skip to main content

Impact of Alkaline Immersion Time on Nano-Hydroxyapatite Synthesis from Broiler Eggshells with Electrochemical Method Using Constant Direct Current (CDC)

Department of Chemical Engineering, Faculty of Engineering, Diponegoro University, Semarang, Indonesia

Received: 30 Oct 2023; Revised: 19 Dec 2023; Accepted: 21 Dec 2023; Published: 25 Dec 2023.
Open Access Copyright 2023 Jurnal Kimia Sains dan Aplikasi under http://creativecommons.org/licenses/by-sa/4.0.

Citation Format:
Cover Image
Abstract
Calcium phosphate is widely used in biomaterials, especially as a bone substitute. One of the calcium phosphate compounds that is widely used is hydroxyapatite. In biomedical applications, nano-sized hydroxyapatite particles have better bioactivity than coarse crystals. Hydroxyapatite can be synthesized from various sources of calcium and phosphate. Broiler eggshells were chosen as a source of calcium in this study because they have a relatively high calcium content. The method used in the synthesis of nano-hydroxyapatite in this research is the electrochemical method. This research aims to examine the effect of varying NaOH immersion time on the size and structure of calcium phosphate particles produced using an electrochemical method made from chicken egg shells. The synthesis of nano-hydroxyapatite from chicken egg shells was carried out in 4 stages: material preparation, electrolysis, precipitate immersion, and characterization. Nanometer-sized particles can be acquired through an immersion process lasting at least four hours, and it is observed that the longer the duration of immersion, the greater the resemblance of the resulting structure to hydroxyapatite.
Fulltext View|Download
Keywords: hydroxyapatite; electrochemical; broiler eggshells; immersion time; NaOH
Funding: Diponegoro University

Article Metrics:

  1. Shih-Ching Wu, Hsueh-Chuan Hsu, Hsueh-Fang Wang, Shu-Ping Liou, Wen-Fu Ho, Synthesis and Characterization of Nano-Hydroxyapatite Obtained from Eggshell via the Hydrothermal Process and the Precipitation Method, Molecules, 28, 13, (2023), 4926 https://doi.org/10.3390/molecules28134926
  2. Rebaz Obaid Kareem, Omer Kaygili, Tankut Ates, Niyazi Bulut, Suleyman Koytepe, Ali Kuruçay, Filiz Ercan, Ismail Ercan, Experimental and theoretical characterization of Bi-based hydroxyapatites doped with Ce, Ceramics International, 48, 22, (2022), 33440-33454 https://doi.org/10.1016/j.ceramint.2022.07.287
  3. Dewantoro Dewantoro, Margareta Novian Cahyanti, Sri Hartini, Effect of Phosphate Addition and Exposure of Micro Waves on Comparatives Ca/F in Gipsum Waste: Preliminary Study of Hydroxyappatite Synthesis (HAp) from Ceramics Gypsum Industry Waste, Jurnal Kimia Sains dan Aplikasi, 21, 4, (2018), 218-223 https://doi.org/10.14710/jksa.21.4.218-223
  4. Nur Akbar, Asril Pramutadi Andi Mustari, Atiek Rostika Noviyanti, New Chemicals and Routes for the Preparation of Gelatin/HA Composites using the Wet Precipitation Method, Jurnal Kimia Sains dan Aplikasi, 23, 2, (2020), 46-50 https://doi.org/10.14710/jksa.23.2.46-50
  5. Himanshu Khandelwal, Satya Prakash, Synthesis and characterization of hydroxyapatite powder by eggshell, Journal of Minerals and Materials Characterization and Engineering, 4, 2, (2016), 119-126 http://dx.doi.org/10.4236/jmmce.2016.42011
  6. Fatih İsen, Omer Kaygili, Niyazi Bulut, Tankut Ates, Fatih Osmanlıoğlu, Serhat Keser, Beyhan Tatar, İmren Özcan, Burhan Ates, Filiz Ercan, Experimental and theoretical characterization of Dy-doped hydroxyapatites, Journal of the Australian Ceramic Society, 59, (2023), 849–864 https://doi.org/10.1007/s41779-023-00878-8
  7. Sergey V. Dorozhkin, Bioceramics of calcium orthophosphates, Biomaterials, 31, 7, (2010), 1465-1485 https://doi.org/10.1016/j.biomaterials.2009.11.050
  8. Yoshiki Oshida, in, Momentum Press New York [New York] (222 East 46th Street, New York, NY 10017), New York [New York] (222 East 46th Street, New York, NY 10017), 2015,
  9. Saranya R., Aruna Devi B., Meenakshi Sundaram N., Preparation of ciprofloxacin-loaded oyster shell derived hydroxyapatite composite film for biomedical applications, Journal of the Australian Ceramic Society, 59, (2023), 621-632 https://doi.org/10.1007/s41779-023-00861-3
  10. M. Sari, Y. Yusuf, Synthesis and characterization of hydroxyapatite based on green mussel shells (perna viridis) with the variation of stirring time using the precipitation method, IOP Conference Series: Materials Science and Engineering, 432, (2018), 012046 https://doi.org/10.1088/1757-899X/432/1/012046
  11. Jamiu K. Odusote, Y. Danyuo, Abdulazeez D. Baruwa, Akeem A. Azeez, Synthesis and characterization of hydroxyapatite from bovine bone for production of dental implants, Journal of Applied Biomaterials & Functional Materials, 17, 2, (2019), https://doi.org/10.1177/2280800019836829
  12. Renata Neves Granito, Ana Claudia Renno, Hirochi Yamamura, Matheus Cruz de Almeida, Pedro Luiz Menin Ruiz, Daniel Araki Ribeiro, Hydroxyapatite from Fish for Bone Tissue Engineering: A Promising Approach, International Journal of Molecular and Cellular Medicine, 7, 2, (2018), 80-90 https://doi.org/10.22088/ijmcm.Bums.7.2.80
  13. Huda S. Alhasan, Nadiyah Alahmadi, Suhad A. Yasin, Mohammed Y. Khalaf, Gomaa A. M. Ali, Low-Cost and Eco-Friendly Hydroxyapatite Nanoparticles Derived from Eggshell Waste for Cephalexin Removal, Separations, 9, 1, (2022), 10 https://doi.org/10.3390/separations9010010
  14. N. A. S. Mohd Pu'ad, J. Alipal, H. Z. Abdullah, M. I. Idris, T. C. Lee, Synthesis of eggshell derived hydroxyapatite via chemical precipitation and calcination method, Materials Today: Proceedings, 42, (2021), 172-177 https://doi.org/10.1016/j.matpr.2020.11.276
  15. Parisa Taghipour, Farhad Zolfagharpour, Hamideh Daneshvar, Synthesis of hydroxyapatite through solid-state reaction method and study of its thermoluminesence dosimetric properties against gamma rays, Radiation Physics and Engineering, 3, 2, (2022), 7-10 https://doi.org/10.22034/rpe.2022.335334.1062
  16. M. S. AlHammad, Nanostructure hydroxyapatite based ceramics by sol gel method, Journal of Alloys and Compounds, 661, (2016), 251-256 https://doi.org/10.1016/j.jallcom.2015.11.045
  17. V. Collins Arun Prakash, I. Venda, V. Thamizharasi, Synthesis and characterization of surfactant assisted hydroxyapatite powder using microemulsion method, Materials Today: Proceedings, 51, (2022), 1788-1792 https://doi.org/10.1016/j.matpr.2021.05.059
  18. Jung Sang Cho, Yun Chan Kang, Nano-sized hydroxyapatite powders prepared by flame spray pyrolysis, Journal of Alloys and Compounds, 464, 1, (2008), 282-287 https://doi.org/10.1016/j.jallcom.2007.09.092
  19. Adrian Nur, Alifah Rahmawati, Noor Izzati Ilmi, Samsudin Affandi, Arief Widjaja, Electrochemical synthesis of nanosized hydroxyapatite by pulsed direct current method, AIP Conference Proceedings, 1586, (2014), 86-91 https://doi.org/10.1063/1.4866736
  20. Shahid Hussain, Kazi Sabiruddin, Synthesis of eggshell based hydroxyapatite using hydrothermal method, IOP Conference Series: Materials Science and Engineering, 1189, (2021), 012024 https://doi.org/10.1088/1757-899X/1189/1/012024
  21. Adrian Nur, Heru Setyawan, Arief Widjaja, I Wuled Lenggoro, Electrochemical processes for the formation of hydroxyapatite powders, Bulletin of Chemical Reaction Engineering & Catalysis, 9, 3, (2014), 168-175 https://doi.org/10.9767/bcrec.9.3.6686.168-175
  22. Fauziatul Fajaroh, Heru Setyawan, W. Widiyastuti, Sugeng Winardi, Synthesis of magnetite nanoparticles by surfactant-free electrochemical method in an aqueous system, Advanced Powder Technology, 23, 3, (2012), 328-333 https://doi.org/10.1016/j.apt.2011.04.007
  23. M. S. Djošić, V. B. Mišković-Stanković, Z. M. Kačarević-Popović, B. M. Jokić, N. Bibić, M. Mitrić, S. K. Milonjić, R. Jančić-Heinemann, J. Stojanović, Electrochemical synthesis of nanosized monetite powder and its electrophoretic deposition on titanium, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 341, 1, (2009), 110-117 https://doi.org/10.1016/j.colsurfa.2009.03.046
  24. Asep Muhamad Samsudin, Hargono, Kristinah Haryani, Hantoro Satriadi, Hana Nikma Ulya, M. Akhsanil Auladi, Effect of pH on Nano-Hydroxyapatite Synthesis from Chicken Eggshell Prepared by Electrochemical Method, Advanced Science Letters, 23, 6, (2017), 5733-5735 https://doi.org/10.1166/asl.2017.8816
  25. Asep Muhamad Samsudin, Norman Iskandar, Didik Setiyo Widodo, Hana Nikma Ulya, M. Akhsanil Auladi, Effect of Current Density on Nano-Hydroxyapatite Synthesis from Chicken Eggshell Using Electrochemical Method with Constant Direct Current (CDC), Advanced Science Letters, 23, 6, (2017), 5736-5738 https://doi.org/10.1166/asl.2017.8817
  26. Idris Abdulrahman, Hamzat Ibiyeye Tijani, Bashir Abubakar Mohammed, Haruna Saidu, Hindatu Yusuf, Mohammed Ndejiko Jibrin, Sulaiman Mohammed, From Garbage to Biomaterials: An Overview on Egg Shell Based Hydroxyapatite, Journal of Materials, 2014, (2014), 802467 https://doi.org/10.1155/2014/802467
  27. Setyanto Tri Wahyudi, Setia Utami Dewi, Ajeng Anggraeni, Kiagus Dahlan, Akhmaloka, Muhammad Ali Zulfikar, Rukman Hertadi, Simple and easy method to synthesize chicken eggshell based hydroxyapatite, Advanced materials research, 896, (2014), 276-279 https://doi.org/10.4028/www.scientific.net/AMR.896.276
  28. Mohammad Zulhasif Ahmad Khiri, Khamirul Amin Matori, Norhazlin Zainuddin, Che Azurahanim Che Abdullah, Zarifah Nadakkavil Alassan, Nur Fadilah Baharuddin, Mohd Hafiz Mohd Zaid, The usability of ark clam shell (Anadara granosa) as calcium precursor to produce hydroxyapatite nanoparticle via wet chemical precipitate method in various sintering temperature, SpringerPlus, 5, (2016), 1206 https://doi.org/10.1186/s40064-016-2824-y
  29. Nadia Razali, Nurriswin Jumadi, Adlin Yasmin Jalani, Nurhanim Zulaikha Kamarulzaman, Khairul Faizal Pa’ee, Thermal decomposition of calcium carbonate in chicken eggshells: study on temperature and contact time, The Malaysian Journal of Analytical Sciences, 26, 2, (2022), 347-359
  30. Duygu Ağaoğulları, Özge Balcı, M. Lütfi Öveçoğlu, İsmail Duman, Preparation of LaB6 Powders via Calciothermic Reduction using Mechanochemistry and Acid Leaching, KONA Powder and Particle Journal, 33, (2016), 203-218 https://doi.org/10.14356/kona.2016001
  31. Alex Gu, Canis Li, Jamin Xie, Daisy Zeng, Kingshuk Daschowdhury, Leon Yee, Yitian Li, Austin Chiang, Emeka Okekeocha, Effects of microconvection on bubble displacement during water electrolysis under microgravity, Journal of Emerging Investigators, 6, (2023), 1-6
  32. M. H. Prado Da Silva, J. H. C. Lima, G. A. Soares, C. N. Elias, M. C. de Andrade, S. M. Best, I. R. Gibson, Transformation of monetite to hydroxyapatite in bioactive coatings on titanium, Surface and Coatings Technology, 137, 2, (2001), 270-276 https://doi.org/10.1016/S0257-8972(00)01125-7
  33. Rebaz Obaid Kareem, Niyazi Bulut, Omer Kaygili, Hydroxyapatite Biomaterials: A Comprehensive Review of their Properties, Structures, Medical Applications, and Fabrication Methods, Journal of Chemical Reviews, 6, 1, (2024), 1-26 https://doi.org/10.48309/jcr.2024.415051.1253
  34. M. S. Djošić, V. B. Mišković-Stanković, S. Milonjić, Z. M. Kačarević-Popović, N. Bibić, J. Stojanović, Electrochemical synthesis and characterization of hydroxyapatite powders, Materials Chemistry and Physics, 111, 1, (2008), 137-142 https://doi.org/10.1016/j.matchemphys.2008.03.045
  35. Adrian Nur, Heru Setyawan, An Experimental and Theoretical Investigation of the Formation of Hydroxyapatite Particles Prepared by an Electrochemical Method, Journal of Chemical Engineering of Japan, 49, 2, (2016), 144-151 https://doi.org/10.1252/jcej.15we130
  36. K. Ioku, S. Yamauchi, H. Fujimori, S. Goto, M. Yoshimura, Hydrothermal preparation of fibrous apatite and apatite sheet, Solid State Ionics, 151, 1, (2002), 147-150 https://doi.org/10.1016/S0167-2738(02)00593-3
  37. Sohrab Nasiri, Marzieh Rabiei, Arvydas Palevicius, Giedrius Janusas, Andrius Vilkauskas, Venkatramaiah Nutalapati, Ahmad Monshi, Modified Scherrer equation to calculate crystal size by XRD with high accuracy, examples Fe2O3, TiO2 and V2O5, Nano Trends, 3, (2023), 100015 https://doi.org/10.1016/j.nwnano.2023.100015

Last update:

No citation recorded.

Last update: 2024-06-17 06:26:45

No citation recorded.