DOI: https://doi.org/10.14710/jai.v0i0.68607

COMPARISON OF THE EFFECTS OF FENTANYL 0.7 MCG/KGBB WITH KETAMINE 0.2 MG/KGBB ON THE QUALITY OF RECOVERY POST GENERAL ANESTHESIA WITH QOR-40 SCORING IN LAPARATOMY SURGERY

1Master of Clinical Medicine/ Anesthesiology and Intensive Therapy Study Program, Faculty of Medicine, Universitas Sumatera Utara, Adam Malik General Hospital, Medan, Indonesia;, Indonesia

2Study Program Of Anesthesiology and Intensive Therapy,Faculty of Medicine,Universitas Sumatera Utara, Adam Malik General Hospital, Medan, Indonesia;, Indonesia

Received: 2 Dec 2024; Revised: 18 Jun 2025; Accepted: 4 Jul 2025; Available online: 7 Jul 2025.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Citation Format:
Abstract

COMPARISON OF THE EFFECTS OF FENTANYL 0.7 MCG/KGBB WITH KETAMINE 0.2 MG/KGBB ON THE QUALITY OF RECOVERY POST GENERAL ANESTHESIA WITH QOR-40 SCORING IN LAPARATOMY SURGERY

Imam Syahputra 1, Sinta Irina2, Bastian Lubis 2

 

1Master of Clinical Medicine/ Anesthesiology and Intensive Therapy Study Program, Faculty of Medicine, Universitas Sumatera Utara, Adam Malik General Hospital, Medan, Indonesia;

2Study Program Of Anesthesiology and Intensive Therapy,Faculty of Medicine,Universitas Sumatera Utara, Adam Malik General Hospital, Medan, Indonesia;

 

 Abstract

Background: Evaluation of post-general anesthesia recovery is crucial in assessing the final outcome of anesthesia procedures. Quality of Recovery-40 (QoR-40), a questionnaire instrument specifically assesses the quality of post-general anesthesia recovery comprehensively. Researchers are interested in comparing two types of drugs, namely Fentanyl and ketamine, on the quality of post-general anesthesia recovery.

Methods: This study is a comparative categorical analytical experimental method study with a double-blind randomized clinical controlled trial (RCT) design. Analyzing the comparative effects of fentanyl and ketamine on the quality of post-general anesthesia recovery in laparotomy surgery patients assessed by QoR-40 at General Hospital Haji Medan. Subject selection technique using consecutive sampling method where 42 subjects are needed. Bivariate analysis for numeric variables using the Independent T-test if the data is normally distributed, or the Mann Whitney U test if the data is not normally distributed. The results of the analysis are said to be significant if p <0.05, with a confidence level of 95%.

Results: The results of the study showed that the total QoR-40 score for fentanyl use had an average of 172.4762 + 3.81601, while in the group using ketamine, the average score was 174.7619 + 3.37498, which had a significant difference between the fentanyl group and the ketamine group with p <0.05.

Conclusion: Ketamine has better effectiveness than fentanyl in terms of comfort on the QoR-40 questionnaire, as evidenced by the comfort value for ketamine being statistically higher than fentanyl.

 

Keywords: Ketamine, Fentanyl, QoR-40

Note: This article has supplementary file(s).

Fulltext |  Research Instrument
Untitled
Subject
Type Research Instrument
  Download (639KB)    Indexing metadata
 Research Instrument
Untitled
Subject
Type Research Instrument
  Download (263KB)    Indexing metadata
 Research Instrument
Untitled
Subject
Type Research Instrument
  Download (46KB)    Indexing metadata
 common.other
lampiran Qor40
Subject
Type Other
  Download (1MB)    Indexing metadata
 common.other
lampiran Qor40
Subject
Type Other
  Download (1MB)    Indexing metadata

Article Metrics:

Article Info
Section: Original Articles
Language : EN
Recent articles
COMPARISON OF EFFECTIVENESS OF GIVING COMBINATION OF DEXMEDETOMIDINE 5µg FENTANYL 25µg INTRATECHAL AND FENTANYL 25µg INTRATECHAL AS ADJUVANT TO BUPIVACAINE IN SPINAL ANESTHESIA AT HAJI ADAM MALIK CENTRAL GENERAL HOSPITAL MEDAN THE EFFECT OF MIDAZOLAM SEDATION ON AGITATION INCIDENCE IN POST-OPERATIVE PATIENTS WHO ARE INTUBATED IN THE ICU OF HOSPITAL HAJI ADAM MALIK MEDAN COMPARISON OF THE EFFECTS OF FENTANYL 0.7 MCG/KGBB WITH KETAMINE 0.2 MG/KGBB ON THE QUALITY OF RECOVERY POST GENERAL ANESTHESIA WITH QOR-40 SCORING IN LAPARATOMY SURGERY Rare Case of Neurosurgical Anesthesia in a Patient with Recidive Cystic Tumor and Cerebral Edema Re-craniotomy tumor excision and decompression: Case Report NUTRITION THERAPY IN POST-HARTMANN PROCEDURE PATIENTS IN THE INTENSIVE CARE UNIT Successful of High Risk Pulseless-Balloon Aortic Valvuloplasty Procedure in Uncorrected Pulmonary Atresia with Severe Congenital Aortic Stenosis and Low Left Ventricular Function Malignant Hyperthermia Combination of Vitamin D and Vitamin E Against Bacterial Infections More recent articles
Most cited articles
Midazolam Intravena Dosis Rendah Tidak Mempengaruhi Nitric Oxide Intraperitoneal Mencit Balb/C Yang Terpapar Lipopolisakarida Patofisiologi Penyakit Jantung Koroner More cited articles
  1. Widayati DS, Firdaus AD, Handian FI. The Relationship Between Level of Knowledge About Early Mobilization with Pain Intensity of Post Laparotomy Patients. The Journal of Palembang Nursing Studies. 2022 May 5;1(2):28-33
  2. Toro MM, John S, Faruqui AR. Pattern of use of analgesics in post-operative pain management in adults undergoing laparotomy surgery: a prospective observational study. International Surgery Journal. 2018 Jan 25;5(2):662-7
  3. Hontoir S, Saxena S, Gatto P, Khalife M, Ben Aziz AM, Paesmans M, et al. Opioid-free anesthesia: what about patient comfort? A prospective, randomized, controlled trial. Acta Anaesthesiol Belg. 2016;67(4):183–90
  4. HarijantoA E, Wijaya AA, Handayani D. Uji kesahihan dan keandalan qor-40 versi indonesia sebagai instrumen untuk menilai kualitas pemulihan Paska-anestesia umum. Majalah Anestesia dan Critical Care. 2016;34(2)
  5. Pratama A, Pradian E, Erlangga ME. Perbandingan Efek Fentanil dengan Ketamin terhadap Skor Pemulihan Paskaanestesi Umum Diukur dengan QoR-40 serta Perubahan Tekanan Darah dan Nadi pada Operasi Odontektomi. jap. 2020;8(3):149–57
  6. Zhang J, Wang F, Dang J, Zheng H, Ren B, Liu C, et al. Effect of Intraoperative Infusion of Esketamine on Quality of Postoperative Recovery in Patients Undergoing Laparoscopic Bariatric Surgery: A Randomized Controlled Trial. Pain Ther. 2023 Aug;12(4):979-992
  7. Krishnasamy Yuvaraj A, Gayathri B, Balasubramanian N, Mirunalini G. Patient Comfort During Postop Period in Breast Cancer Surgeries: A Randomized Controlled Trial Comparing Opioid and Opioid-Free Anesthesia. Cureus. 2023 Jan 17;15(1):e33871
  8. Mulier JP, Wouters R, Dillemans B, Dekock M, A randomized controlled, double-blind trial evaluating the effect of opioid-free versus opioid general anaesthesia on postoperative pain and discomfort measured by the QoR-40. J Clin Anesth Pain Med. 2018, 6:2
  9. Ibrahim M, Elnabtity AM, Hegab A, Alnujaidi OA, El Sanea O. Combined opioid free and loco-regional anaesthesia enhances the quality of recovery in sleeve gastrectomy done under ERAS protocol: a randomized controlled trial. BMC Anesthesiol. 2022 Jan 21;22(1):29
  10. Ulbing S, Infanger L, Fleischmann E, Prager G, Hamp T. The Performance of Opioid-Free Anesthesia for Bariatric Surgery in Clinical Practice. Obes Surg. 2023 Jun;33(6):1687-1693.
  11. Efe Mercanoglu E, Girgin Kelebek N, Turker G, Aksu H, Ozgur M, Karakuzu Z, et al. Comparison of the Effect of Ketamine and Dexmedetomidine Combined with Total Intravenous Anesthesia in Laparoscopic Cholecystectomy Procedures: A Prospective Randomized Controlled Study. Int J Clin Pract. 2022 Jul 21;2022:1878705
  12. Hung KC, Kao CL, Ho CN, Hsing CH, Chang YJ, Wang LK, et al. The impact of perioperative ketamine or esketamine on the subjective quality of recovery after surgery: a meta-analysis of randomised controlled trials. Br J Anaesth. 2024 Jun;132(6):1293-1303
  13. Tochie JN, Bengono Bengono RS, Metogo JM, Ndikontar R, Ngouatna S, Ntock FN, et al. The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study. BMC Anesthesiol. 2022 Oct 24;22(1):325.

Last update:

No citation recorded.

Last update: 2025-07-07 09:46:10

No citation recorded.