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Seksio Sesarea pada Wanita G2P1A0 Hamil Aterm dengan Confirmed COVID-19 Disertai Diabetes Mellitus Dalam Terapi Insulin dan HIV Positif

1Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro/ RSUP Dr. Kariadi, Semarang, Indonesia

2Departemen Anestesiologi dan Terapi Intensif, Fakultas Kedokteran, Universitas Diponegoro/ RSUP Dr. Kariadi Semarang, Indonesia

Published: 30 Nov 2022.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)

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Abstract

Latar Belakang: Coronavirus disease 2019 (COVID-19) adalah penyakit sistem pernapasan akut yang disebabkan oleh virus corona jenis baru (SARS-CoV-2) yang pertama kali ditemukan pada bulan Desember 2019 di Wuhan, Provinsi Hubei, China. Beberapa penyakit salah satunya diabetes mellitus, menjadi penyakit predisposisi perjalanan penyakit yang berat dan meningkatkan risiko kematian akibat COVID-19.  Penderita COVID-19, terlebih yang memiliki predisposisi penyakit lain seperti diabetes mellitus dan HIV, menjadi hal yang perlu diperhatikan dalam pengelolaan perioperatif. Laporan kasus ini akan membahas teknik anestesi yang dipilih pada pasien ini, yang mana pasien dalam kondisi hamil, dengan COVID-19, diabetes mellitus, dan HIV positif.

Kasus: Kami melaporkan sebuah kasus, seorang wanita 31 tahun dengan diagnosis G2P1A0 hamil aterm dirujuk ke RSUP Dr. Kariadi dengan HIV positif diabetes mellitus on insulin, bekas seksio sesarea, penderita dalam pengawasan (PDP) COVID-19. Penderita memiliki riwayat diabetes mellitus dengan insulin sejak 6 tahun lalu dan dinyatakan positif HIV sejak tahun 2019. Penderita memiliki keluhan batuk kering sejak 1 bulan yang lalu. Pada pemeriksaan fisik didapatkan keadaan umum penderita tampak baik dengan kesadaran composmentis, tanda vital dalam batas normal. Swab antigen COVID-19 dinyatakan positif. Pada pemeriksaan laboratorium didapatkan keadaan anemia ringan dan hiponatremia. Penderita menjalani operasi seksio sesarea dengan anestesi spinal.

Pembahasan: Sebelum operasi, selama operasi dan pascaoperasi seksio sesarea, hemodinamik penderita dalam keadaan stabil, hasil lab gula darah didapatkan hasil normal.  Penderita kemudian dirawat di ruangan dengan perawatan isolasi COVID-19.

Kesimpulan: Anestesi regional merupakan pilihan untuk penderita dengan COVID-19 bila memungkinkan. Teknik anestesi regional yang tepat dapat menjaga fungsi pernapasan dan menghindari aerosolisasi untuk mencegah penularan virus COVID-19 dengan tetap memperhatikan level Alat Pelindung Diri dan penggunaan ruangan bertekanan negatif. Obat-obat anestesi umum dapat berbahaya bila berinteraksi dengan obat HIV, maka dari itu, anestesi regional lebih dipilih.

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Keywords: anestesi spinal; DM dengan insulin; HIV; kehamilan pada COVID-19; seksio sesarea

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  1. Rasmussen SA, Smulian JC, et al. Coronavirus Disease 2019 (COVID-19) and Pregnancy: What Obstetricians Need to Know. American Journal of Obstetric and Gynecology. 2020;1-13
  2. Hoffmann M, Kleine-Weber H, Schroeder S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181(2):271-280
  3. Sungnak W, Huang N, Bécavin C, et al; HCA Lung Biological Network. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020;26(5):681-687
  4. Zou X, Chen K, Zou J, Han P, Hao J, Han Z. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Front Med. 2020;14(2):185-192
  5. Xu Z, Shi L, Wang Y, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020;8(4):420-422
  6. Budiarti E, Tamtomo DG, Adriani RB. Path analysis on the biopsychosocial determinants of type 2 diabetes mellitus and depression at Dr. Moewardi Hospital, Surakarta. J Epidemiol Public Health. 2017;(01):1–14
  7. Jeong IK, Yoon KH, Lee MK. Diabetes and COVID-19: Global and regional perspectives. Diabetes Research. 2020
  8. Kementrian Kesehatan RI. Hasil Utama Riskesdas. 2018. Jakarta; 66-70
  9. Siti Chasnak, S, 2000, Perioperatif Penderita Diabetes Mellitus dalam Buku Naskah Lengkap Kongres Nasional III Ikatan Dokter Spesialis Anestesiologi Indonesia, Jakarta; hal. 219-228
  10. Fauci AS, Folkers GK, Lane HC. Human Immunodeficiency Virus Disease: AIDS and Related Disorders. In: Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine, 20e. New York, NY: McGraw-Hill Education; 2018
  11. Direktorat Jenderal Pencegahan Dan Pengendalian Penyakit. Laporan Perkembangan HIV/AIDS & Penyakit Infeksi Menular Seksual (PIMS) Triwulan I Tahun 2021. Jakarta; 2021
  12. World Health Organization. Mother-to-child transmission of HIV. Geneva. 2015
  13. Marhl M,Grubelnik V, Magdic M, Markovic R. Diabetes and metabolic syndrome as risk factors for COVID-19. Clinical Research and Reviews. 2020;14(4): 671–677
  14. Peric S, Stulnig TM. Diabetes and COVID-19: Disease Management People. Wiener Klinische Wochenschrift. Springer Medizin, 2020;132(13-14): 356–361
  15. Pedrosa MS, Neves NF. COVID-19 and diabetes: What should we expect?. Journal of Diabetes Science and Technology. 2020:1133–1134
  16. Worldometer. Coronavirus Cases Update. [Internet] Available at: < https://www.worldometers.info/coronavirus/>
  17. Liu H, Wang LL, et al. Why Are Pregnant Women Susceptible to COVIS-19? An Immunilogical ViewPoint. Jorunal of Reproductive Immunology. 2020; 139: 1-4
  18. Zhao X, Jiang Y, et al. Analysis of the Susceptibility to COVID-19 in Pregnancy and Recommendation on Potential Drug Screening. European Journal of Clinical Micobiology & Infectious Disease. 2020: 1-12
  19. Nile SH, Nile A, Kai G, et al. COVID-19: Pathogenesis, Cytokine Storm, and Therapeutic Potntial of Interferons. Elseveir. 2020; 1-5
  20. Chen H, Guo J, et al. Clinical Characteristics and Intrauterine Vertical Transmission Potential of COVID-19 Infection in Nine Pregnant Women: A Retrospective Review of Medical Records. Elseveir. 2020; 395: 809-815
  21. Zhu H, Wang L, et al. Clinical Analysis of 10 Neonatus Born to Mothers with 2019-nCoV Pneumonia. Translational Pediatrics. 2020; 9(1): 51-60
  22. Perhimpunan Dokter Anestesiologi dan Terapi Intensif Indonesia. Manajemen Perioperatif Pasien COVID-19. Edisi 1. 2020
  23. Breslin N, Baptiste C, et al. Coronavirus Disease 2019 Infection Among Asymptomatic and Symptomatic Pregnant WOmenL Two Weeks of Confirmed Presentation to an Affliated Pair of New York City Hospital. American Journal of Obstetric and Gynecology. 2020; 1-7
  24. Wang W, XU Y, et al. Detection of SARS-CoV-2 in Different Types Clinical Specimens. JAMA. 2020; 1-2
  25. Perkumpulan Obstetri dan Gimekologi Indonesia. Rekoemndasi Penanganan Infeksi Virus Corona (COVID-19) pada Maternal. 2020
  26. Boelig RC, Manuck T, et al. Labor and Delivery Guidance for COVID-19. American Journal of Obstetric and Gynecology. 2020; 1-10
  27. Marta L, Anna G, et al. COVID-19 in Pregnancy: A Clinical Management Protocol and Consideration for Practice. Research Gate. 2020; 1-26
  28. Ashokka B, Loh MH, et al. Care of the Pregnant Woman with Coronavirus Disease 2019 in Labor and Delivery: Anesthesia, Emergency Cesarean Delivery, Differential Diagnosis in the Acutely Ill Parturient, Care of the Newborn, and Protection of the Health Care Personnel. American Journal of Obstetric and Gynecology. 2020; 1-12
  29. Chen R, Zhang Y, et al. Safety and Efficay of Different Anesthetic Regimens for Parturients with COVID-19 Undergoing Cesarean Delivery: A Case Series of 17 Patients. Canadian Journal of Anasthesia. 2020; 67: 655-663
  30. Penfield CA, Brubaker SG, et al. Detection of SARS-CoV-2 in Placental and Fetal Membrane Samples. American Journal of Obstetric and Gynecology. 2020; 1-9
  31. Bampoe S, Odor PM, Lucas DN. Novel Coronavirus SARS-CoV-2 and COVID-19, Practice Recommendations for Obstetric Anaesthesia What We Have Learned Thus Far. Intermational Journal of Obstetric Anesthesia. 2020;1-22

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