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Drug Dose Calculator Application to Prevent Medication Errors

Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sriwijaya/ Mohammad Hoesin Hospital Palembang, Indonesia

Published: 31 Jul 2022.
Open Access Copyright 2021 JAI (Jurnal Anestesiologi Indonesia)

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Abstract

As a part of the essentials in achieving patient safety, medication errors are one of the most financially detrimental problems in the treatment process faced by health institutions. This article firstly debriefs the definition of medication error and its general classification based on the treatment process. Wrong dose calculation has become one of the most frequent medication errors, especially among anesthesiology-care providers. This article then concisely defines the side effects of commonly-used anesthesia drugs in critical and perioperative care. This article examines medication errors prevalence among anesthesiologists and investigates the line between several risk factors and wrong dosage calculation. Finally, this article concludes with the elucidation of current trends of drug dosage calculators and several studies that aim to validate and prove the efficacy of those applications.

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MEDICATION ERRORS AMONG THE ANESTHETIC HEALTH CARE PROVIDERS AND THE ROLE OF DRUG DOSAGE CALCULATOR APPLICATIONS IN THEIR PREVENTION
Subject anesthetics, calculator application, drug dosage, medication error, patient safety
Type Other
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Type Other
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Keywords: anesthetics; calculator application; drug dosage; medication error; patient safety

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  1. Choi I, Lee SM, Flynn L, et al. Incidence and treatment costs attributable to medication errors in hospitalized patients. Research in Social and Administrative Pharmacy. 2016;12(3):428-437. doi: 10.1016/j.sapharm.2015.08.006
  2. Laatikainen O, Sneck S, Turpeinen M. The risks and outcomes resulting from medication errors reported in the Finnish tertiary care units: A cross-sectional retrospective register study. Frontiers in Pharmacology. 2020;10(January):1-11. doi: 10.3389/fphar.2019.01571
  3. Zhou S, Skaar DJ, Jacobson PA, Huang RS. Pharmacogenomics of Medications Commonly Used in the Intensive Care Unit. Frontiers in Pharmacology. 2018;9. doi: 10.3389/fphar.2018.01436
  4. Golembiewski J, Wheeler PJ. High-Alert Medications in the Perioperative Setting. Journal of Perianesthesia Nursing. 2007;22(6):435-437. doi: 10.1016/j.jopan.2007.09.002
  5. Cooper L, Nossaman B. Medication errors in anesthesia: A review. International Anesthesiology Clinics. 2013;51(1):1-12. doi: 10.1097/AIA.0b013e31827d6486
  6. Yamamoto M, Ishikawa S, Makita K. Medication errors in anesthesia: An 8-year retrospective analysis at an urban university hospital. Journal of Anesthesia. 2008;22(3):248-252. doi: 10.1007/s00540-008-0624-4
  7. Ulfah SS, Mita SR. Medication Errors Pada Tahap Prescribing, Transcribing, Dispensing Dan Administering. Farmaka. 2017;15(2):233-240
  8. Wuenstel A, Cheng P, Clebone A. New Applications for Your Mobile Device. Anesthesia & Analgesia. 2017;124(1):364. doi: 10.1213/ane.0000000000001694
  9. Siebert JN, Bloudeau L, Ehrler F, et al. A mobile device app to reduce prehospital medication errors and time to drug preparation and delivery by emergency medical services during simulated pediatric cardiopulmonary resuscitation: Study protocol of a multicenter, prospective, randomized controll. Trials. 2019;20(1):1-12. doi: 10.1186/s13063-019-3726-4
  10. James E. Integrating E-Calcutron into the Anesthesia Clinical Settings to Reduce Potential Medical Calculation Errors Among Student Registered Nurse Anesthetists. Published online 2020
  11. Green MS, Mathew JJ, Gundigi Venkatesh A, Green P, Tariq R. Utilization of Smartphone Applications by Anesthesia Providers. Anesthesiology Research and Practice. 2018;2018:5-9. doi: 10.1155/2018/8694357
  12. Pierce JMT, Taylor R. Validation of the mathematics in the anaesthetic impact calculator, a smartphone app for the calculation the CO2e of inhalational anaesthesia. Anaesthesia. 2020;75(1):136-138. doi: 10.1111/anae.14896
  13. Aronson JK. Medication errors: Definitions and classification. British Journal of Clinical Pharmacology. 2009;67(6):599-604. doi: 10.1111/j.1365-2125.2009.03415.x
  14. MacFie CC, Baudouin S V., Messer PB. An integrative review of drug errors in critical care. Journal of the Intensive Care Society. 2016;17(1):63-72. doi: 10.1177/1751143715605119
  15. Mackay E, Jennings J, Webber S. Medicines safety in anaesthetic practice. BJA Education. 2019;19(5):151-157. doi: 10.1016/j.bjae.2019.01.001
  16. Aronson JK. Medication errors: Definitions and classification. British Journal of Clinical Pharmacology. 2009;67(6):599-604. doi: 10.1111/j.1365-2125.2009.03415.x
  17. MacFie CC, Baudouin S V., Messer PB. An integrative review of drug errors in critical care. J Intensive Care Soc. 2016;17(1):63-72. doi: 10.1177/1751143715605119
  18. Mackay E, Jennings J, Webber S. Medicines safety in anaesthetic practice. BJA Education. 2019;19(5):151-157. doi: 10.1016/j.bjae.2019.01.001
  19. Beng yi S, Chan Pei Shan J, Lay Hong G. Medication reconciliation service in Tan Tock Seng Hospital. International Journal of Health Care Quality Assurance. 2013;26(1):31-36. doi: 10.1108/09526861311288622
  20. Ava Mansouria, Alireza Ahmadvandb, Molouk Hadjibabaiec, et al. A Review of Medication Errors in Iran: Sources, Underreporting Reasons and Preventive Measures. Iranian Journal of Pharmaceutical Research. 2014;13(1):3-17
  21. Anzan M, Alwhaibi M, Almetwazi M, Alhawassi TM. Prescribing errors and associated factors in discharge prescriptions in the emergency department: A prospective cross-sectional study. PLoS ONE. 2021;16(1 January). doi: 10.1371/journal.pone.0245321
  22. Sari DD, Oktarlina RZ. Peresepan Obat Rasional dalam Mencegah Kejadian Medication Error. Jurnal Kedokteran Universitas Lampung. 2017;7(5):100-105
  23. Kabra A, Kabra R. Study of medication errors and compliances for inclusion of new drugs in hospital formulary International Journal of Fundamental & Applied Sciences Study of medication errors and compliances for inclusion of new drugs in hospital formulary. 2020;(May):13-16
  24. Khairurrijal MAW, Putriana NA. Review : Medication Erorr Pada Tahap Prescribing, Transcribing, Dispensing, dan Administration. Farmasetika.com (Online). 2018;2(4):8. doi: 10.24198/farmasetika.v2i4.15020
  25. Gloria L, Yuwono, Ngudiantoro. Analisis Faktor Yang Mempengaruhi Medication Error Pada Pasien Kemoterapi Di RSUP DR . Mohammad Hoesin Palembang. Majalah Kedokteran Sriwijaya. 2017;4(49):178-184
  26. Alomar M, Ahmad S, Moustafa Y, Alharbi L. Reducing missed medication doses in intensive care units: A pharmacist-led intervention. Journal of Research in Pharmacy Practice. 2020;9(1):36. doi: 10.4103/jrpp.jrpp_19_95
  27. Tsegaye D, Alem G, Tessema Z, Alebachew W. Medication administration errors and associated factors among nurses. International Journal of General Medicine. 2020;13:1621-1632. doi: 10.2147/IJGM.S289452
  28. Park KK, Sharon VR. A Review of Local Anesthetics : Minimizing Risk and Side Effects in Cutaneous Surgery. Published online 2017:173-187. doi: 10.1097/DSS.0000000000000887
  29. El-Boghdadly K, Pawa A, Chin KJ. Local anesthetic systemic toxicity: Current perspectives. Local and Regional Anesthesia. 2018;11:35-44. doi: 10.2147/LRA.S154512
  30. Di Gregorio G, Neal JM, Rosenquist RW, Weinberg GL. Clinical presentation of local anesthetic systemic toxicity: A review of published cases, 1979 to 2009. Regional Anesthesia and Pain Medicine. 2010;35(2):181-187. doi: 10.1097/AAP.0b013e3181d2310b
  31. To D, Gannes G De. Lidocaine Contact Allergy Is Becoming More Prevalent. Published online 2014:1367-1372. doi: 10.1097/DSS.0000000000000190
  32. Erwin PJ, Anderson JR, Miner JR, Hess EP. Incidence of Adverse Events in Adults Undergoing Procedural Sedation in the Emergency Department: A Systematic Review and Meta-analysis. Academic Emergency Medicine. 2016;23(0):119-134. doi: 10.1111/acem.12875
  33. Yaacoub S. General Anesthesia : A Literature Review - Induction , Mechanism , Agents , and Effects. 2015
  34. Löser B, Petzoldt M, Löser A, Douglas R. Intravenous Regional Anesthesia: A historical overview and clinical review. Journal of Anesthesia History. 2018;7(10):1-32. doi: 10.1016/j.janh.2018.10.007
  35. Moore RA, Mcquay HJ. Prevalence of opioid adverse events in chronic non-malignant pain : Systematic review of randomised trials of oral opioids. Arthritis Research & Therapy. 2005;7(5):1046-1051. doi: 10.1186/ar1782
  36. Verberkt CA, Everdingen MHJVDB van, Schols JMGA, et al. Respiratory adverse effects of opioids for breathlessness : a systematic review and meta-analysis. Eur Respir J. 2017;50(1153):1-15. doi: 10.1183/13993003.01153-2017
  37. Frauenknecht J, Kirkham KR, Albrecht E. Analgesic impact of intra-operative opioids vs . opioid-free anaesthesia : A systematic review and meta-analysis. Published online 2019. doi: 10.1111/anae.14582
  38. Demiri M, Antunes T, Fletcher D, Martinez V. Perioperative adverse events attributed to a 2-adrenoceptor agonists in patients not at risk of cardiovascular events : systematic review and meta-analysis. British Journal of Anaesthesia. 2019;123(6):795-807. doi: 10.1016/j.bja.2019.07.029
  39. Bouri S, Shun-shin MJ, Cole GD, Mayet J, Francis DP. Meta-analysis of secure randomised controlled trials of β -blockade to prevent perioperative death in non-cardiac surgery. Published online 2014:456-464. doi: 10.1136/heartjnl-2013-304262
  40. Wijeysundera DN, Committee ER, Duncan D, et al. Perioperative Beta Blockade in Noncardiac Surgery : A Systematic Review for the 2014 ACC / AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery. 2014;64(22). doi: 10.1016/j.jacc.2014.07.939
  41. Farzam; K, Kidron; A, Lakhkar. AD. Adrenergic Drugs. StatPearls. 2021;1(1)
  42. Clar D, Liu M. Non-depolarizing Neuromuscular Blockers. In: StatPearls. StatPearls Publishing; 2021:1-6
  43. Vilardi V, Sanfilippo M, Crarlone A. Muscle Relaxants : Side Effects and Complications. Published online 2001
  44. Nanji KC, Patel A, Shaikh S, Seger DL, Bates DW. Evaluation of Perioperative Medication Errors and Adverse Drug Events. Anesthesiology. 2016;124(1):25-34. doi: 10.1097/ALN.0000000000000904
  45. Erdmann TR, Garcia JHS, Loureiro ML, Monteiro MP, Brunharo GM. Profile of drug administration errors in anesthesia among anesthesiologists from Santa Catarina. Brazilian Journal of Anesthesiology (English Edition). 2016;66(1):105-110. doi: 10.1016/j.bjane.2014.06.011
  46. Anzan M, Alwhaibi M, Almetwazi M, Alhawassi TM. Prescribing errors and associated factors in discharge prescriptions in the emergency department: A prospective cross-sectional study. PLoS ONE. 2021;16(1 January). doi: 10.1371/journal.pone.0245321
  47. Vaziri S, Fakouri F, Mirzaei M, Afsharian M, Azizi M, Arab-Zozani M. Prevalence of medical errors in Iran: A systematic review and meta-Analysis. BMC Health Services Research. 2019;19(1):1-11. doi: 10.1186/s12913-019-4464-8
  48. Thomas B, Paudyal V, MacLure K, et al. Medication errors in hospitals in the Middle East: a systematic review of prevalence, nature, severity and contributory factors. European Journal of Clinical Pharmacology. 2019;75(9):1269-1282. doi: 10.1007/s00228-019-02689-y
  49. Swinton P, Corfield AR, Moultrie C, et al. Impact of drug and equipment preparation on pre-hospital emergency Anaesthesia (PHEA) procedural time, error rate and cognitive load. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2018;26(1):1-10. doi: 10.1186/s13049-018-0549-3
  50. Gloria L, Yuwono, Ngudiantoro. Analisis Faktor Yang Mempengaruhi Medication Error Pada Pasien Kemoterapi Di RSUP DR . Mohammad Hoesin Palembang. Majalah Kedokteran Sriwijaya. 2017;4(49):178-184
  51. Hartati, Lolok NH, Fudholi A. Analisis Kejadian Medication Error Pada Pasien ICU. Journal of Management and Pharmacy Practice. 2014;4(2):125-132. doi: 10.22146/jmpf.277
  52. Ulfah SS, Mita SR. Medication Errors Pada Tahap Prescribing, Transcribing, Dispensing Dan Administering. Farmaka. 2017;15(2):233-240
  53. Oktarlina RZ, Wafiyatunisa Z. Kejadian Medication Error pada Fase Prescribing di Poliklinik Pasein Rawat Jalan Rumah Sakit Daerah Mayjend HM Ryacudu Kota Bumi. Fakultas Kedokteran Universitas Lampung. 2017;1(3):540-545
  54. Merry AF, Anderson BJ. Medication errors - New approaches to prevention. Paediatric Anaesthesia. 2011;21(7):743-753. doi: 10.1111/j.1460-9592.2011.03589.x
  55. Cohen MR, Orser B. Perioperative Medication Errors; Building Safer Systems. 2016;(1):1-3
  56. Dhawan I, Tewari A, Sehgal S, Sinha AC. Medication errors in anesthesia: unacceptable or unavoidable? Brazilian Journal of Anesthesiology (English Edition). 2017;67(2):184-192. doi: 10.1016/j.bjane.2015.09.006
  57. Gariel C, Cogniat B, Desgranges FP, Chassard D, Bouvet L. Incidence, characteristics, and predictive factors for medication errors in paediatric anaesthesia: a prospective incident monitoring study. British Journal of Anaesthesia. 2018;120(3):563-570. doi: 10.1016/j.bja.2017.12.014
  58. Woo Y, Kim HE, Chung S, Park BJ. Pediatric medication error reports in Korea adverse event reporting system database, 1989-2012: Comparing with adult reports. Journal of Korean Medical Science. 2015;30(4):371-377. doi: 10.3346/jkms.2015.30.4.371
  59. Boytim J, Ulrich B. Factors contributing to perioperative medication errors: A systematic literature review. AORN Journal. 2018;107(1):91-107. doi: 10.1002/aorn.12005
  60. Alomar M, Ahmad S, Moustafa Y, Alharbi L. Reducing missed medication doses in intensive care units: A pharmacist-led intervention. Journal of Research in Pharmacy Practice. 2020;9(1):36. doi: 10.4103/jrpp.jrpp_19_95
  61. Ariyaratnam R, Palmqvist CL, Hider P, et al. Toward a standard approach to measurement and reporting of perioperative mortality rate as a global indicator for surgery. Surgery (United States). 2015;158(1):17-26. doi: 10.1016/j.surg.2015.03.024
  62. Siebert JN, Bloudeau L, Ehrler F, et al. A mobile device app to reduce prehospital medication errors and time to drug preparation and delivery by emergency medical services during simulated pediatric cardiopulmonary resuscitation: Study protocol of a multicenter, prospective, randomized controll. Trials. 2019;20(1):1-12. doi: 10.1186/s13063-019-3726-4
  63. Carvalho H, Verdonck M, Forget P, Poelaert J. Acceptance of mHealth among health professionals: A case study on anesthesia practitioners. BMC Anesthesiology. 2020;20(1):1-10. doi: 10.1186/s12871-020-00958-3
  64. Green MS, Mathew JJ, Gundigi Venkatesh A, Green P, Tariq R. Utilization of Smartphone Applications by Anesthesia Providers. Anesthesiology Research and Practice. 2018;2018:5-9. doi: 10.1155/2018/8694357
  65. Wong I. Ways to reduce drug dose calculation errors in children. 2010;15(January):2009-2011
  66. Kirk RC, Goh DL meng, Packia J, Kam HM, Ong BKC. Computer Calculated Dose in Paediatric Prescribing. Drug Safety. 2005;28(9):817-824
  67. Wuenstel A, Cheng P, Clebone A. New Applications for Your Mobile Device. Anesthesia & Analgesia. 2017;124(1):364. doi: 10.1213/ane.0000000000001694
  68. James E. Integrating E-Calcutron into the Anesthesia Clinical Settings to Reduce Potential Medical Calculation Errors Among Student Registered Nurse Anesthetists. Published online 2020
  69. Zanden TM Van Der, Goedknegt L, Hoog M De, Mooij MG, Wildt SN De. Development and implementation of a paediatric dosing calculator integrated in the Dutch Paediatric Formulary. Drugs & Therapy Perspectives. 2020;36(6):253-262. doi: 10.1007/s40267-020-00724-y
  70. Murray B, Streitz MJ, Hilliard M, Maddry JK. Evaluation of an Electronic Dosing Calculator to Reduce Pediatric Medication Errors. Clinical Pediatrics. 2019;58(4):413-416. doi: 10.1177/0009922818821871
  71. Pierce JMT, Taylor R. Validation of the mathematics in the anaesthetic impact calculator, a smartphone app for the calculation the CO2e of inhalational anaesthesia. Anaesthesia. 2020;75(1):136-138. doi: 10.1111/anae.14896
  72. Baumann D, Dibbern N, Sehner S, Zöllner C, Reip W, Kubitz JC. Validation of a mobile app for reducing errors of administration of medications in an emergency. Journal of Clinical Monitoring and Computing. 2019;33(3):531-539. doi: 10.1007/s10877-018-0187-3
  73. Jara CP, Carraro RS, Zanesco A, et al. A Smartphone App for Individual Xylazine / Ketamine Calculation Decreased Anesthesia-Related Mortality in Mice. 2021;8(July):1-7. doi: 10.3389/fvets.2021.651202

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