellor, Ijeoma F. Uchegbu, Ultrasmall-in-Nano: Why Size Matters, Nanomaterials, 12, 14, (2022), 2476 https://doi.org/10.3390/nano12142476
  19. Filza Qurrota ‘Aini, Titik Taufikurohmah, The Effect of Nanogold-Nanosilver Injection on Increasing the Immunity of Community Affected by Covid-19, International Journal of Current Science Research and Review, 5, 4, 1116-1125 https://doi.org/10.47191/ijcsrr/V5-i4-34
  20. Poornima Budime Santhosh, Julia Genova, Hassan Chamati, Green Synthesis of Gold Nanoparticles: An Eco-Friendly Approach, Chemistry, 4, 2, (2022), 345-369 https://doi.org/10.3390/chemistry4020026
  21. Kehinde Oluseun Sodeinde, Enock Olugbenga Dare, Neerish Revaprasadu, Biosynthesis, characterization and material applications of gold, silver, and palladium nanoparticles using aqueous extract of Basella alba leaves (Basellaceae), The Pacific Journal of Science Technology, 17, 1, (2016), 170-176
  22. Egista Istioka Fazrin, Annisa Ilma Naviardianti, Santhy Wyantuti, Shabarni Gaffar, Yeni Wahyuni Hartati, Review: Sintesis dan Karakterisasi Nanopartikel Emas (AuNP) Serta Konjugasi AuNP Dengan DNA Dalam Aplikasi Biosensor Elektrokimia, PENDIPA Journal of Science Education, 4, 2, (2020), 21-39 https://doi.org/10.33369/pendipa.4.2.21-39

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