Sepsis dan Tata Laksana Berdasar Guideline Terbaru
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Istilah Sepsis menurut konsensus terbaru adalah keadaan disfungsi organ yang mengancam jiwa yang disebabkan karena disregulasi respon tubuh terhadap infeksi. Penggunaan kriteria SIRS untuk mengidentifikasi sepsis dianggap tidak membantu lagi. Kriteria SIRS tidak menggambarkan adanya respon disregulasi yang mengancam jiwa. Disfungsi organ didiagnosis apabila peningkatan skor SOFA ≥ 2. Dan istilah sepsis berat sudah tidak digunakan. Septik syok didefinisikan sebagai keadaan sepsis dimana abnormalitas sirkulasi dan metabolik yang terjadi dapat menyebabkan kematian secara signifikan. Dalam protokol yang dikeluarkan pada tahun 2016, target resusitasi EGDT dihilangkan, dan merekomendasikan terapi cairan kristaloid minimal sebesar 30 ml/kgBB dalam 3 jam atau kurang.
Keywords
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