Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University, Indonesia
BibTex Citation Data :
@article{JKSA18556, author = {Enny Fachriyah and Dewi Kusrini and Pratama Wibawa}, title = {Improvement of Bioactivity with Nanoparticle Fabrication: Cytotoxic Test of Ethanol, N-Hexane and Ethyl Acetate Extract from Red Galangal Rhizome (Alpinia purpurata (Vieill.) K. Schum) in Bulk and Nanoparticle size using BSLT Method}, journal = {Jurnal Kimia Sains dan Aplikasi}, volume = {21}, number = {1}, year = {2018}, keywords = {Red galangal; nanoparticles; maceration; ethanol; n-hexane; ethyl acetate; cytotoxic activity; BSLT; LC50}, abstract = {Some of the secondary metabolites present in red algae are terpenoids, quinones, flavonoids, alkaloids, essential oils, diarylheptanoids, steroids, cardioglycosides, oils and fats, tannins, carbohydrates. Activity of rhizomes, leaves and flowers red leaf is as antimicrobial, anti-fungal, anti-oxidants, anti-tumor, anti-cancer and vasodilator. One way to improve the physical, chemical and bioactivity properties of natural compounds was to make them into nanoparticles. In this study, the isolation of bioactive compounds contained in red laos rhizome by maceration method using ethanol solvent was done, then partitioned with n-hexane and ethyl acetate. The extracts thus obtained are fabricated into nanoparticles. Extracts in bulk and nanoparticles were then tested for cytotoxic activity using BSLT method. Results of analysis with PSA showed that ethanol extract had size 410,8 nm, n-hexane extract 220,7 nm and ethyl acetate extract 208,3 nm. The results of cytotoxic tests showed that nanoparticle size increased cytotoxic activity. Ethyl acetate extract was most active compared to ethanol and n-hexane extracts with LC 50 values of 17.919; 84,956; 166,526 ppm. Whereas the nanoparticle size was respectively 10,491; 74,072 and 84,197 ppm. Cytotoxic activity increases with nanoparticle fabrication. }, issn = {2597-9914}, pages = {39--43} doi = {10.14710/jksa.21.1.39-43}, url = {https://ejournal.undip.ac.id/index.php/ksa/article/view/18556} }
Refworks Citation Data :
Article Metrics:
Last update:
Isolation of Flavonoid Compounds from Amyl Alcohol Fraction of Golek Mango Leaf (Mangifera indica L cv. Golek)
Phytochemical Test, Determination of Total Phenol, Total Flavonoids and Antioxidant Activity of Ethanol Extract of Moringa Leaves (Moringa oleifera Lam)
Synthesis and Characterization of Triamine modified coated Iron Sand Hybrid Nanomaterials originating from Kendal Coast
Phenolic content and antioxidant activity of Moringa oleifera leaf infusions and tea
Last update: 2024-11-22 08:32:28
As an article writer, the author has the right to use their articles for various purposes, including use by institutions that employ authors or institutions that provide funding for research. Author rights are granted without special permission.
Author who publishes a paper at JKSA has the broad right to use their work for teaching and scientific purposes without the need to ask permission, including: used for (i) teaching in the author's class or institution, (ii) presentation at meetings or conferences and distributing copies to participants ; (iii) training conducted by the author or author's institution; (iv) distribution to colleagues for research use; (v) use in the compilation of subsequent authors' works; (vi) inclusion in a thesis or dissertation; (vi) reuse of part of the article in another work (with citation); (vii) preparation of derivative works (with citation); (viii) voluntary posting on open websites operated by authors or author institutions for scientific purposes (follow the CC BY-SA License).
Authors and readers can copy and redistribute material in any media or format, and mix, modify, and build material for any purpose but they must provide appropriate credit (provide article citation or content), providing links to the license, and indicate if there are changes.
The authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Jurnal Kimia Sains dan Aplikasi (JKSA). Copyright encompasses rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations.
Reproduce any part of this journal, its storage in the database or its transmission by all forms or media is permitted does not need for written permission from JKSA. However, it should be cited as an honor in academic manners
JKSA and the Chemistry Department of Diponegoro University and the Editor make every effort to ensure that there are no data, opinions, or false or misleading statements published in JKSA. However, the content of the article is the sole and exclusive responsibility of each author.
The Copyright Transfer Form can be downloaded here: [Copyright Transfer Form - Indonesian] [Copyright Transfer Form - English]. The copyright form should be signed originally and send to the Editor in the form of printed letters, scanned documents sent via email or fax.
Adi Darmawan, Ph.D (Editor in Chief)
Editor in chief of Jurnal Kimia Sains dan Aplikasi (JKSA)
Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University
Visitor: View My Stats
Jurnal Kimia Sains dan Aplikasi is indexed in:
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
